Comfort Inn & Suites Sikeston I-55
Hotel in Sikeston with a fitness center and a 24-hour front desk
Choose dates to view prices
Photo gallery for Comfort Inn & Suites Sikeston I-55





Reviews
8.4 out of 10
Very good
Popular amenities
Explore the area

109 Matthews Ln, Sikeston, MO, 63801
- Place, City of Miner Convention Center5 min walk
- Place, Central Park5 min drive
- Place, Sikeston Depot Museum6 min drive
- Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)31 min drive
Room options
View all photos for Standard Room, 2 Queen Beds, Non Smoking

Standard Room, 2 Queen Beds, Non Smoking
8.0 out of 10
Very good
(11 reviews)
View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking
View all photos for Room, 1 King Bed, Accessible, Non Smoking

Room, 1 King Bed, Accessible, Non Smoking
9.0 out of 10
Wonderful
(2 reviews)
View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

Room, 2 Queen Beds, Accessible, Non Smoking
10.0 out of 10
Exceptional
(4 reviews)
View all photos for Standard Room, 1 King Bed, Non Smoking

Standard Room, 1 King Bed, Non Smoking
8.0 out of 10
Very good
(14 reviews)
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- Pet friendly
- Parking included
8.8 out of 10, Excellent, 407 reviews
$106 nightly
The price is $120
Oct 26 - Oct 27
Total with taxes and fees
About the neighborhood
About this property
Comfort Inn & Suites Sikeston I-55
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Best Western Plus Sikeston
Best Western Plus Sikeston
- Pool
- Breakfast included
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8.4 out of 10, Very Good, 1,008 reviews
$84 nightly
The price is $96
Oct 19 - Oct 20
Total with taxes and fees
Property amenities
Room amenities
Policies
Important information
Frequently asked questions
Comfort Inn & Suites Sikeston I-55 Reviews
Reviews
8.4
Very Good
8.4/10
Cleanliness
8.8/10
Staff & service
8.2/10
Amenities
8.2/10
Property conditions & facilities
8.2/10
Eco-friendliness
Reviews
Jul 10, 2025
Stayed 1 night in Jul 2025
8/10 Good
Juanita
Traveled with family
Jul 5, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Juanita
Stayed 3 nights in Jun 2025
6/10 Okay
Juanita
Traveled with family
Jun 30, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Juanita
Stayed 3 nights in Jun 2025
4/10 Poor
Latrisha, Kalamazoo
Traveled with partner
Jun 29, 2025
Disliked: Cleanliness, amenities, property conditions & facilities




Latrisha
Stayed 2 nights in Jun 2025
6/10 Okay
Wendy
Traveled with family
Jun 26, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Wendy
Stayed 1 night in Jun 2025
10/10 Excellent
Corinthian
Jun 24, 2025
Liked: Cleanliness, amenities, property conditions & facilities
Corinthian
Stayed 3 nights in May 2025
8/10 Good
Sidney
Jun 24, 2025
Sidney
Stayed 1 night in Jun 2025
8/10 Good
George
Traveled with family
Jun 7, 2025
Liked: Cleanliness, amenities, property conditions & facilities
George
Stayed 1 night in Jun 2025
10/10 Excellent
Francis
Jun 3, 2025
Francis
Stayed 1 night in Jun 2025
4/10 Poor
Elmarie
Jun 2, 2025
Liked: Property conditions & facilities
Elmarie
Stayed 1 night in May 2025
6/10 Okay
Latrisha, Kalamazoo
Traveled with partner
May 30, 2025
Disliked: Cleanliness
Latrisha
Stayed 2 nights in Apr 2025
8/10 Good
David
May 26, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
David
Stayed 1 night in May 2025
8/10 Good
Patricia, Richmond
May 25, 2025
Patricia
Stayed 1 night in May 2025
10/10 Excellent
Peggy
May 14, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Peggy
Stayed 2 nights in May 2025
10/10 Excellent
Timothy, Hartford
Traveled with family
May 11, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Timothy
Stayed 1 night in May 2025
8/10 Good
John
May 9, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Good stay
John
Stayed 1 night in May 2025
8/10 Good
Luther
Traveled with family
May 7, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Luther
Stayed 2 nights in Feb 2025
10/10 Excellent
Sharon
Traveled with partner
Apr 29, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Sharon
Stayed 1 night in Apr 2025
10/10 Excellent
Allan
Apr 22, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Allan
Stayed 1 night in Apr 2025
10/10 Excellent
Meaghan
Apr 11, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Meaghan
Stayed 1 night in Apr 2025
8/10 Good
Frank
Apr 7, 2025
Frank
Stayed 2 nights in Apr 2025
10/10 Excellent
Marsha
Traveled with partner
Apr 5, 2025
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Marsha
Stayed 1 night in Apr 2025
8/10 Good
Sheila a
Business traveler
Mar 28, 2025
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Quiet
Sheila a
Stayed 2 nights in Mar 2025
10/10 Excellent
Becky
Mar 24, 2025
Liked: Cleanliness, staff & service, property conditions & facilities
Becky
Stayed 1 night in Mar 2025
6/10 Okay
Mary Jane
Traveled with partner
Mar 23, 2025
Disliked: Property conditions & facilities
Mary Jane
Stayed 1 night in Mar 2025
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