Comfort Inn & Suites Sikeston I-55

2.5 star property
Hotel in Sikeston with a fitness center and a 24-hour front desk

Choose dates to view prices

Photo gallery for Comfort Inn & Suites Sikeston I-55

Exterior
1 bedroom, desk, free WiFi, bed sheets
Lobby
Indoor pool
Breakfast area

Reviews

8.4 out of 10
Very good

Popular amenities

  • Gym
  • Laundry
  • Pet friendly
  • Parking included
  • Free WiFi

Explore the area

View in a map
109 Matthews Ln, Sikeston, MO, 63801
  • Place, City of Miner Convention Center
    ‪5 min walk‬
  • Place, Central Park
    ‪5 min drive‬
  • Place, Sikeston Depot Museum
    ‪6 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪31 min drive‬

Room options

Standard Room, 2 Queen Beds, Non Smoking

8.0 out of 10
Very good
(11 reviews)
  • Sleeps 4
  • 2 Queen Beds

Suite, 1 King Bed with Sofa bed, Non Smoking

  • 1 bedroom
  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

Room, 1 King Bed, Accessible, Non Smoking

9.0 out of 10
Wonderful
(2 reviews)
  • Sleeps 2
  • 1 King Bed

Room, 2 Queen Beds, Accessible, Non Smoking

10.0 out of 10
Exceptional
(4 reviews)
  • Sleeps 4
  • 2 Queen Beds

Standard Room, 1 King Bed, Non Smoking

8.0 out of 10
Very good
(14 reviews)
  • Sleeps 2
  • 1 King Bed

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About the neighborhood

Sikeston

Located within a leisurely stroll of City of Miner Convention Center, Comfort Inn & Suites Sikeston I-55 is within a 10-minute drive of Sikeston Depot Museum. This 64-room hotel welcomes guests with conveniences like an indoor pool, free in-room WiFi, and free self parking.

What's nearby

  • City of Miner Convention Center - 5 min walk - 0.3 miles
  • Central Park - 5 min drive - 3.5 miles
  • Sikeston Depot Museum - 6 min drive - 3.5 miles
  • Southeast Missouri State University - 41 min drive - 37.6 miles
  • Isle Casino Cape Girardeau - 42 min drive - 38.0 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 29 min drive

Restaurants

  • ‪Lambert's Cafe - ‬17 min walk
  • ‪Buffalo Wild Wings - ‬5 min drive
  • ‪Pizza Inn - ‬2 min drive
  • ‪McDonald's - ‬2 min walk
  • ‪Burger King - ‬4 min drive

About this property

Comfort Inn & Suites Sikeston I-55

Hotel in Sikeston with a fitness center and a 24-hour front desk
At Comfort Inn & Suites Sikeston I-55, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a business center and laundry facilities.
Guests can expect to find free WiFi. Other amenities include coffee makers, phones, and desks.
Recreational amenities at the hotel include an indoor pool and a fitness center.

Similar properties

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Things to do

  • Gym
  • Indoor pool

Family friendly

  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Safe at front desk

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible registration desk

More

  • 3 floors
  • Smoking not allowed

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Bathtub or shower
  • Private bathroom
  • Towels provided

Entertainment

  • Cable/satellite channels

Food and drink

  • Coffee/tea maker

More

  • Air conditioning
  • Desk
  • Phone

Policies

Check-in

Check-in start time: 2:00 PM; Check-in end time: anytime
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 20 per pet, per night
  • Dogs and cats only
  • 2 total (20 lbs is the maximum weight per pet)
  • Certain rooms only
  • Guests can request a pet-friendly room by contacting the property at the number on the booking confirmation
  • Service animals exempt from fees

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Pet fee: USD 20 per pet, per night
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
  • Check-in: 2:00 PM
  • Check-out: 11:00 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice).

Additional information about polices, regulations, and more:

  • No cribs or infant beds are available.
  • No rollaway or extra beds are available.

Property is also known as

Comfort Inn Sikeston Hotel
Comfort Inn Sikeston

Frequently asked questions

Is free cancellation available at Comfort Inn & Suites Sikeston I-55?

Comfort Inn & Suites Sikeston I-55 provides free cancellation on some room rates. For additional details, look at the cancellation policy on our site.

How much does it cost to stay at Comfort Inn & Suites Sikeston I-55?

As of Oct 14, 2025, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Sikeston I-55 on Oct 24, 2025 start from $92.65, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What's there to do close to Comfort Inn & Suites Sikeston I-55?

This hotel is located in Sikeston, close to Central Park and Sikeston Depot Museum.

Is there parking available at Comfort Inn & Suites Sikeston I-55?

Yes, self parking is offered for free at the hotel. Accessible parking is also available for guests.

Does Comfort Inn & Suites Sikeston I-55 have a casino?

No, Comfort Inn & Suites Sikeston I-55 doesn't have a casino.

Is there an indoor pool at Comfort Inn & Suites Sikeston I-55?

Yes, this hotel has an indoor pool.

Is Comfort Inn & Suites Sikeston I-55 a good place to stay for couples?

Amenities at this hotel that appeal to couples include an indoor pool and a 24-hour front desk.

Does Comfort Inn & Suites Sikeston I-55 have a hot tub?

No, this hotel doesn't have a spa tub.

Does Comfort Inn & Suites Sikeston I-55 have a restaurant that serves breakfast?

No, Comfort Inn & Suites Sikeston I-55 doesn't have a restaurant that serves breakfast.

Does Comfort Inn & Suites Sikeston I-55 allow pets to stay for free?

Although they can't stay for free, cats and dogs are welcome at Comfort Inn & Suites Sikeston I-55 for a fee of USD 20 per pet, per night.

Are there connecting rooms at Comfort Inn & Suites Sikeston I-55?

No, this hotel doesn't feature connecting guestrooms.

How far is the airport from Comfort Inn & Suites Sikeston I-55?

The closest major airport to Comfort Inn & Suites Sikeston I-55 is Cairo, IL (CIR-Cairo Regional), which is 28.1 mi away (29 minutes by car). Another top airport is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is located 26.7 mi away (29-minute drive).

Are there rooms with balconies at Comfort Inn & Suites Sikeston I-55?

No, at Comfort Inn & Suites Sikeston I-55, there aren't any guestrooms that list a balcony.

Comfort Inn & Suites Sikeston I-55 Reviews

Reviews

8.4

Very Good

Rating 10 - Excellent. 126 out of 272 reviews
Rating 8 - Good. 91 out of 272 reviews
Rating 6 - Okay. 28 out of 272 reviews
Rating 4 - Poor. 18 out of 272 reviews
Rating 2 - Terrible. 9 out of 272 reviews

8.4/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.2/10

Property conditions & facilities

8.2/10

Eco-friendliness

Reviews

10/10 Excellent

Antonio

Stayed 1 night in Jul 2025

8/10 Good

Juanita

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Jun 2025

6/10 Okay

Juanita

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
The check in guy threw my id at me and was rude
Stayed 3 nights in Jun 2025

4/10 Poor

Latrisha, Kalamazoo

Traveled with partner
Disliked: Cleanliness, amenities, property conditions & facilities
Pet hair all iver the chair in the room. Specs of poop on toilet seat. Ironing board filthy. Linens torn. Lumpy pillows. Distinct smell of room a mnd hallway stairs. Side doors not secure. Holes in closet door. Freezer portion of fridge was dirty. Watery powdered eggs and hard biscuits. Had to purchase clorox cleaning wipes to wipe down everything, went through entire bottle. Used entire bottle of febreeze. First stay was okay. Last couple has been terrible, but price of rooms increased. Lady at front desk was nice was about all i liked about sleeping there. Last stay at Comfort Inn as it's not worth the price.
Stayed 2 nights in Jun 2025

6/10 Okay

Wendy

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Everything was good. The beds were too hard and pillows were too soft.
Stayed 1 night in Jun 2025

10/10 Excellent

Corinthian

Liked: Cleanliness, amenities, property conditions & facilities
It was cool
Stayed 3 nights in May 2025

8/10 Good

Sidney

Stayed 1 night in Jun 2025

8/10 Good

George

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
Clean
Stayed 1 night in Jun 2025

10/10 Excellent

Francis

Stayed 1 night in Jun 2025

4/10 Poor

Elmarie

Liked: Property conditions & facilities
Had a barking dog next door. Had to work on heater the knob was messed up. Had to call for someone to come fix tv and it still never worked the best
Stayed 1 night in May 2025

6/10 Okay

Latrisha, Kalamazoo

Traveled with partner
Disliked: Cleanliness
Toilet did not flush. Heard water dripping from shower all night. Had to request a different room. Beds were comfortable. Furniture can use cleaning/dusting. Freezer had something wasted in it. Staff was friendly at the front desk.
Stayed 2 nights in Apr 2025

8/10 Good

David

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

8/10 Good

Patricia, Richmond

Stayed 1 night in May 2025

10/10 Excellent

Peggy

Liked: Cleanliness, staff & service, property conditions & facilities
The facility was very nice.
Stayed 2 nights in May 2025

10/10 Excellent

Timothy, Hartford

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean & friendly service. Easy access from the highway. Bed is comfortable. Breakfast area looks very nice. A good selection of food choices. Would recommend this property. The ice machine wasn’t working on our floor, but could get ice near the lobby, so not a huge issue.
Stayed 1 night in May 2025

8/10 Good

John

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good stay

It was decent…slept well The room was clean
Stayed 1 night in May 2025

8/10 Good

Luther

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Feb 2025

10/10 Excellent

Sharon

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice
Stayed 1 night in Apr 2025

10/10 Excellent

Allan

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Apr 2025

10/10 Excellent

Meaghan

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Apr 2025

8/10 Good

Frank

Stayed 2 nights in Apr 2025

10/10 Excellent

Marsha

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was okay, quiet and helpful.
Stayed 1 night in Apr 2025

8/10 Good

Sheila a

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Quiet

Clean enough though older. Main thing for me was peace and quiet so I could sleep during the day ( working nights while in town). That was great!
Stayed 2 nights in Mar 2025

10/10 Excellent

Becky

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Mar 2025

6/10 Okay

Mary Jane

Traveled with partner
Disliked: Property conditions & facilities
In need of maintenance
Stayed 1 night in Mar 2025