Santa Cruz Vacation Homes

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Featured Vacation Homes in Santa Cruz

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Santa Cruz

    Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

    Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

    Ave. San Martin, #455 Santa Cruz
    $127 nightly
    The price is $127 total per night from Aug 4 to Aug 5
    $127 total
    Aug 4 - Aug 5
    9/10 Wonderful! (392 reviews)
    Ibis Santa Cruz DE LA Sierra

    Ibis Santa Cruz DE LA Sierra

    AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
    $53 nightly
    The price is $53 total per night from Aug 5 to Aug 6
    $53 total
    Aug 5 - Aug 6
    9.4/10 Exceptional! (126 reviews)
    Camino Real Hotel

    Camino Real Hotel

    Av. San Martín y 4to. Anillo Santa Cruz
    $145 nightly
    The price is $145 total per night from Aug 4 to Aug 5
    $145 total
    Aug 4 - Aug 5
    9/10 Wonderful! (433 reviews)

Santa Cruz Vacation Homes

Book vacation homes in Santa Cruz
Next time you take a group getaway top Santa Cruz, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Santa Cruz vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Santa Cruz vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Santa Cruz; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Santa Cruz rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Santa Cruz is sure to be a winner.

Santa Cruz Vacation Homes essential information

Accommodation
10 Vacation Homes
Lowest Price
$52
Highest Price
$145
Popular accommodation
Cozy 1-bedroom house in beautiful Santa Cruz de la Sierra with WiFi, AC, Casa Vida, Casa Natura - Exquisite 3 Bedroom Ocean View Home, Cozy and independent.
Downtown house JH., Mi casa su casa, moderna y chic., Exclusive Condominium Home - Resort Style Living with Pool and Parks ‍♂️, Casa por Temporadas, Vacation Rental - Santa Cruz, Bolivia, Charming 2-bedroom house in lovely Santa Cruz with AC, WiFi