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617 Travelers rated Main Street Hyannis highly for Seafood and Shopping

Book a package and join the 188 others who’ve received 100% off their flights this year!
Book a package and join the 188 others who’ve received 100% off their flights this year!
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Book a package and join the 188 others who’ve received 100% off their flights this year!

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Top Rated Hotels for your Main Street Hyannis Vacation

Hyannis Inn
Hyannis Inn
2.0 out of 5.0 473 MAIN ST, Hyannis, MA
$3,010
4.0/5 (11 reviews)

Staff was amazing and super helpful with hotel information. Even upgraded my room cause I was in town for a road race.

Reviewed on Sep 29, 2019
Located in the heart of Hyannis, this motel is within a 15-minute walk of St. Francis Xavier Church and Hyannis Harbor. Cape Codder Water Park is 2.1 mi (3.4 ...

Things To Do during your Main Street Hyannis Vacation

See all 3 things to do in Main Street Hyannis

Tips for planning your Main Street Hyannis vacation

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Join Orbitz Rewards

Just kick back, take a load off and let Orbitz help you create a truly amazing Main Street Hyannis trip. If you're looking to package your hotel and flight options to save heaps, you're where you need to be!

A perfect way to save money is to bundle your bookings. You can save up to $420^ by selecting your choice of hotels, airfares, rental cars and experiences with us.

And more great news — if you're not quite sure where to stay or who to fly with, our database has no less than 500,000 hotels worldwide and 500 airlines. It's completely your choice!

It doesn't matter what type of experience you're searching for, there are limitless options to create the trip of your dreams.

Join Orbitz Rewards

How do you like the sound of instant rewards? Simply keep booking with us and you'll gain Orbucks! It's a simple system we've built to reward you, lightning fast!

One more thing, stay four nights for gold membership and 12 nights for platinum membership. So, what does that get you? Well, you'll have all sorts of special perks at all Orbitz Rewards VIP Hotels. And how do you redeem? It's a breeze — just use your Orbitz Rewards points on your following booking.

Main Street Hyannis Travel Guide

Where is Main Street Hyannis?

Part of the joy of traveling is the anticipation you feel before you arrive. Start getting excited about your Main Street Hyannis getaway by finding out a few things about it!

It's a neighborhood of Hyannis. You'll find it 0.08 miles southwest of the downtown area.

There are approximately 14,000 people that live in Hyannis.

Places to Visit in Main Street Hyannis

Take a stroll along the waterfront and enjoy the view at Hyannis Harbor. Want more nearby options? John F. Kennedy Hyannis Museum has a wide range of historical displays, enabling visitors to experience the stories and people that influenced this area. But wait, that's not all there is. See who's the best putter as you work your way around the challenging holes of Wild Animal Lagoon.

Car Rentals in Main Street Hyannis

Want to explore the region on your own terms? Be the creator of your own adventure by checking out car rentals in Main Street Hyannis with a little help from Orbitz.

Picking up the car keys from Barnstable Municipal Airport means you'll be off the plane and into the driver's seat in no time at all. Budget and Avis are both options worth looking at.

Renting a ride right from the heart of the city can be convenient if you're staying nearby. Head to Thrifty Car Rental, which you can find at 220 Ocean Street Dock. Hertz at 223 Stevens Street is another vendor to stop by.

Where to stay in Main Street Hyannis – Hotel Accommodation

Orbitz can help you choose the nicest place to crash in this great destination. Currently, we list 70 hotels in Main Street Hyannis.

We'll try to make booking your getaway as simple and easy as possible. Recommended accommodations include the Red Jacket Beach Resort and Green Harbor Resort.

Nearest Airports to Main Street Hyannis

Tuck away your tray table, put your seat in the upright position and get ready to land at Logan International Airport (BOS). The entry point to your next big adventure, the terminal is 60 miles northwest of Main Street Hyannis.

Popular Places to Visit Near Main Street Hyannis

Hyannis and Hyannis Port are well worth a visit while you are here. Hyannis is approximately 0.7 miles away, and Hyannis Port is 2 miles away.

No Cancellation Fees

Plans can change in a flash, which is why we won't ask for a fee if you need to alter or cancel your booking.^ However, it's a good idea to find out if your airline and hotel will do the same.

^Savings based on all package bookings with Flight + Hotel made on Orbitz.com from January 1, 2018 to December 31, 2018 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.

*Price based on the lowest price found within past 24 hours and based upon one night stay for two adults over the next thirty days. Prices and availability subject to change. Additional terms may apply.