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21c Museum Hotel Louisville

4.5 star property
Luxury hotel with a full-service spa and a 24-hour fitness center

Choose dates to view prices

Photo gallery for 21c Museum Hotel Louisville

Standing proudly in front of a classical building, a majestic statue takes center stage.
Experience a sophisticated atmosphere with exposed brick walls, polished concrete floors, and a striking staircase.
Relax in a stylish space with a unique ceiling design, comfortable seating area, and artwork-adorned walls.
Relax with friends at the bar, where framed artwork and a chandelier create a welcoming atmosphere.
Traditional stone well surrounded by a cobblestone pathway in a narrow alleyway.

Reviews

9.2 out of 10
Wonderful

Popular amenities

  • Spa
  • Room service
  • Pet friendly

Explore the area

Map
700 W Main Street, Louisville, KY, 40202
  • Louisville Slugger Museum
    ‪3 min walk‬
  • Kentucky International Convention Center
    ‪8 min walk‬
  • KFC Yum Center
    ‪8 min walk‬
  • Louisville, KY (SDF-Louisville Intl.)
    ‪9 min drive‬

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Room options

View all photos for Luxury Double Room, 2 Double Beds

Luxury Double Room, 2 Double Beds | 1 bedroom, premium bedding, down comforters, minibar

Luxury Double Room, 2 Double Beds

9.0 out of 10
Wonderful
(2 reviews)
  • 435 sq ft
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Double Room, 2 Double Beds

1 bedroom, premium bedding, down comforters, minibar

Deluxe Double Room, 2 Double Beds

9.6 out of 10
Exceptional
(28 reviews)
  • 335 sq ft
  • Sleeps 4
  • 2 Double Beds

View all photos for Luxury Room, 1 King Bed

Luxury Room, 1 King Bed | 1 bedroom, premium bedding, down comforters, minibar

Luxury Room, 1 King Bed

9.0 out of 10
Wonderful
(29 reviews)
  • 455 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed

1 bedroom, premium bedding, down comforters, minibar

Deluxe Room, 1 King Bed

9.6 out of 10
Exceptional
(61 reviews)
  • 350 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Suite, Corner

Suite, Corner | 1 bedroom, premium bedding, down comforters, minibar

Suite, Corner

  • 660 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Apartment, 1 Double Bed (Rooftop)

Apartment, 1 Double Bed (Rooftop) | 1 bedroom, premium bedding, down comforters, minibar

Apartment, 1 Double Bed (Rooftop)

  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Double Room, Accessible

1 bedroom, premium bedding, down comforters, minibar

Deluxe Double Room, Accessible

10.0 out of 10
Exceptional
(1 review)
  • 455 sq ft
  • Sleeps 4
  • 2 Double Beds

View all photos for Suite (Atrium)

Suite (Atrium) | 1 bedroom, premium bedding, down comforters, minibar

Suite (Atrium)

  • 580 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Room, Balcony

Room, Balcony | 1 bedroom, premium bedding, down comforters, minibar

Room, Balcony

  • 315 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Room (Asleep in the Cyclone)

Room (Asleep in the Cyclone) | 1 bedroom, premium bedding, down comforters, minibar

Room (Asleep in the Cyclone)

  • 500 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed, Accessible

1 bedroom, premium bedding, down comforters, minibar

Deluxe Room, 1 King Bed, Accessible

  • 435 sq ft
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed, Accessible

1 bedroom, premium bedding, down comforters, minibar

Deluxe Room, 1 King Bed, Accessible

  • 434 sq ft
  • Sleeps 3
  • 1 King Bed

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About the neighborhood

Louisville

Located in Downtown Louisville, 21c Museum Hotel Louisville is adjacent to Louisville Slugger Museum and within a 10-minute walk of other popular attractions like KFC Yum Center. This 91-room, 4.5-star hotel has a restaurant, a full-service spa, and a 24-hour gym.

What's nearby

  • Muhammad Ali Center - 3 min walk - 0.2 miles
  • Louisville Slugger Museum - 3 min walk - 0.2 miles
  • Fourth Street Live! - 8 min walk - 0.4 miles
  • Kentucky International Convention Center - 8 min walk - 0.5 miles
  • KFC Yum Center - 8 min walk - 0.5 miles

Getting around

  • Louisville Intl. Airport (SDF) - 10 min drive

Restaurants

  • ‪Thelma's Deli - ‬8 min walk
  • ‪Swizzle Dinner & Drinks - ‬8 min walk
  • ‪Bluegrass Brewing Company - ‬8 min walk
  • ‪Evan Williams Bourbon Experience - ‬3 min walk
  • ‪Jockey Silks Bourbon Bar - ‬7 min walk

About this property

21c Museum Hotel Louisville

Luxury hotel with a full-service spa and a 24-hour fitness center
Guests staying at 21c Museum Hotel Louisville enjoy access to a full-service spa, a 24-hour gym, and free WiFi in public areas. Valet parking is available for USD 32 per night, and there's also limo/town car service. The front desk has multilingual staff on hand 24/7 to help with luggage storage, dry cleaning/laundry, and tours or tickets. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this luxury hotel include meeting rooms, conference space, and a 24-hour business center.
50-inch LCD TVs come with cable channels, and guests can stay connected with free WiFi and wired Internet. Beds are dressed in premium bedding and down comforters, and bathrooms offer hair dryers and designer toiletries. IPod docks, minibars, and espresso makers are also standard. Change of towels is available on request.
Recreational amenities at the hotel include a 24-hour fitness center.

The recreational activities listed below are available either on site or nearby; fees may apply.

Guests can pamper themselves with a trip to the onsite spa, which has 2 treatment rooms. Services include massages.

Awards and affiliations

Eco-Certified Property
This property participates in Green Key Global, a program that measures the property's impact on one or more of the following: environment, community, cultural-heritage, the local economy.
21c Museum Hotel Louisville is listed in the 2014 Condé Nast Traveler Gold List of the world's best places to stay.

Languages

English, German, Spanish

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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transportation

  • Electric car charging station on site
  • Limo/town car service
  • Valet parking on site (USD 32 per night; includes in/out privileges)
  • Wheelchair-accessible parking available

Food and drink

  • Daily full breakfast available for a fee: USD 5 to 25 per person
  • A bar/lounge
  • A restaurant
  • Coffee and tea in common areas

Restaurants on site

  • Proof on Main

Things to do

  • 24-hour gym
  • Full-service spa
  • Yoga classes

Family friendly

  • In-room crib
  • Laundry facilities
  • Rollaway/extra bed (surcharge)
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Free newspapers in lobby
  • Gift shop/newsstand
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Multilingual staff
  • Porter/bellhop
  • Tour and ticket assistance
  • Turndown service

Business services

  • 24-hour business center
  • 5,000 square feet of conference space
  • Computer station
  • Meeting rooms

Full-service spa

  • 2 treatment rooms
  • In-room massages

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Elevator
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible registration desk

More

  • 1 building
  • 4 floors
  • At least 80% lighting from LEDs
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • Built in 2006
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoking not allowed

Room amenities

Bedroom

  • Blackout drapes
  • Down comforter
  • Free crib
  • Hypo-allergenic bedding
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathrobes
  • Designer toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 50-inch LCD TV with premium cable channels
  • iPod dock

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service
  • Minibar

More

  • Air conditioning (climate-controlled)
  • Cleaning products are eco-friendly
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Soundproofed rooms
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4 PM; Check-in end time: midnight
Contactless check-in available
Minimum check-in age: 21

Check-out

Check-out before 11 AM
Contactless check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 40.00 per accommodation, per stay
  • Pet weight must not exceed 50 lbs per pet
  • Food and water bowls are available
  • Service animals exempt from fees

Children and extra beds

  • Rollaway/extra beds are available for USD 30.0 per night
  • Free cribs/infant beds are available

Property payment types

Important information

Fees

  • Service fee: USD 5.00 per accommodation, per stay

These are all of the charges provided to us by the property.

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Fee for full breakfast: approximately USD 5 to 25 per person
  • Valet parking fee: USD 32 per night (in/out privileges)
  • Pet fee: USD 40.00 per accommodation, per stay
  • Service animals are exempt from fees
  • Rollaway bed fee: USD 30.0 per night

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit, and window guards
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels)
  • Check-in: 4 PM
  • Check-out: 11 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day. Driving? This property offers valet parking (fees apply), along with a car charging station.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A credit card for incidental charges and a government-issued photo ID may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • The credit card used at check-in for incidentals must be in the name of the primary guest who made the reservation.
  • Onsite safety features include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit, and window guards.
  • This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels).

Additional information about polices, regulations, and more:

  • Reservations need to be made in advance for massage services. Contact the hotel at the phone number listed on your booking confirmation.
  • Connecting or adjoining rooms can be requested, but all rooms are subject to availability. Contact the property using the phone number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21c Hotel Louisville
21c Hotel Museum
21c Louisville Hotel
21c Museum
21c Museum Hotel
21c Museum Hotel Louisville
21c Museum Louisville
Louisville 21c Hotel
Louisville 21c Museum
Museum Hotel 21c
21c Museum Hotel Louisville MGallery
21c Museum Louisville MGallery
Hotel 21c Museum Hotel Louisville - MGallery Louisville
Louisville 21c Museum Hotel Louisville - MGallery Hotel
21c Museum Hotel Louisville - MGallery Louisville
Hotel 21c Museum Hotel Louisville - MGallery
21c Museum Hotel MGallery
21c Museum MGallery
21c Museum Hotel Louisville
21c Museum Louisville Mgallery
21c Museum Louisville
21c Museum Hotel Louisville Hotel
21c Museum Hotel Louisville MGallery
21c Museum Hotel Louisville Louisville
21c Museum Hotel Louisville Hotel Louisville

Frequently asked questions

Is a free cancellation option available at 21c Museum Hotel Louisville?

21c Museum Hotel Louisville provides free cancellation on certain room rates. For more details, review the cancellation policy on our site.

How much does it cost to stay at 21c Museum Hotel Louisville?

As of Jul 16, 2025, prices found for a 1-night stay for 2 adults at 21c Museum Hotel Louisville on Aug 14, 2025 start from $189.05, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What is there to do near 21c Museum Hotel Louisville?

This hotel is situated in Downtown Louisville, just steps from Louisville Slugger Museum, and within a 10-minute walk of KFC Yum Center and Fourth Street Live!. You'll also find Churchill Downs and L&N Federal Credit Union Stadium within a short drive.

Will I be able to park at 21c Museum Hotel Louisville?

Yes, valet parking is offered for USD 32 per night with in/out privileges. Accessible parking and electric car charging are also available for guests.

Is there a spa at 21c Museum Hotel Louisville?

There is a full-service spa available for guests to enjoy and services include massages.

Does 21c Museum Hotel Louisville have a casino at the property?

No, 21c Museum Hotel Louisville doesn't have a casino.

Will I find an indoor pool at 21c Museum Hotel Louisville?

No, there is no indoor pool at this hotel.

What amenities will couples enjoy at 21c Museum Hotel Louisville?

This boutique hotel offers many amenities for couples, including in-room massages as well as a bar and a restaurant.

Does 21c Museum Hotel Louisville have a hot tub?

No, there isn't a spa tub at this hotel.

Does 21c Museum Hotel Louisville have a restaurant that serves breakfast?

Yes, 21c Museum Hotel Louisville serves a full breakfast for a surcharge each morning at Proof on Main.

Will 21c Museum Hotel Louisville allow pets to stay free of charge?

Although they can't stay for free, pets are welcome at 21c Museum Hotel Louisville for a fee of USD 40.00 per accommodation, per stay. The property also provides food and water bowls.

Are there connecting rooms at 21c Museum Hotel Louisville?

Yes, this hotel has connecting guestrooms you can book for your group event or vacation.

How far is the airport from 21c Museum Hotel Louisville?

The closest major airport to 21c Museum Hotel Louisville is Louisville Intl. Airport (SDF), which is 7.1 mi away (10 minutes by car). Another top airport is Louisville, KY (LOU-Bowman Field), which is located 8.1 mi away (11-minute drive).

Are there rooms with balconies that I can book at 21c Museum Hotel Louisville?

Yes, some guestrooms at 21c Museum Hotel Louisville offer a furnished balcony.

21c Museum Hotel Louisville Reviews

Reviews

9.2

Wonderful

Rating 10 - Excellent. 760 out of 1000 reviews
Rating 8 - Good. 138 out of 1000 reviews
Rating 6 - Okay. 59 out of 1000 reviews
Rating 4 - Poor. 24 out of 1000 reviews
Rating 2 - Terrible. 19 out of 1000 reviews

9.6/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

8/10 Good

Danielle

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great spot. The smell when you walk into the building is intense but the bar downstairs and the room were great
Stayed 2 nights in Jun 2025

10/10 Excellent

Jeffrey

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in May 2025

10/10 Excellent

Laura

Liked: Cleanliness, staff & service, property conditions & facilities
If you love modern art and a bit of whimsy on top of comfortable beds and a fantastic bathroom, you’ll love 21c!
Stayed 1 night in Apr 2025

10/10 Excellent

Elayne, Toronto

Traveled with partner
Liked: Cleanliness, staff & service, amenities
Amazing combination of art and hospitality. Great ambiance, staff, food. Large & quiet rooms, nice amenities with respect for the environment. Good gym, good downtown location close to museums and highways. I’ll return here again & try this chain in other cities. Highly recommend it.
Stayed 4 nights in Apr 2025

6/10 Okay

PIERRETTE

Traveled with group
Liked: Staff & service
Access to the museum was the amenity I appreciated. Customer service was good. Southern hospitality showed. However the mattresses are extremely firm and the water in the shower was not hot. There was also an escalated price for Saturday evening due to a city event. That city event was canceled prior to our stay and the cost per night was not changed. Also that weekend nightly rate makes no sense for a hotel without a pool.
Stayed 2 nights in Apr 2025

10/10 Excellent

Carol

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very fun Hotel with a really nice sub art and Exhibits and great location for walking the Louisville downtown. We definitely recommend staying here and we will stay here again.
Stayed 2 nights in Apr 2025

10/10 Excellent

Andrew

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Apr 2025

10/10 Excellent

Melanie

Liked: Cleanliness, staff & service, property conditions & facilities
Hip hotel with excellent restaurant and some wild art.
Stayed 2 nights in Feb 2025

10/10 Excellent

Beth

Liked: Cleanliness, staff & service, property conditions & facilities
This was an amazing and unique upscale hotel. We enjoyed our stay!
Stayed 1 night in Apr 2025

10/10 Excellent

John

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great vibe

Such a cool place. Great vibe
Stayed 3 nights in Apr 2025

10/10 Excellent

Eric

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Artsy Hotel

Love the art museum portion that makes this hotel unique! The room was big enough and has nice details like brick wall on one side of the room and black light lit bathroom. They even offer a free bourbon nightcap. They also have their own private select bourbon bottles for sale, but keep in mind they aren’t open for sale earlier in the morning.
Stayed 1 night in Mar 2025

10/10 Excellent

Teresa

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Enjoyed
Stayed 1 night in Mar 2025

10/10 Excellent

Thomas

Liked: Cleanliness, staff & service, property conditions & facilities
First time at a 21c Museum Hotel. Was a great experience.
Stayed 2 nights in Apr 2025

10/10 Excellent

Jessica

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great hotel to stay near plenty to do. Clean, comfortable, friendly staff!
Stayed 2 nights in Mar 2025

10/10 Excellent

Jackaline

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved everything about this hotel! The Art was amazing, staff were super friendly, restaurant had amazing food & the bar was great! Would stay there again, for sure!
Stayed 3 nights in Mar 2025

10/10 Excellent

Mario

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Mar 2025

10/10 Excellent

Sophia

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

10/10 Excellent

Leanna

Stayed 3 nights in Mar 2025

8/10 Good

Roni

Traveled with family
Liked: Cleanliness, amenities, property conditions & facilities
Very clean. Staff wasnt personable except in bar.
Stayed 1 night in Mar 2025

6/10 Okay

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities
Disliked: Room comfort

The hotel was nice, staff was great. But the bed w

The hotel was nice, staff were nice. But the bed was extremely uncomfortable and the room was stuffy and hot no matter what was done to the thermostat. If you like a firm mattress then you will like it
Stayed 1 night in Mar 2025

10/10 Excellent

stacy

Liked: Amenities
Great hotel
Stayed 1 night in Mar 2025

8/10 Good

Zachary

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

8/10 Good

Verified traveler

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Mar 2025

10/10 Excellent

Diane

Stayed 1 night in Mar 2025

10/10 Excellent

Rebecca

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful property, friendly staff, great food and drinks! And.....an art gallery! Perfect night in.
Stayed 1 night in Feb 2025

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