$47 Cheap flights to Jefferson County
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Top places to visit in Jefferson County
Cheap flights to Jefferson County from $47 One Way, $78 Round Trip
$78 return flights and $47 one-way flights to Jefferson County were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
| Origin | Destination | Travel Dates | Flights From* |
|---|---|---|---|
| PIE | Mascoutah | September 25 to September 30 | $283 |
| DEN | St. Louis | September 26 to October 5 | $329 |
| TTN | St. Louis | September 27 to October 2 | $345 |
| ATL | St. Louis | September 25 to September 25 | $370 |
| DFW | St. Louis | September 25 to October 4 | $409 |
| SEA | St. Louis | September 27 to October 10 | $446 |
| LAX | St. Louis | September 26 to September 28 | $457 |
| LGA | St. Louis | September 26 to September 29 | $473 |
| LGA | St. Louis | September 26 to September 29 | $473 |
| TPA | St. Louis | September 25 to September 27 | $510 |
Find The Perfect Hotel For After Your Flight
Score Epic Jefferson County Accommodation Deals
Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch
"Clean. All personnel effective, friendly, and efficient."
Reviewed on Sep 19, 2026
Pear Tree Inn St. Louis Airport
"Fantastic hotel! First and foremost the employees are so helpful and so kind, literally every one of them!! If you arrive at the airport and need the shuttle service—be sure to call to get them on their way! And likewise if you need a shuttle ride to the airport make sure to ask what time to be in ..."
Reviewed on Sep 19, 2026
Renaissance St. Louis Airport Hotel
Need a Car For After Your Flight?
Compact
$151
Economy
$151
Midsize SUV
$156
Special
$163
Jefferson County
Snag some “suite” deals when you add cheap hotel rooms to Jefferson County flights at Orbitz. You can score tickets to ballgames, concerts and other activities while planning your low fare flights. For non-stop air tickets or planned layovers, Orbitz is your discount travel resource.
Budget Prices, Luxury Life
Find mobile-only bargains on your home away from home with Orbitz cutting-edge mobile tools. Search domestic and international hotels at Orbitz On the Go. Find free travel planning apps for your iPhone, Android or iPad. You’ll always get our guaranteed low prices on your favorite hotels and flights to Jefferson County.
Fun for All
While shopping Orbitz sales on Jefferson County flights, remember to throw in some fun. Ticket sales for music, theatre, sports and more can be found on the Activities page. Just tell us what you want to do, and Orbitz will save your seat.
Non-Stop or Stop and Visit
Will you be flying round-trip or one-way? Going directly from Point A to Point B? Maybe you’d like to have dinner with family and friends along the way. Whether you need non-stop flights to {destination.name} or lowest cost layovers on Jefferson County flights, you will always find the best air travel prices at Orbitz.
All in One
Now you can custom design the perfect travel package with Orbitz and save more when booking your flights to Jefferson County. Do you have a favorite airline, hotel or car rental company? Every page at Orbitz gives you complete freedom to create your travel plans according to your unique wants and needs. Orbitz is designed to meet your discount travel planning needs completely and conveniently.
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.