COVID-19 alert: Travel requirements are changing rapidly, including need for pre-travel COVID-19 testing and quarantine on arrival.

Destin Vacation Homes

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Featured Vacation Homes in Destin

Don't see what you're looking for?
See all available properties in Destin
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Destin Vacation Homes

Book vacation homes in Destin
Next time you take a group getaway top Destin, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Destin vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Destin vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Destin; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Destin rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Destin is sure to be a winner.

Hotel Options in Destin

    SummerPlace Inn Destin
    SummerPlace Inn Destin
    14047 Emerald Coast Pkwy, Destin, FL
    The price is $115 per night from Mar 3 to Mar 4
    4.4/5Wonderful! (43 reviews)
    SummerPlace Inn Destin
    Home2 Suites By Hilton Destin
    Home2 Suites By Hilton Destin
    14060 Emerald Coast Pkwy, Destin, FL
    The price is $149 per night from Mar 1 to Mar 2
    4.6/5Wonderful! (26 reviews)
    Home2 Suites By Hilton Destin
    The Henderson, a Salamander Beach & Spa Resort
    The Henderson, a Salamander Beach & Spa Resort
    200 Henderson Resort Way, Destin, FL
    The price is $275 per night from Mar 1 to Mar 2
    4.5/5Wonderful! (27 reviews)
    The Henderson, a Salamander Beach & Spa Resort