
Cheap flights To Defiance (STL) from $29
Earn rewards on top of your airline miles with Orbitz Rewards
Many airlines offer flexible change policies
Sign up to receive text alerts about your trip
Cheap Flights to Defiance from $29 One Way, $59 Round Trip
Prices found within past 7 days. Prices and availability subject to change. Additional terms may apply.
Defiance Flight Information
Traveling To | Defiance |
|---|---|
Destination Airport IATA Code | STL |
Number of Airlines Serving | |
Airlines | Frontier Airlines, American Airlines, Southwest Airlines |
Flight Price | $59 |
Earliest Departing Flight | |
Latest Departing Flight |
Book Your Flight & Hotel Together & Save
- Economy Flight + Hotel Deals
- Premium Economy Flight + Hotel Deals
- Business Class Flight + Hotel Deals
- First Class Flight + Hotel Deals
Defiance economy flight packages



Defiance premium economy flight packages

Hampton Inn By Hilton St Louis Airport
Feb 8 - Feb 11
Phoenix (PHX) to St. Louis (STL)
Reviewed on Oct 26, 2025

Hilton St. Louis Airport
Feb 8 - Feb 11
Phoenix (PHX) to St. Louis (STL)
Reviewed on Dec 30, 2024

DoubleTree by Hilton St. Louis - Westport
Feb 8 - Feb 11
Phoenix (PHX) to St. Louis (STL)
Reviewed on Sep 3, 2025
Defiance
Reach your destination without breaking your budget by booking your flights to Defiance using Orbitz. We offer access to all of the best discounts on airfare, travel accommodations and even car rentals. Planning your trip and saving money are easier with Orbitz.
Get Discount Rates On Your Defiance Flight
Whether planning ahead or deciding to book your trip at the last minute, Orbitz will provide the lowest rates on Defiance flights. Using our free mobile phone apps will make you privy to a number of discounts that are unique to mobile phone users. These are perfect for harried travelers who want to find deals that they can qualify for on the same day.
Make Orbitz Your Official Travel Planner
Orbitz can be used for much more than comparing and booking a discount flight to Defiance. We also offer a variety of resources for securing the ideal travel accommodations while staying on budget. Travel tips, hotel reviews, customized suggestions and even detailed images can all be accessed through your mobile phone.
Build A Comprehensive Travel Itinerary
In addition to booking a low cost flight to Defiance, you can learn about the best places to visit, the best hotels to stay in and the preferred times for traveling. When you use Orbitz mobile phone apps you can also share your travel itineraries with friends and family members, all with just a few quick taps.
Using Orbitz to secure your Defiance flights can save you money and time. Perfect for both the early travel planner and the last minute journey: Orbitz offers phenomenal customer service and unbeatable convenience.
.
More to Explore
More to Explore
- 5 Star Hotels in Weldon Spring Heights
- Cabin Rentals in Weldon Spring Heights
- Condo Rentals in Weldon Spring Heights
- Extended Stay Hotels in Weldon Spring Heights
- Cheap Hotels in Weldon Spring Heights
- Weldon Spring Heights Hotels
- Vacation Homes in Weldon Spring Heights
- Resorts in Weldon Spring Heights
- Hotels near Historic Daniel Boone Home and Heritage Center
- Hotels near Six Flags St. Louis
- Hotels near Chesterfield Sports Fusion
- Hotels near Chandler Hill Vineyards
- 5 Star Hotels in New Melle
- Apartments in New Melle
- B&B in New Melle
- Cabin Rentals in New Melle
- Condo Rentals in New Melle
- 4 Star Hotels in Saint Albans
- Apartments in Saint Albans
- Chalets in Saint Albans
- Cottages in Saint Albans
- Guest Houses in Saint Albans
- Hotels near Babler State Park
- Guest Houses in Hamburg
- Lodges in Hamburg
- Hotels near Sugar Creek Winery
- Hotels near 9-11 Memorial
- Hotels near Spirit of St. Louis
- Hotels near Montelle Winery
- Hotels near Missouri Bluffs Golf Course
- Hotels near Broemmelsiek Park
- Hotels near Dr. Edmund A. Babler Memorial State Park
- Hotels near August A. Busch Memorial Conservation Area
- Cabin Rentals in Labadie
- Cottages in Labadie
- Extended Stay Hotels in Labadie
- Guest Houses in Labadie
- Labadie Hotels
- Vacation Homes in Labadie
- Villas in Labadie
- Hotels near St. Louis Premium Outlets
- Apartments in Augusta
- Guest Houses in Augusta
- Drury Inn & Suites Hotels in Augusta
- Romantic Getaways & Hotels in Augusta
- Spa Resorts & in Augusta
- Apartments in Grover
- Business Hotels in Grover
- Luxury Hotels in Grover
- Cabin Rentals in Wildwood
- Extended Stay Hotels in Wildwood
- Cheap Hotels in Wildwood
- Pet Friendly Hotels in Wildwood
- Villas in Wildwood
- 5 Star Hotels in Weldon Spring
- Flights to High Hill
- Flights to Earth City
- Flights to Sullivan
- Flights to Foristell
- Flights to Kingdom City
- Flights to Webster Groves
- Flights to Bowling Green
- Flights to Missouri
- Flights to Chesterfield
- Flights to Eureka
- Flights to De Soto
- Flights to St. Clair
- Flights to Louisiana
- Flights to Hermann
- Flights to Frontenac
- Flights to Cuba
- Flights to St. Charles
- Flights to Troy
- Flights to St. Peters
- Flights to St. Louis
- Flights to Union
- Flights to Florissant
- Flights to Rolla
- Flights to Warrenton
- Flights to Maryland Heights
- Flights to O'Fallon
- Flights from Grover
- Flights to Kirkwood
- Flights to Desloge
- Flights to Belleview
- Flights to Wildwood
- Flights from Montreal to Wildwood
- Flights from New York to Wildwood
- Flights from Orlando to Wildwood
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.
