Business Hotels in Cape Girardeau, MO
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Featured Cape Girardeau Business Hotels

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street, Cape Girardeau, MO
Free Cancellation
$103 nightly
The price is $116 total per night
$116 total
Aug 17 - Aug 18
Total includes taxes and fees
At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, guests enjoy a full-service spa, an indoor pool, and a gym. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Other amenities at this spa hotel include free WiFi in public areas, conference space, and a business center.
Pool
Breakfast included

Drury Inn & Suites Cape Girardeau
3303 Campster Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $102 total per night
$102 total
Aug 4 - Aug 5
Total includes taxes and fees
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$70 nightly
The price is $79 total per night
$79 total
Jul 31 - Aug 1
Total includes taxes and fees
Guests of Pear Tree Inn Cape Girardeau West enjoy a gym, free WiFi in public areas, and a 24-hour business center. You can put free parking to good use if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. This smoke-free hotel also has a TV in a common area.
Breakfast included
Pet friendly

Quality Inn
2011 North Kingshighway, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$60 nightly
The price is $68 total per night
$68 total
Aug 6 - Aug 7
Total includes taxes and fees
Guests of Quality Inn enjoy features like an outdoor pool, free WiFi in public areas, and a computer station. If you decide to drive, there's free parking. The 24-hour front desk has staff always at the ready. Additional amenities include laundry facilities, a TV in a common area, and a vending machine.
Pool
Breakfast included

Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd, Cape Girardeau, MO
Free Cancellation
$78 nightly
The price is $93 total per night
$93 total
Aug 24 - Aug 25
Total includes taxes and fees
At Candlewood Suites Cape Girardeau by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include meeting rooms, a business center, and free newspapers.
Pool
Pet friendly

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $102 total per night
$102 total
Aug 3 - Aug 4
Total includes taxes and fees
At Drury Plaza Hotel Cape Girardeau Conference Center, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a conference center.
Pool
Hot Tub

Hampton Inn Cape Girardeau I 55 East
207 S Mt Auburn Rd, Cape Girardeau, MO
Free Cancellation
Reserve now, pay when you stay
$110 nightly
The price is $124 total per night
$124 total
Aug 10 - Aug 11
Total includes taxes and fees
At Hampton Inn Cape Girardeau I 55 East, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with dry cleaning/laundry, securing valuables, and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cape Girardeau hotels essential information
Accommodation | 161 hotels |
---|---|
Lowest Price | $68 |
Highest Price | $124 |
Popular hotels | Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG, Drury Inn & Suites Cape Girardeau, Pear Tree Inn Cape Girardeau West, Quality Inn, Candlewood Suites Cape Girardeau by IHG, Drury Plaza Hotel Cape Girardeau Conference Center, Hampton Inn Cape Girardeau I 55 East |
Recent Business Hotels Reviews

Pear Tree Inn Cape Girardeau Near the Medical Center
5/5 Excellent
Super Facility Near The Medical Center!
"I have stayed at this Hotel several times when I have had early morning reporting times at St. Francis Medical Center. Each time it has been great. Friendly staff quiet atmosphere and great rooms with comfortable furnishings."
A verified traveler stayed at Pear Tree Inn Cape Girardeau Near the Medical Center
Posted 2 days ago
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