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Comfort Inn & Suites Sikeston I-55

2.5 star property
Hotel in Sikeston with a fitness center and a 24-hour front desk

Choose dates to view prices

Photo gallery for Comfort Inn & Suites Sikeston I-55

Exterior
Indoor pool
Desk, free WiFi, bed sheets, alarm clocks
Breakfast area
Lobby

Reviews

8.4 out of 10
Very good

Popular amenities

  • Gym
  • Laundry
  • Pet friendly
  • Parking included
  • Free WiFi

Explore the area

Map
109 Matthews Ln, Sikeston, MO, 63801
  • City of Miner Convention Center
    ‪5 min walk‬
  • The Book Bug
    ‪6 min walk‬
  • Sikeston Depot Museum
    ‪6 min drive‬
  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪31 min drive‬

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Room options

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking | Desk, free WiFi, bed sheets, alarm clocks

Suite, 1 King Bed with Sofa bed, Non Smoking

  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Standard Room, 2 Queen Beds, Non Smoking

Desk, free WiFi, bed sheets, alarm clocks

Standard Room, 2 Queen Beds, Non Smoking

  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

Desk, free WiFi, bed sheets, alarm clocks

Room, 2 Queen Beds, Accessible, Non Smoking

  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 1 King Bed, Accessible, Non Smoking

Desk, free WiFi, bed sheets, alarm clocks

Room, 1 King Bed, Accessible, Non Smoking

  • Sleeps 2
  • 1 King Bed

View all photos for Standard Room, 1 King Bed, Non Smoking

Desk, free WiFi, bed sheets, alarm clocks

Standard Room, 1 King Bed, Non Smoking

  • Sleeps 2
  • 1 King Bed

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About the neighborhood

Sikeston

Comfort Inn & Suites Sikeston I-55 places you next to The Book Bug and within a 10-minute walk of City of Miner Convention Center. This 64-room hotel welcomes guests with conveniences like an indoor pool, free in-room WiFi, and free self parking.

What's nearby

  • City of Miner Convention Center - 5 min walk - 0.3 miles
  • The Book Bug - 6 min walk - 0.4 miles
  • Central Park - 5 min drive - 3.5 miles
  • Sikeston Depot Museum - 6 min drive - 3.5 miles
  • Boot Heel Golf Club - 7 min drive - 3.3 miles

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 29 min drive

Restaurants

  • ‪Lambert's Caf - ‬17 min walk
  • ‪Taco Bell - ‬6 min drive
  • ‪Buffalo Wild Wings - ‬5 min drive
  • ‪Jay's Krispy Fried Chicken - ‬5 min drive
  • ‪McDonald's - ‬3 min walk

About this property

Comfort Inn & Suites Sikeston I-55

Hotel in Sikeston with a fitness center and a 24-hour front desk
At Comfort Inn & Suites Sikeston I-55, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a business center and laundry facilities.
Guests can expect to find free WiFi. Other amenities include coffee makers, phones, and desks.
Recreational amenities at the hotel include an indoor pool and a fitness center.

Languages

English, Hindi

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  • Breakfast included
  • Pet friendly
9.4 out of 10, Exceptional, 1,002 reviews
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The price is $103
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Total includes taxes and fees
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transportation

  • Free self parking on site
  • Wheelchair-accessible parking available

Things to do

  • Gym
  • Indoor pool

Family friendly

  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Safe at front desk

Business services

  • Business center

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Elevator
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible registration desk

More

  • 3 floors
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Bathtub or shower
  • Private bathroom
  • Towels provided

Entertainment

  • Cable/satellite channels

Food and drink

  • Coffee/tea maker

More

  • Air conditioning
  • Desk
  • Phone

Policies

Check-in

Check-in start time: 2:00 PM; Check-in end time: anytime
Minimum check-in age: 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • This property welcomes pets for USD 20 per pet, per night
  • Dogs and cats only
  • 2 total (20 lbs is the maximum weight per pet)
  • Certain rooms only
  • Guests can request a pet-friendly room by contacting the property at the number on the booking confirmation
  • Service animals exempt from fees

Property payment types

Important information

Optional extras

These fees and deposits will be charged at check-in, check-out, or the time of service.

  • Pet fee: USD 20 per pet, per night
  • Service animals are exempt from fees

This list may not be comprehensive. Fees and deposits might not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
  • Check-in: 2:00 PM
  • Check-out: 11:00 AM
  • Minimum check-in age: 21
The front desk is open 24 hours a day. Driving? This property offers free parking.

We should mention

Details about charges, deposits, or other important information:

  • This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
  • Charges for extra guests may apply and vary depending on the property's policy.
  • A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
  • Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
  • This property accepts credit cards. Cash is not accepted. 
  • This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice).

Additional information about polices, regulations, and more:

  • No cribs or infant beds are available.
  • No rollaway or extra beds are available.

Property is also known as

Comfort Inn Sikeston Hotel
Comfort Inn Sikeston

Frequently asked questions

Is free cancellation available at Comfort Inn & Suites Sikeston I-55?

Comfort Inn & Suites Sikeston I-55 provides free cancellation on some room rates. For additional details, look at the cancellation policy on our site.

How much does it cost to stay at Comfort Inn & Suites Sikeston I-55?

As of Jun 12, 2025, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Sikeston I-55 on Jun 15, 2025 start from $89.1, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

What's there to do close to Comfort Inn & Suites Sikeston I-55?

This hotel is located in Sikeston, just steps from The Book Bug. You'll also find Sikeston Depot Museum and Boot Heel Golf Club within a short drive.

Is parking available on site at Comfort Inn & Suites Sikeston I-55?

Yes, self parking is offered for free at the hotel. Accessible parking is also available for guests.

Does Comfort Inn & Suites Sikeston I-55 have a casino?

No, Comfort Inn & Suites Sikeston I-55 doesn't have a casino.

Is there an indoor pool at Comfort Inn & Suites Sikeston I-55?

Yes, this hotel has an indoor pool.

What will couples enjoy most about a stay at Comfort Inn & Suites Sikeston I-55?

Amenities at this hotel that appeal to couples include an indoor pool and a 24-hour front desk.

Are there hot tubs at Comfort Inn & Suites Sikeston I-55?

No, this hotel doesn't have a spa tub.

Does Comfort Inn & Suites Sikeston I-55 have a restaurant that serves breakfast?

No, Comfort Inn & Suites Sikeston I-55 doesn't have a restaurant that serves breakfast.

Does Comfort Inn & Suites Sikeston I-55 allow pets to stay for free?

Although they can't stay for free, cats and dogs are welcome at Comfort Inn & Suites Sikeston I-55 for a fee of USD 20 per pet, per night.

Are there connecting rooms at Comfort Inn & Suites Sikeston I-55?

No, this hotel doesn't feature connecting guestrooms.

How far is the airport from Comfort Inn & Suites Sikeston I-55?

The closest major airport to Comfort Inn & Suites Sikeston I-55 is Cairo, IL (CIR-Cairo Regional), which is 28.1 mi away (29 minutes by car). Another top airport is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), which is located 26.7 mi away (29-minute drive).

Can I book a room with a balcony at Comfort Inn & Suites Sikeston I-55?

No, you won't find guestrooms with balconies at Comfort Inn & Suites Sikeston I-55.

Comfort Inn & Suites Sikeston I-55 Reviews

Reviews

8.4

Very Good

Rating 10 - Excellent. 121 out of 260 reviews
Rating 8 - Good. 88 out of 260 reviews
Rating 6 - Okay. 26 out of 260 reviews
Rating 4 - Poor. 17 out of 260 reviews
Rating 2 - Terrible. 8 out of 260 reviews

8.4/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.2/10

Property conditions & facilities

8.2/10

Eco-friendliness

Reviews

10/10 Excellent

Becky

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Mar 2025

8/10 Good

Denise

Business traveler
hotel was fine clean and convient
Stayed 1 night in Feb 2025

8/10 Good

Walter

Liked: Cleanliness, staff & service, property conditions & facilities
Good place to spend a night
Stayed 1 night in Mar 2025

10/10 Excellent

Debra

Traveled with group, Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Feb 2025

10/10 Excellent

Margaret

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Thank you

Great stay, quiet, friendly and just what we expected!
Stayed 1 night in Feb 2025

10/10 Excellent

Mike

Traveled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, and available rooms when we needed it most due to storms
Stayed 1 night in Feb 2025

10/10 Excellent

Diane

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice helpful young man checked us in. And help with our TV connection!
Stayed 1 night in Feb 2025

10/10 Excellent

George

Business traveler
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Roger

Traveled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice spacious rooms. Beds were very comfortable. Quiet place.
Stayed 1 night in Jan 2025

10/10 Excellent

Ruth Ann

Stayed 1 night in Sep 2024

8/10 Good

Tamra

Liked: Cleanliness, staff & service, property conditions & facilities
Needs diet soda option in the vending machine
Stayed 1 night in Dec 2024

10/10 Excellent

Michael, Chicago

Liked: Cleanliness, staff & service, property conditions & facilities
Conveniant to I55, clean, and comfortable,
Stayed 1 night in Dec 2024

4/10 Poor

Sheldon

Disliked: Property conditions & facilities, room comfort

Poor night of sleep

Very poor bedding the mattress needs replacement Angry cleaning people yelling at each other at a very loudly voice and in need of over do total complete renovation
Stayed 1 night in Dec 2024

8/10 Good

Verified traveler

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Just one night

We were in town for a funeral and to visit family. We were only at the hotel for a place to sleep. It was comfortable, quiet, and clean. Plus, it was very affordable.
Stayed 1 night in Nov 2024

8/10 Good

terrence

Stayed 2 nights in Nov 2024

8/10 Good

GEORGE

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Nov 2024

10/10 Excellent

Mary

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Very enjoyable
Stayed 1 night in Oct 2024

8/10 Good

Sherry

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Quick trip

Just stayed 1 night before st louis. Perfect for what we needed.I would stay again
Stayed 1 night in Oct 2024

10/10 Excellent

Sasha

Traveled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We were happy with our stay
Stayed 1 night in Oct 2024

8/10 Good

Katherine, Denham Springs

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities
This place was very nice. I couldn’t give it 5 stars as the check in desk gave our room to another guest along with the key. Boy was I surprised when a stranger opened my door! It got straightened out but then our key no longer worked. Was a hassle running to the front desk so much
Stayed 1 night in Oct 2024

10/10 Excellent

Mark, Austin

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room carpet could use changing, but otherwise clean, quiet, feiendly staff, and a great morning breakfast.
Stayed 1 night in Sep 2024

10/10 Excellent

Drew

Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfect Pit Stop

Check in was easy with friendly staff. Hotel had everything you would need, plus walking distance to dining.
Stayed 1 night in Sep 2024

8/10 Good

Doug

Traveled with family
Liked: Cleanliness, staff & service
Property could use some upgrades and deep cleaning.
Stayed 2 nights in Sep 2024

8/10 Good

Felicia

Traveled with group, Traveled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Aug 2024

4/10 Poor

Alex

Disliked: Cleanliness, property conditions & facilities
dirty the rooms were not cleaned properly
Stayed 1 night in Sep 2024

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