Book 2 Star Hotels in Sikeston
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Featured Sikeston 2 Stars Hotels

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
3.13 mi from city center
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included

Best Western Plus Sikeston
120 S Interstate Drive, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
3.35 mi from city center
Guests of Best Western Plus Sikeston have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a computer station, and express check-out.
Pool
Breakfast included

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
3.34 mi from city center
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a banquet hall.
Breakfast included
Pet friendly

Pear Tree Inn Sikeston
2602 E Malone Avenue, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
3.06 mi from city center
Pear Tree Inn Sikeston features an indoor pool, an outdoor pool, and a gym. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include free WiFi in public areas, a hot tub, and a business center.
Pool
Hot Tub

Hampton Inn Sikeston
1240 Commerce Drive, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
1.46 mi from city center
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr, Sikeston, MO
1.41 mi from city center
Guests staying at Holiday Inn Express & Suites Sikeston Southwest by IHG enjoy an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Country Yard Inn and Suite
110 South Interstate Drive, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
3.42 mi from city center
At Country Yard Inn and Suite, guests have access to free WiFi in public areas. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready.
Pet friendly
Parking included

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
2.87 mi from city center
Guests staying at Super 8 by Wyndham Sikeston/Miner Area enjoy free WiFi in public areas, a library, and a vending machine. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests.
Breakfast included
Pet friendly

Comfort Inn & Suites Sikeston I-55
109 Matthews Ln, Sikeston, MO
Free Cancellation
Reserve now, pay when you stay
3.04 mi from city center
At Comfort Inn & Suites Sikeston I-55, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a business center and laundry facilities.
Pool
Pet friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Sikeston hotels essential information
Accommodation | 267 hotels |
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Lowest Price | |
Highest Price | |
Popular hotels | Drury Inn & Suites Sikeston, MO, Best Western Plus Sikeston, Days Inn and Suites by Wyndham Sikeston, Pear Tree Inn Sikeston, Hampton Inn Sikeston, Holiday Inn Express & Suites Sikeston Southwest by IHG, Country Yard Inn and Suite, Super 8 by Wyndham Sikeston/Miner Area, Comfort Inn & Suites Sikeston I-55 |
Recent Reviews

Drury Inn & Suites Sikeston, MO
5/5 Excellent
"We got in late, but everything was great!! I wish the fountain machine would have been available when we arrived at 10:15pm. The room was nice and spacious, but the a/c was loud. The breakfast was great! We would definitely stay here again!! ❤️"
A verified traveler stayed at Drury Inn & Suites Sikeston, MO
Posted 3 days ago