There aren't any direct flights between these destinations. But American Airlines, Delta Air Lines and United Airlines can get you from Wilkes-Barre, PA Airport (AVP-Scranton Intl.) to San Diego, CA Airport (SAN-San Diego Intl.) with only one stopover.
The quickest flight time from Wilkes-Barre, PA Airport (AVP-Scranton Intl.) to San Diego, CA Airport (SAN-San Diego Intl.) is 5 hours and 59 minutes, which gives you more than enough time to indulge in a tipple or get absorbed in a good movie.
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|Destination Airport IATA Code||SAN|
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^Savings based on all package bookings with Flight + Hotel made on Orbitz.com from January 1, 2019 to December 31, 2019 as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.