Cheap flights from MDT to BRU (Harrisburg Intl. to Brussels - National)

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Cheap Flights from MDT to BRU starting at $466 One Way, $789 Round Trip

Prices starting at $789 for return flights and $466 for one-way flights to Brussels - National were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near Brussels - National

Airport Hotels near Brussels - National

Sheraton Brussels Airport Hotel

Sheraton Brussels Airport Hotel

4 out of 5
Brussels National Airport Zaventem
$151 nightly
The price is $173 total per night from Feb 28 to Mar 1
$173 total
Feb 28 - Mar 1
Total with taxes and fees
Book a stay at this business-friendly hotel in Zaventem. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,197 reviews)
Easy access to the airport

Reviewed on Feb 9, 2026

Sheraton Brussels Airport Hotel
Crowne Plaza Brussels Airport by IHG

Crowne Plaza Brussels Airport by IHG

4 out of 5
Da Vincilaan 4 Machelen
$128 nightly
The price is $148 total per night from Mar 13 to Mar 14
$148 total
Mar 13 - Mar 14
Total with taxes and fees
Book a stay at this business-friendly hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the restaurant ...
9/10 Wonderful! (872 reviews)
Excellent!!!

Reviewed on Jan 19, 2026

Crowne Plaza Brussels Airport by IHG
Van Der Valk Hotel Brussels Airport

Van Der Valk Hotel Brussels Airport

4 out of 5
Culliganlaan 4B Machelen
$95 nightly
The price is $108 total per night from Feb 22 to Feb 23
$108 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our ...
8.2/10 Very Good! (1,001 reviews)
Spotless room and amazing staff

Reviewed on Jan 1, 2026

Van Der Valk Hotel Brussels Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Brussels

The Hotel

The Hotel

4 out of 5
38 Boulevard de Waterloo Brussels
$171 nightly
The price is $188 total per night from Feb 19 to Feb 20
$188 total
Feb 19 - Feb 20
Total with taxes and fees
Book a stay at this luxury hotel in Brussels. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
9/10 Wonderful! (1,355 reviews)
Nice staff, The Lounge was great,

Reviewed on Feb 8, 2026

The Hotel
Hotel Le Dome

Hotel Le Dome

3 out of 5
Boulevard Du Jardin Botanique 9-12-13 Brussels
$95 nightly
The price is $108 total per night from Feb 15 to Feb 16
$108 total
Feb 15 - Feb 16
Total with taxes and fees
Stay at this hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (565 reviews)
Enjoyed our stay.

Reviewed on Dec 19, 2025

Hotel Le Dome
Warwick Grand-Place Brussels

Warwick Grand-Place Brussels

4 out of 5
Rue Duquesnoy 5-7 Brussels
$143 nightly
The price is $158 total per night from Mar 1 to Mar 2
$158 total
Mar 1 - Mar 2
Total with taxes and fees
Book a stay at this family-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,630 reviews)
Very nice room. Very clean. Comfortable bed. But free WiFi is very poor

Reviewed on Feb 12, 2026

Warwick Grand-Place Brussels
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Brussels Hotels With Airport Transportation

Novotel Brussels Airport

Novotel Brussels Airport

3.5 out of 5
Da vinci laan 25 Machelen Flemish Brabant
$80 nightly
The price is $91 total per night from Mar 6 to Mar 7
$91 total
Mar 6 - Mar 7
Total with taxes and fees
Book a stay at this family-friendly hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful staff ...
8.4/10 Very Good! (1,001 reviews)
Nice

Reviewed on Jan 20, 2026

Novotel Brussels Airport
ibis budget Brussels Airport

ibis budget Brussels Airport

1 out of 5
Bessenveldstraat Machelen
$50 nightly
The price is $59 total per night from Mar 1 to Mar 2
$59 total
Mar 1 - Mar 2
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
7.2/10 Good! (1,001 reviews)
Yes

Reviewed on Feb 12, 2026

ibis budget Brussels Airport
ibis Brussels Airport

ibis Brussels Airport

3 out of 5
Bessenveldstraat 17 Machelen
$63 nightly
The price is $73 total per night from Mar 6 to Mar 7
$73 total
Mar 6 - Mar 7
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the property condition in our reviews. Popular ...
7.2/10 Good! (764 reviews)
Nothing to share. Arrived late, left early.

Reviewed on Dec 10, 2025

ibis Brussels Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Brussels Hotels

easyHotel Brussels City Centre

easyHotel Brussels City Centre

3 out of 5
Zilverstraat 1 Brussels
$85 nightly
The price is $96 total per night from Mar 8 to Mar 9
$96 total
Mar 8 - Mar 9
Total with taxes and fees
Stay at this hotel in Brussels. Enjoy free WiFi, a 24-hour front desk, and a computer station. Our guests praise the helpful staff and the clean rooms in our ...
8.4/10 Very Good! (1,002 reviews)
Spacious and clean room. Quiet and nice location.

Reviewed on Feb 2, 2026

easyHotel Brussels City Centre
ibis budget Brussels Airport

ibis budget Brussels Airport

1 out of 5
Bessenveldstraat Machelen
$50 nightly
The price is $59 total per night from Mar 1 to Mar 2
$59 total
Mar 1 - Mar 2
Total with taxes and fees
Stay at this hotel in Machelen. Enjoy free WiFi, breakfast (surcharge), and parking (surcharge). Our guests praise the helpful staff and the clean rooms in our ...
7.2/10 Good! (1,001 reviews)
Yes

Reviewed on Feb 12, 2026

ibis budget Brussels Airport
Bedford Hotel & Congress Centre

Bedford Hotel & Congress Centre

3.5 out of 5
Rue Du Midi 135 Brussels
$105 nightly
The price is $117 total per night from Feb 26 to Feb 27
$117 total
Feb 26 - Feb 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and a fitness center. Our guests praise the breakfast and the ...
8.2/10 Very Good! (1,003 reviews)
Room was spotless, and bigger than expected. Everything was great, even breakfast.

Reviewed on Feb 4, 2026

Bedford Hotel & Congress Centre
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Brussels

Novotel Brussels City Centre

Novotel Brussels City Centre

4 out of 5
Rue De La Vierge Noire 32 Brussels
$129 nightly
The price is $143 total per night from Mar 8 to Mar 9
$143 total
Mar 8 - Mar 9
Total with taxes and fees
Book a stay at this business-friendly hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and 24-hour room service. Our guests praise the helpful staff ...
8.8/10 Excellent! (1,005 reviews)
Fantastic staff, great location and rooms

Reviewed on Feb 6, 2026

Novotel Brussels City Centre
Novotel Brussels off Grand'Place

Novotel Brussels off Grand'Place

4 out of 5
120 Rue Du Marche Aux Herbes Brussels
$144 nightly
The price is $159 total per night from Mar 1 to Mar 2
$159 total
Mar 1 - Mar 2
Total with taxes and fees
Stay at this hotel in Brussels. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,003 reviews)
Central location friendly staff

Reviewed on Jan 21, 2026

Novotel Brussels off Grand'Place
Meininger

Meininger

3 out of 5
33 Quai du Hainaut / Henegouwenkaai Brussels Brussels-Capital Region
Stay at this hotel in Brussels. Enjoy free WiFi, free parking, and breakfast (surcharge). Popular attractions La Grand Place and Brussels Christmas Market are ...
מלון זול יחסית, נוח למשפחות מיקום כ - 1 ק"מ ממרכז בריסל

Reviewed on Jul 29, 2021

Meininger
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

MDT to BRU Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What is the shortest flight from MDT to Brussels Airport?
With the quickest flight time from Harrisburg Intl. Airport (MDT) to Brussels - National Airport (BRU) being 9 hours and 20 minutes, it's smart to have some in-flight survival tricks up your sleeve. An eye-mask, a neck pillow and earplugs should be among the essentials you put in your hand luggage.
How many hours flight from Harrisburg Intl. Airport (MDT) to BRU?
The trip from MDT to Brussels Airport typically lasts about 9 hours and 21 minutes. Make this long-haul flight go by a little faster by bringing your laptop full of your favorite flicks.
What airlines have the most flights from Harrisburg Intl. Airport (MDT) to BRU?
Watch the planes take off and land, grab a glazed doughnut, stretch your legs … Airport stopovers don't have to be boring! If you're planning to head from Harrisburg Intl. Airport to Brussels Airport, you can't fly direct. Be prepared for at least one stopover somewhere.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.