Compare Upstate South Carolina Guest House Rentals

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Featured Guest Houses in Upstate South Carolina

✨ Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more.

✨ Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more.

Travelers Rest SC
At this guesthouse, guests have access to features like laundry facilities. This smoke-free guesthouse also has a garden.
Free WiFi
Air conditioning
Chauga River - The Guest House - Private - Secluded

Chauga River - The Guest House - Private - Secluded

Mountain Rest SC
At this guesthouse, guests have access to features like laundry facilities. This smoke-free guesthouse also has barbecue grills.
Air conditioning
Parking available
Private Suite in Downtown Simpsonville

Private Suite in Downtown Simpsonville

Simpsonville SC
At this guesthouse, guests have access to a garden.
Pet friendly
Air conditioning
Bright and beautiful Cottage near Spartanburg , Tryon Intl Eq Center, Asheville.

Bright and beautiful Cottage near Spartanburg , Tryon Intl Eq Center, Asheville.

Chesnee SC
At this guesthouse, guests have access to a garden.
Free WiFi
Air conditioning
Light and airy contemporary guest house with private deck and parking.

Light and airy contemporary guest house with private deck and parking.

Travelers Rest SC
Guests staying at this guesthouse have access to laundry facilities, barbecue grills, and a garden.
Air conditioning
Parking available
Peaceful Lakefront Getaway Close to Clemson

Peaceful Lakefront Getaway Close to Clemson

Townville SC
At this guesthouse, guests have access to an arcade/game room, laundry facilities, and barbecue grills.
Free WiFi
Air conditioning
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Upstate South Carolina

    Grand Bohemian Lodge Greenville, Autograph Collection

    Grand Bohemian Lodge Greenville, Autograph Collection

    44 EAST CAMPERDOWN WAY Greenville SC
    $236 nightly
    The price is $259 total per night from Feb 8 to Feb 9
    $259 total
    Feb 8 - Feb 9
    Total with taxes and fees
    9.4/10 Exceptional! (440 reviews)
    Hyatt Regency Greenville

    Hyatt Regency Greenville

    220 N Main St Greenville SC
    $149 nightly
    The price is $163 total per night from Feb 22 to Feb 23
    $163 total
    Feb 22 - Feb 23
    Total with taxes and fees
    8.6/10 Excellent! (1,000 reviews)
    Sleep Inn Spartanburg Southwest

    Sleep Inn Spartanburg Southwest

    501 South Blackstock Rd Spartanburg SC
    $62 nightly
    The price is $68 total per night from Mar 1 to Mar 2
    $68 total
    Mar 1 - Mar 2
    Total with taxes and fees
    5.8/10 (538 reviews)

Upstate South Carolina Guest Houses essential information

Accommodation
6 Guest Houses
Lowest Price
$68
Highest Price
$259
Popular accommodation
✨ Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more., Chauga River - The Guest House - Private - Secluded, Private Suite in Downtown Simpsonville, Bright and beautiful Cottage near Spartanburg , Tryon Intl Eq Center, Asheville., Light and airy contemporary guest house with private deck and parking., Peaceful Lakefront Getaway Close to Clemson

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