Hotels near Sikeston Depot Museum
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Check prices close to Sikeston Depot Museum for tomorrow night, Jul 3 - Jul 4Featured Hotels near Sikeston Depot Museum

Tranquil 2-bedroom apartment with AC in charming Sikeston Missouri
Sikeston MO
0.2 mi from Sikeston Depot Museum
At this apartment, guests have access to features like laundry facilities.
Washer
Dryer

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Free Cancellation
1.33 mi from Sikeston Depot Museum
$105 nightly
The price is $119 total per night
$119 total
Aug 2 - Aug 3
Total with taxes and fees
Guests staying at Holiday Inn Express & Suites Sikeston Southwest by IHG enjoy an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
1.45 mi from Sikeston Depot Museum
$102 nightly
The price is $116 total per night
$116 total
Jul 12 - Jul 13
Total with taxes and fees
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with luggage storage and securing valuables. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Breakfast included

TownePlace Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
1.45 mi from Sikeston Depot Museum
$109 nightly
The price is $123 total per night
$123 total
Jul 12 - Jul 13
Total with taxes and fees
Built in 2025, the brand new TownePlace Suites by Marriott Sikeston offers an indoor pool, a gym, and free WiFi in public areas. Free parking is included with your stay. The 24-hour front desk has multilingual staff ready to assist with securing valuables and concierge services. Additional amenities include a business center, coffee/tea in a common area, and a computer station.
Pool
Breakfast included

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
1.47 mi from Sikeston Depot Museum
$110 nightly
The price is $124 total per night
$124 total
Jul 12 - Jul 13
Total with taxes and fees
Built in 2025, the brand new Fairfield Inn & Suites by Marriott Sikeston offers an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include coffee/tea in a common area and laundry facilities.
Pool
Breakfast included

Super 8 by Wyndham Sikeston/Miner Area
2609 E Malone Ave Sikeston MO
Free Cancellation
Reserve now, pay when you stay
2.9 mi from Sikeston Depot Museum
$63 nightly
The price is $72 total per night
$72 total
Jul 26 - Jul 27
Total with taxes and fees
Guests staying at Super 8 by Wyndham Sikeston/Miner Area enjoy free WiFi in public areas, a library, and a vending machine. If you drive, take advantage of free parking. Front-desk staff are standing by 24/7 to assist with any requests.

Drury Inn & Suites Sikeston, MO
2608 East Malone Ave, Miner Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.16 mi from Sikeston Depot Museum
$111 nightly
The price is $128 total per night
$128 total
Jul 6 - Jul 7
Total with taxes and fees
Drury Inn & Suites Sikeston, MO features an indoor pool, an outdoor pool, and a gym. If you drive, put free parking to good use. The front desk is staffed 24/7 to help with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include free WiFi in public areas, meeting rooms, and a business center.
Pool
Breakfast included

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.37 mi from Sikeston Depot Museum
$69 nightly
The price is $78 total per night
$78 total
Jul 26 - Jul 27
Total with taxes and fees
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a banquet hall.
Breakfast included
Pet friendly

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
3.38 mi from Sikeston Depot Museum
$85 nightly
The price is $97 total per night
$97 total
Jul 26 - Jul 27
Total with taxes and fees
Guests of Best Western Plus Sikeston I-55 have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a computer station, and express check-out.
Pool
Breakfast included
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See all available properties in Sikeston Depot Museum
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Sikeston Depot Museum hotels essential information
Accommodation | 90 hotels |
|---|---|
Lowest Price | $72 |
Highest Price | $128 |
Popular hotels | Drury Inn & Suites Sikeston, MO, Days Inn and Suites by Wyndham Sikeston, Hampton Inn Sikeston, Holiday Inn Express & Suites Sikeston Southwest by IHG, Fairfield Inn & Suites by Marriott Sikeston, Best Western Plus Sikeston I-55, Tranquil 2-bedroom apartment with AC in charming Sikeston Missouri, TownePlace Suites by Marriott Sikeston, Super 8 by Wyndham Sikeston/Miner Area |
Recent Reviews

Fairfield Inn & Suites by Marriott Sikeston
4/5 Good
"Perfect last minute stop on our road trip Very clean, well maintained and pleasant staff"
A verified traveler stayed at Fairfield Inn & Suites by Marriott Sikeston
Posted 9 hours ago


