$401 Cheap flights to São Tomé and Príncipe

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Cheap flights to São Tomé and Príncipe from $401 One Way, $453 Round Trip

$453 return flights and $401 one-way flights to São Tomé and Príncipe were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Mar 5 - Sun, Mar 14
ACC
Accra
TMS
São Tomé Island
$453 Roundtrip, found 3 days ago
$453
Roundtrip
found 3 days ago
Select TAP Portugal flight, departing Fri, Mar 5 from Accra to São Tomé Island, returning Sun, Mar 14, priced at $453 found 3 days ago
Fri, May 21 - Sun, May 30
ACC
Accra
TMS
São Tomé Island
$478 Roundtrip, found 3 hours ago
$478
Roundtrip
found 3 hours ago
Select TAP Portugal flight, departing Fri, May 21 from Accra to São Tomé Island, returning Sun, May 30, priced at $478 found 3 hours ago
Sat, Feb 13 - Sun, Feb 21
LIS
Lisbon
TMS
São Tomé Island
$561 Roundtrip, found 1 day ago
$561
Roundtrip
found 1 day ago
Select TAAG Angola Airlines flight, departing Sat, Feb 13 from Lisbon to São Tomé Island, returning Sun, Feb 21, priced at $561 found 1 day ago
Tue, Feb 23 - Sun, Feb 28
DLA
Douala
TMS
São Tomé Island
$1,165 Roundtrip, just found
$1,165
Roundtrip
just found
Select Hahn Air Systems flight, departing Tue, Feb 23 from Douala to São Tomé Island, returning Sun, Feb 28, priced at $1,165 just found
Sun, Jul 11 - Wed, Jul 28
FRA
Frankfurt
TMS
São Tomé Island
$1,201 Roundtrip, found 1 day ago
$1,201
Roundtrip
found 1 day ago
Select TAAG Angola Airlines flight, departing Sun, Jul 11 from Frankfurt to São Tomé Island, returning Wed, Jul 28, priced at $1,201 found 1 day ago
Tue, Feb 23 - Sun, Feb 28
DLA
Douala
TMS
São Tomé Island
$1,227 Roundtrip, just found
$1,227
Roundtrip
just found
Select APG Distribution System flight, departing Tue, Feb 23 from Douala to São Tomé Island, returning Sun, Feb 28, priced at $1,227 just found
Mon, Mar 15 - Sat, Mar 20
BOS
Boston
TMS
São Tomé Island
$1,818 Roundtrip, found 3 days ago
$1,818
Roundtrip
found 3 days ago
Select Air Canada flight, departing Mon, Mar 15 from Boston to São Tomé Island, returning Sat, Mar 20, priced at $1,818 found 3 days ago
Mon, Mar 15 - Sat, Mar 20
BOS
Boston
TMS
São Tomé Island
$1,827 Roundtrip, found 3 days ago
$1,827
Roundtrip
found 3 days ago
Select Air Canada flight, departing Mon, Mar 15 from Boston to São Tomé Island, returning Sat, Mar 20, priced at $1,827 found 3 days ago
Mon, Mar 15 - Sat, Mar 20
BOS
Boston
TMS
São Tomé Island
$1,838 Roundtrip, found 3 days ago
$1,838
Roundtrip
found 3 days ago
Select Air Canada flight, departing Mon, Mar 15 from Boston to São Tomé Island, returning Sat, Mar 20, priced at $1,838 found 3 days ago
Mon, Mar 15 - Sat, Mar 20
BOS
Boston
TMS
São Tomé Island
$1,840 Roundtrip, found 3 days ago
$1,840
Roundtrip
found 3 days ago
Select Air Canada flight, departing Mon, Mar 15 from Boston to São Tomé Island, returning Sat, Mar 20, priced at $1,840 found 3 days ago
Mon, Mar 15 - Sat, Mar 20
BOS
Boston
TMS
São Tomé Island
$1,841 Roundtrip, found 3 days ago
$1,841
Roundtrip
found 3 days ago
Select Lufthansa flight, departing Mon, Mar 15 from Boston to São Tomé Island, returning Sat, Mar 20, priced at $1,841 found 3 days ago
Wed, Mar 10 - Wed, Mar 17
EWR
New York
TMS
São Tomé Island
$1,845 Roundtrip, found 5 days ago
$1,845
Roundtrip
found 5 days ago
Select Swiss International Air Lines flight, departing Wed, Mar 10 from New York to São Tomé Island, returning Wed, Mar 17, priced at $1,845 found 5 days ago
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Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
ACCSão ToméNovember 22 to November 29$525
LISSão ToméNovember 21 to November 28$936
JFKSão ToméNovember 20 to November 28$2,331
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Our Top São Tomé and Príncipe Apartment Hotels

Sweet Guest House

Sweet Guest House

2.5 out of 5
Vila Dolores n. 087 São Tomé
Book a stay at this spa guesthouse in São Tomé. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Cloçon Téla Chocolate Factory and ...
Get rates
Opens in a new windowSweet Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic São Tomé and Príncipe Accommodation Deals

Pestana São Tomé

Pestana São Tomé

5 out of 5
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
The price is $239 total per night from Nov 16 to Nov 17
$239 total
per night
Nov 16 - Nov 17
Book a stay at this luxury hotel in São Tomé. Enjoy free WiFi, free parking, and room service. Popular attractions Estadio Nacional 12 de Julho and Cloçon Téla ...
8.2/10 Very Good! (84 reviews)
"The location and pool were excellent; however, the gym was very mediocre with outdated machines and no other amenities besides the pool and sauna were available. Also, no beach access other than a trashy public beach near the hotel."

Reviewed on Nov 10, 2026

Opens in a new windowPestana São Tomé
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto São Tomé
The price is $218 total per night from Nov 16 to Nov 17
$218 total
per night
Nov 16 - Nov 17
Book a stay at this beach resort in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon Téla Chocolate ...
9.4/10 Exceptional! (69 reviews)
"Clean and beautiful grounds, but the customer service is lacking!"

Reviewed on Oct 9, 2026

Opens in a new windowOmali São Tomé – Principe Collection
Hotel Central

Hotel Central

3.5 out of 5
Rua de Angola São Tomé São Tomé
The price is $53 total per night from Nov 23 to Nov 24
$53 total
per night
Nov 23 - Nov 24
Book a stay at this business-friendly hotel in São Tomé. Enjoy free breakfast, free parking, and an airport shuttle (surcharge). Popular attractions Cloçon Téla ...
8/10 Very Good! (29 reviews)
"While the room, location and property were great. Staff lacks initiative, I asked why no one answered my emails about a airport transfer which is advertised that it can be arranged upon request, I was told that the person that usually handles emails and airport transfers is sick, hence no response. ..."

Reviewed on Oct 21, 2026

Opens in a new windowHotel Central
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Sundy Praia – Principe Collection

Sundy Praia – Principe Collection

5 out of 5
Praia Sundy Príncipe Island
The price is $790 total per night from Nov 16 to Nov 17
$790 total
per night
Nov 16 - Nov 17
Book a stay at this luxury hotel in Príncipe Island. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Margarida Beach and Sundy Plantation ...
Opens in a new windowSundy Praia – Principe Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in São Tomé and Príncipe

Bom Bom – Principe Collection

Bom Bom – Principe Collection

4 out of 5
Bom Bom Island Príncipe Island
$547 nightly
The price is $629 total per night from Nov 23 to Nov 24
$629 total
Nov 23 - Nov 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Príncipe Island. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Praia Santa Rita and Praia ...
Opens in a new windowBom Bom – Principe Collection
Somos Hotel Avenida

Somos Hotel Avenida

3 out of 5
Avenida da Independencia São Tomé São Tomé
Book a stay at this business-friendly hotel in São Tomé. Enjoy free breakfast, free parking, and room service. Popular attractions Estadio Nacional 12 de Julho ...
6.6/10 (4 reviews)
Good
"Good"

Reviewed on Aug 29, 2018

Get rates
Opens in a new windowSomos Hotel Avenida
Roça Sundy – Principe Collection

Roça Sundy – Principe Collection

4 out of 5
Santo Antonio, Sundy Estate Príncipe Island
Book a stay at this business-friendly hotel in Príncipe Island. Enjoy free breakfast, free parking, and a free airport shuttle. Popular attractions Sundy Plantation ...
Get rates
Opens in a new windowRoça Sundy – Principe Collection
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Miramar São Tomé

Miramar São Tomé

3 out of 5
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $173 total per night from Nov 16 to Nov 17
$173 total
Nov 16 - Nov 17
Total with taxes and fees
Book a stay at this beach resort in São Tomé. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Estadio Nacional 12 de Julho and São ...
Opens in a new windowMiramar São Tomé
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

São Tomé and Príncipe

Save money on your flights to São Tomé and Príncipe as well as on hotel and car packages.

 

Free Fees

Snap up cheap São Tomé and Príncipe flights at Orbitz, and pay no booking fees. We also don’t charge fees when your plans change or are cancelled. While you’re there, check out our low fare deals on flights to other locations besides flights to São Tomé and Príncipe.

Everyday Is a Great Day to Save Even More

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Mix and Match

At Orbitz, we turned a great idea from the world of fashion into another way for you to save money. When you shop our low cost tickets on flights to any destination, don’t be afraid to mix and match different airlines for maximum savings on your São Tomé and Príncipe flights air ticket. Save more on air travel every day in every way at Orbitz.

Frequently asked questions

Which airlines fly to Sao Tome and Principe?
With 24 airlines ready to whisk you off to Sao Tome and Principe, finding a suitable flight will be a cinch. Lock in a ticket with one of these top carriers that offer services to Sao Tome Intl. Airport (TMS):

  • TAP Air Portugal - 4 flights to Sao Tome and Principe per month
  • TAAG Angola Airlines - 0 flights to Sao Tome and Principe per month
  • STP Airways - 0 flights to Sao Tome and Principe per month

What is the best airport to fly to in Sao Tome and Principe?
Jet into Sao Tome Intl. Airport (TMS), the main gateway to Sao Tome and Principe. Booking your flight to this region doesn't get much easier.
How much is a flight to Sao Tome and Principe?
This week, prices hovered between $453 and $2,331 for a return fare to Sao Tome and Principe. One-way fares from Lisbon (LIS) dropped as low as just $401 during the same time period.
How to book the cheapest flight to Sao Tome and Principe?
With some of the most exciting flight deals around, you'll always jet for less with Orbitz. The following useful tips will help you pick up cheap flights to Sao Tome and Principe — and leave you with more money to play with:

  • Departing from or arriving at other airports can sometimes help you save on airfares. Type in your preferred departure and arrival points. Next, click on the 'Nearby airports' function below the form fields to compare your options.
  • If your travel plans aren't set in concrete, click on the 'Show flexible dates' option to compare flight deals for a selection of departure dates. If you find a suitable cheaper fare, go with it.
  • You can also hit the 'Show options' link to filter results for your preferred carrier, seating class, nonstop flights and refundable flights. Under 'Sort & Filter' to the left, you can even choose the time of day you'd prefer to fly.
  • The early bird gets the best deals, so book as soon as you've worked out your travel dates. The most affordable fares go like hotcakes and prices rise as the departure date gets closer.
  • Bundle your hotels, flights and car rentals into a competitive package deal. Save your money for things you're really excited about, like exploring every corner of Sao Tome and Principe.
  • Flying during peak season means expensive airfares. Try to avoid traveling over popular dates, such as Thanksgiving, New Year's Eve and Easter.

What is the best time to book a flight to Sao Tome and Principe?
Generally speaking, January is the cheapest month to book your airfare. This is followed by February and August. Keep this in mind while you search for a cheap flight to Sao Tome and Principe.
What day of the week is the cheapest to book a flight to Sao Tome and Principe?
To find a fantastic flight deal, make a booking on a Tuesday, Wednesday or Saturday. These are generally the cheapest days of the week to purchase tickets to Sao Tome and Principe.
What is the cheapest day of the week to fly to Sao Tome and Principe?
According to Orbitz data from 2020, you ought to kick off your trip on a Monday to score cheap flights to Sao Tome and Principe. Next most inexpensive day? Tuesday. Saturday will cost the most. So, consider departing early in the week if you'd love to book a wallet-friendly fare and stretch your travel budget.
What is the cheapest month to fly to Sao Tome and Principe?
According to Orbitz data, it's better to fly out in August. This is generally a great month to land cheap flights to Sao Tome and Principe. Be aware that the most expensive time to fly is in June.
Which airlines allow free cancellation?
We understand that plans can change and flexibility matters. That's why you can search for flights that have free cancellation and no change fees on Orbitz. Just click on "Filter by flexible change policies" and we'll find you fares more flexible than candy in a car on a hot day!
What do I need for the flight to Sao Tome and Principe?
The trick to having a smooth and stress-free flight is to plan ahead. Here are a couple of tips to keep in mind before you depart:

  • Nothing is more important than your travel documents. Which to bring and how many depend on whether you're traveling international or domestic. Be sure to check with your airline. In both cases, you'll need to present photo identification.
  • Take a good book or a tablet filled with your favorite TV series — it'll help to pass time on your journey to Sao Tome and Principe. Or if you're hoping to take a snooze, an eye mask will shield you from those bright cabin lights.
  • Cabin temperatures can quickly change, so it's wise to bring an extra layer. Also consider compression socks. They can help prevent swelling and blood clots.

How many direct flights are there to Sao Tome and Principe?
With 6 flights traveling straight to Sao Tome and Principe every month, finding one to suit your itinerary will be a snap. STP Airways, TAP Portugal and TAAG are among the major carriers that provide nonstop services.
How do I get cheap first-class/business deals to Sao Tome and Principe?
If you think a business or first-class fare is beyond your reach, think again. Here are some terrific tips to help you pick up a premium flight to Sao Tome and Principe for a whole lot less:

  • Flexibility isn't just useful for your yoga. Have some room to move around your travel dates so you can snap up cheaper airfares when a sale pops up.
  • Search for a budget airline that has business-class seats. They often come with extra legroom and a glass of bubbly — and a nicer price.
  • Bid for an upgrade in online auctions or upgrade with loyalty points.

What is the best time to go to São Tomé and Príncipe?
There's no right or wrong time to visit São Tomé and Príncipe, but March, August and September are the liveliest months. As with most of the Northern Hemisphere, the summer season kicks off June 20. If you'd sooner spend your days in a light T-shirt than a heavy winter jacket, this time of year would be ideal for you. Expect average daily highs of 80 ºF and nightly lows around 75 ºF.
Travel tips for Sao Tome and Principe

  • Sao Tome and Principe has dozens of wonderful attractions and Market is one of them. Pick up a car rental and head there at your own speed.
  • Sao Tome Island offers tons of one-of-a-kind experiences and is a top place to kick off your vacation. Whether you're into art, cafés, restaurants or something else, this city will keep you entertained.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.