Compare Inns in Southeast Missouri

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Hotel Options in Southeast Missouri

    Drury Plaza Hotel Cape Girardeau Conference Center

    Drury Plaza Hotel Cape Girardeau Conference Center

    3351 Percy Drive Cape Girardeau MO
    $100 nightly
    The price is $113 total per night from Nov 15 to Nov 16
    $113 total
    Nov 15 - Nov 16
    Total with taxes and fees
    9.6/10 Exceptional! (1,007 reviews)
    Hampton Inn Poplar Bluff

    Hampton Inn Poplar Bluff

    2420 Crestwood Dr Poplar Bluff MO
    $90 nightly
    The price is $101 total per night from Nov 8 to Nov 9
    $101 total
    Nov 8 - Nov 9
    Total with taxes and fees
    9.4/10 Exceptional! (1,000 reviews)
    Drury Inn & Suites Sikeston, MO

    Drury Inn & Suites Sikeston, MO

    2608 East Malone Ave, Miner Sikeston MO
    $94 nightly
    The price is $108 total per night from Nov 1 to Nov 2
    $108 total
    Nov 1 - Nov 2
    Total with taxes and fees

Inns

Find a great Southeast Missouri inn
If you’re on the lookout for a place to stay in Southeast Missouri that sports special touches and décor but is less costly than a bed and breakfast, rent a room at an inn. Whether you’re staying for a day, a week or a month, Orbitz has a great selection of super-comfy Southeast Missouri inns to choose from.

Pick the right inn for you
The most popular hotel inns in Southeast Missouri merge the convenience of an inn with many of the standard features of a hotel. Think pools and gyms, without the hefty price tag.

You’ll find Southeast Missouri inns are located in all sort of convenient neighborhoods, making them a great option for those traveling on four wheels. They can also offer a tasty breakfast and hearty dinner, saving you the time and effort it would take to find good eats in a new place. 

If you want a space filled with loads of personality and a good helping of hospitality to boot, look out for historic inns. Privately owned with an exclusive number of rooms, you’ll receive a more personalized stay, much like a boutique hotel. No matter what type of inn you choose, you’re sure to enjoy unique experiences you won’t find anywhere else.

Southeast Missouri Inns essential information

Accommodation
Inns
Lowest Price
$101
Highest Price
$113
Popular accommodation
Drury Plaza Hotel Cape Girardeau Conference Center, Hampton Inn Poplar Bluff, Drury Inn & Suites Sikeston, MO

More to Explore