Hotels with Air Conditioning in Southeast Missouri
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Featured Southeast Missouri Hotels with Air Conditioning

Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$68 nightly
The price is $78 total per night
$78 total
Mar 29 - Mar 30
Total with taxes and fees
Renovated in 2023, Days Inn and Suites by Wyndham Sikeston offers a gym, free WiFi in public areas, and meeting rooms. Free parking is included with your stay. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a library, laundry facilities, and a vending machine.
Breakfast included
Pet friendly

Super 8 by Wyndham Pevely
1711 Highway Z Pevely MO
Free Cancellation
Reserve now, pay when you stay
$79 nightly
The price is $91 total per night
$91 total
Mar 29 - Mar 30
Total with taxes and fees
At Super 8 by Wyndham Pevely, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. The 24-hour front desk has staff always at the ready. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Pool
Breakfast included

Best Western Plus Sikeston I-55
120 S Interstate Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$93 nightly
The price is $106 total per night
$106 total
Apr 2 - Apr 3
Total with taxes and fees
Guests of Best Western Plus Sikeston I-55 have access to an indoor pool, a gym, and free WiFi in public areas. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a 24-hour business center, a computer station, and express check-out.
Pool
Breakfast included

Candlewood Suites Cape Girardeau by IHG
485 S Mount Auburn Rd Cape Girardeau MO
Free Cancellation
$80 nightly
The price is $96 total per night
$96 total
Apr 2 - Apr 3
Total with taxes and fees
At Candlewood Suites Cape Girardeau by IHG, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include meeting rooms, a business center, and free newspapers.
Pool
Pet friendly

Comfort Inn Festus - St Louis South
1303 Veterans Blvd Festus MO
Free Cancellation
$73 nightly
The price is $83 total per night
$83 total
Apr 19 - Apr 20
Total with taxes and fees
At Comfort Inn Festus - St Louis South, guests have access to a gym, free WiFi in public areas, and a business center. Free parking is included with your stay. Front-desk staff can answer questions 24/7, and assist with tours or tickets, dry cleaning/laundry, and securing valuables. Additional amenities include free newspapers, laundry facilities, and a gift shop.
Breakfast included
Parking included

Quality Inn Perryville I-55
1517 S. Perryville Blvd. Perryville MO
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $92 total per night
$92 total
Mar 29 - Mar 30
Total with taxes and fees
Guests of Quality Inn Perryville I-55 have access to an outdoor pool, a gym, and a hot tub. You can put free parking to good use if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a seasonal outdoor pool, coffee/tea in a common area, and a meeting room.

Comfort Suites Jackson-Cape Girardeau
2904 Old Orchard Rd Jackson MO
Free Cancellation
$92 nightly
The price is $100 total per night
$100 total
Mar 29 - Mar 30
Total with taxes and fees
At Comfort Suites Jackson-Cape Girardeau, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include conference space, a 24-hour business center, and a computer station.
Pool
Breakfast included

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
100 Matthews Lane Sikeston MO
Free Cancellation
Reserve now, pay when you stay
$65 nightly
The price is $75 total per night
$75 total
Mar 29 - Mar 30
Total with taxes and fees
Guests of Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) enjoy free WiFi in public areas, coffee in a common area, and a vending machine. If you drive, take advantage of free parking. The 24-hour front desk has staff always at the ready.
Breakfast included
Pet friendly

Crown Pointe Lodge, BW Signature Collection
4245 Hunt Rd Farmington MO
Free Cancellation
Reserve now, pay when you stay
$110 nightly
The price is $125 total per night
$125 total
Apr 5 - Apr 6
Total with taxes and fees
Crown Pointe Lodge, BW Signature Collection features a golf course, an indoor pool, and a gym. There's free parking and an area shuttle. The 24-hour front desk has staff always at the ready. Other amenities at this golf hotel include free WiFi in public areas, a hot tub, and a business center.
Pool
Hot Tub

Econo Lodge Kennett
110 Independence Ave Kennett MO
Free Cancellation
Reserve now, pay when you stay
$60 nightly
The price is $69 total per night
$69 total
Mar 27 - Mar 28
Total with taxes and fees
Econo Lodge Kennett features free WiFi in public areas, a seasonal outdoor pool, and coffee in a common area. If you drive, put free parking to good use. The 24-hour front desk has staff always at the ready. Other amenities at this golf hotel include free newspapers, laundry facilities, and a vending machine.
Pool
Breakfast included

Days Inn by Wyndham Perryville
1500 Liberty Street Perryville MO
Free Cancellation
Reserve now, pay when you stay
$71 nightly
The price is $82 total per night
$82 total
Mar 29 - Mar 30
Total with taxes and fees
Guests of Days Inn by Wyndham Perryville enjoy access to free WiFi in public areas, a business center, and a seasonal outdoor pool. You can put free parking to good use if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include coffee/tea in a common area, free newspapers, and laundry facilities.
Pool
Breakfast included

Dexter Inn
1807 W Business US Highway 60 Dexter MO
Free Cancellation
Reserve now, pay when you stay
$54 nightly
The price is $61 total per night
$61 total
Apr 1 - Apr 2
Total with taxes and fees
Guests of Dexter Inn enjoy access to free WiFi in public areas, meeting rooms, and a seasonal outdoor pool. If you decide to drive, there's free parking. The 24-hour front desk has staff always at the ready. Additional amenities include coffee/tea in a common area, laundry facilities, and a banquet hall.

Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
Free Cancellation
Reserve now, pay when you stay
$90 nightly
The price is $102 total per night
$102 total
Apr 2 - Apr 3
Total with taxes and fees
Guests of Drury Inn & Suites Cape Girardeau have access to an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a hot tub, meeting rooms, and a business center.

Drury Inn & Suites Hayti Caruthersville
1317 E Highway 84 Hayti MO
Free Cancellation
Reserve now, pay when you stay
$94 nightly
The price is $107 total per night
$107 total
Apr 5 - Apr 6
Total with taxes and fees
At Drury Inn & Suites Hayti Caruthersville, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, put free parking to good use. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. Additional amenities include a hot tub, meeting rooms, and a business center.
Pool
Hot Tub

Drury Inn & Suites Jackson MO
225 Drury Lane Jackson MO
Free Cancellation
Reserve now, pay when you stay
$80 nightly
The price is $85 total per night
$85 total
Apr 8 - Apr 9
Total with taxes and fees
Guests of Drury Inn & Suites Jackson MO have access to an indoor pool, a gym, and free WiFi in public areas. There's free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a hot tub, meeting rooms, and a business center.
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See all available properties in Southeast Missouri
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Southeast Missouri hotels essential information
Accommodation | 630 hotels |
|---|---|
Lowest Price | $61 |
Highest Price | $125 |
Popular hotels | Days Inn and Suites by Wyndham Sikeston, Super 8 by Wyndham Pevely, Best Western Plus Sikeston I-55, Candlewood Suites Cape Girardeau by IHG, Comfort Inn Festus - St Louis South, Quality Inn Perryville I-55, Comfort Suites Jackson-Cape Girardeau, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67), Crown Pointe Lodge, BW Signature Collection, Econo Lodge Kennett, Days Inn by Wyndham Perryville, Dexter Inn, Drury Inn & Suites Cape Girardeau, Drury Inn & Suites Hayti Caruthersville, Drury Inn & Suites Jackson MO |
Recent Hotels with Air Conditioning Reviews

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
5/5 Excellent
"We pre-checked, which was great, and the staff that helped us get our keys was so great! Our room was spacious, quiet, clean, and comfortable. The pool was a little cool, but still refreshing. The shower was hot and the shower head was high enough up for our tall family. The breakfast was pretty average for a hotel, with eggs, sausage, waffles, cereal, yougurt, juice, milk, and coffee. Checking out was a cinch too. Overall 9.8/10 would definitely stop again!"
A verified traveler stayed at La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Posted 20 hours ago
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