LGBTQ Welcoming Hotels in South Main, Houston
Our top South Main LGBTQ hotel partners

Wyndham Houston at Reliant Park & Medical Center
8686 Kirby Drive Houston TX
Free Cancellation
Reserve now, pay when you stay
$99 nightly
The price is $116 total per night
$116 total
Nov 15 - Nov 16
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, a 24-hour fitness center, and onsite spa services. Our guests praise the helpful staff ...

Candlewood Suites Houston Medical Center by IHG
10025 S Main Street Houston TX
Free Cancellation
$78 nightly
The price is $91 total per night
$91 total
Nov 17 - Nov 18
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, free parking, and a 24-hour fitness center. Popular attractions Reliant Stadium and ...

Wingate Houston near Reliant Park/Medical Center
8600 Kirby Drive Houston TX
Free Cancellation
Reserve now, pay when you stay
$89 nightly
The price is $104 total per night
$104 total
Nov 16 - Nov 17
Total with taxes and fees
Book a stay at this business-friendly hotel in Houston. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the clean rooms in our reviews. ...
LGBTQIA welcoming hotels in top travel spots

Las Vegas LGBTQIA hotels

Miami LGBTQIA hotels

New Orleans LGBTQIA hotels

New York LGBTQIA hotels

Palm Springs LGBTQIA hotels

Puerto Vallarta LGBTQIA hotels
South Main hotels essential information
Accommodation | hotels |
|---|---|
Lowest Price | $91 |
Highest Price | $116 |
Popular hotels | Wyndham Houston at Reliant Park & Medical Center, Candlewood Suites Houston Medical Center by IHG, Wingate Houston near Reliant Park/Medical Center |



