Santiago Vacation Homes

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Featured Vacation Homes in Santiago

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Santiago

    Barceló Praia Cape Verde

    Barceló Praia Cape Verde

    Av. Rotary International Praia Praia
    $180 nightly
    The price is $212 total per night from Jan 4 to Jan 5
    $212 total
    Jan 4 - Jan 5, 2026
    Total with taxes and fees
    9.2/10 Wonderful! (90 reviews)
    Pestana Trópico - Ocean & City Hotel

    Pestana Trópico - Ocean & City Hotel

    Prainha, Cidade Da Praia Praia Santiago
    $168 nightly
    The price is $199 total per night from Dec 21 to Dec 22
    $199 total
    Dec 21 - Dec 22
    Total with taxes and fees
    8.4/10 Very Good! (257 reviews)
    Hotel Pérola

    Hotel Pérola

    Chã de Areia Praia
    8.6/10 Excellent! (175 reviews)

Santiago Vacation Homes

Book vacation homes in Santiago
Next time you take a group getaway top Santiago, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Santiago vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Santiago vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Santiago; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Santiago rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Santiago is sure to be a winner.

Santiago Vacation Homes essential information

Accommodation
32 Vacation Homes
Lowest Price
$75
Highest Price
$212
Popular accommodation
Apartment, 3 floor with sea views, Spacious Penthouse w/ Barbecue, wifi, 2 terraces & Views, City Center Luxurious Suite (Techa’s Place), 4 Bedroom Private vacation home in Vila do Maio, Cubico Tota, Villa Santa Cruz Santiago, Pousada Residencia Águia, Family spacious house, Property just updated with fresh paint, new flooring , new and modern furniture.