Business Hotels in Opelousas, LA
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Featured Opelousas Business Hotels
Holiday Inn Express & Suites Opelousas by IHG
5696 I-49 N Service Rd Opelousas LA
Free Cancellation
$100 nightly
The price is $118 total per night
$118 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
Guests of Holiday Inn Express & Suites Opelousas by IHG have access to an indoor pool, a 24-hour gym, and free WiFi in public areas. If you decide to drive, there's free parking. The front desk is staffed 24/7 to help with securing valuables, dry cleaning/laundry, and luggage storage. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pool
Breakfast included
Spark by Hilton Opelousas
5454 I-49 North Service Rd. Opelousas LA
Free Cancellation
Reserve now, pay when you stay
$75 nightly
The price is $88 total per night
$88 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Renovated in 2025, Spark by Hilton Opelousas offers free WiFi in public areas, coffee in a common area, and express check-out. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with dry cleaning/laundry and securing valuables. Additional amenities include free newspapers, laundry facilities, and a vending machine.
Pool
Breakfast included
Days Inn & Suites by Wyndham Opelousas
5761 I-49 S Service Rd Opelousas LA
Free Cancellation
Reserve now, pay when you stay
$68 nightly
The price is $79 total per night
$79 total
Jan 18 - Jan 19, 2026
Total with taxes and fees
Days Inn & Suites by Wyndham Opelousas features an outdoor pool, free WiFi in public areas, and conference space. You can take advantage of free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include laundry facilities, a banquet hall, and a vending machine.
Pool
Breakfast included
Evangeline Downs Hotel, an Ascend Collection Hotel
2235 Creswell Ln Ext, Lot B Opelousas LA
Free Cancellation
$112 nightly
The price is $132 total per night
$132 total
Jan 25 - Jan 26, 2026
Total with taxes and fees
Guests of Evangeline Downs Hotel, an Ascend Collection Hotel enjoy a casino, a nightclub, and an indoor pool. You can put free parking to good use if you drive. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations. Additional amenities include a gym, free WiFi in public areas, and a conference center.
Pool
Breakfast included
Studio 6 Opelousas, LA
5791 I-49 S Service Road Opelousas LA
Free Cancellation
Reserve now, pay when you stay
$65 nightly
The price is $77 total per night
$77 total
Dec 28 - Dec 29
Total with taxes and fees
At Studio 6 Opelousas, LA, guests have access to a vending machine. Free parking is included with your stay. The 24-hour front desk has staff always at the ready.
Pet friendly
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Opelousas hotels essential information
Accommodation | 438 hotels |
|---|---|
Lowest Price | $77 |
Highest Price | $132 |
Popular hotels | Holiday Inn Express & Suites Opelousas by IHG, Spark by Hilton Opelousas, Days Inn & Suites by Wyndham Opelousas, Evangeline Downs Hotel, an Ascend Collection Hotel, Studio 6 Opelousas, LA |
Recent Business Hotels Reviews
Evangeline Downs Hotel, an Ascend Collection Hotel
5/5 Excellent
"Courteous staff at front desk & cleanious"
A verified traveler stayed at Evangeline Downs Hotel, an Ascend Collection Hotel
Posted 1 day ago
