Hotels in Mission Hill
Search over 109 hotels from $66
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Top Rated Mission Hill Hotels

Best Western Vermillion Inn
701 W Cherry St Vermillion SD
Free Cancellation
Reserve now, pay when you stay
19.46 mi from city center
$96 nightly
The price is $106 total per night
$106 total
Jan 13 - Jan 14, 2026
Total with taxes and fees
At Best Western Vermillion Inn, guests enjoy features like an indoor pool, a gym, and a sauna. If you drive, put free parking to good use. Front-desk staff can answer questions 24/7, and assist with luggage storage, concierge services, and securing valuables. Additional amenities include free WiFi in public areas, a hot tub, and a 24-hour business center.
Pool
Hot Tub

Comfort Inn Yankton SD
611 W 23rd Street Yankton SD
Free Cancellation
Reserve now, pay when you stay
6.55 mi from city center
$88 nightly
The price is $98 total per night
$98 total
Dec 30 - Dec 31
Total with taxes and fees
At Comfort Inn Yankton SD, guests have access to a gym, free WiFi in public areas, and a hot tub. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a business center, coffee/tea in a common area, and express check-in.
Hot Tub
Breakfast included

Holiday Inn Express Hotel & Suites Vermillion by IHG
1200 N Dakota St Vermillion SD
19.83 mi from city center
$113 nightly
The price is $125 total per night
$125 total
Dec 28 - Dec 29
Total with taxes and fees
At Holiday Inn Express Hotel & Suites Vermillion by IHG, guests enjoy features like an indoor pool, a 24-hour gym, and free WiFi in public areas. If you plan to drive, free parking is available. The 24-hour front desk has staff standing by to help with securing valuables and luggage storage. Additional amenities include a 24-hour business center, a meeting room, and a computer station.
Pool
Parking included

Best Western Kelly Inn
1607 E Highway 50 Yankton SD
Free Cancellation
Reserve now, pay when you stay
5.37 mi from city center
$98 nightly
The price is $109 total per night
$109 total
Dec 30 - Dec 31
Total with taxes and fees
Best Western Kelly Inn features an indoor pool, a children's pool, and a gym. If you drive, put free parking to good use. Front-desk staff can answer questions 24/7, and assist with securing valuables, luggage storage, and dry cleaning/laundry. Additional amenities include free WiFi in public areas, a hot tub, and meeting rooms.
Pool
Hot Tub

Fairfield Inn & Suites by Marriott Yankton
508 WEST 21ST STREET Yankton SD
Free Cancellation
Reserve now, pay when you stay
6.42 mi from city center
$119 nightly
The price is $131 total per night
$131 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
Guests staying at Fairfield Inn & Suites by Marriott Yankton enjoy an indoor pool, free WiFi in public areas, and a banquet hall. If you plan to drive, free parking is available. The front desk is staffed 24/7 to help secure valuables, and answer any questions about the accommodations.
Pool
Breakfast included

Econo Lodge Inn & Suites
2410 Broadway Ave Yankton SD
Free Cancellation
Reserve now, pay when you stay
6.21 mi from city center
$77 nightly
The price is $85 total per night
$85 total
Dec 30 - Dec 31
Total with taxes and fees
At Econo Lodge Inn & Suites Yankton, guests have access to an indoor pool, free WiFi in public areas, and a hot tub. If you drive, take advantage of free parking. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include conference space, a business center, and coffee/tea in a common area.
Pool
Hot Tub

Holiday Inn Express & Suites Yankton by IHG
2607 Broadway Ave Yankton SD
Free Cancellation
6.23 mi from city center
$106 nightly
The price is $117 total per night
$117 total
Jan 21 - Jan 22, 2026
Total with taxes and fees
At Holiday Inn Express & Suites Yankton by IHG, guests enjoy an indoor pool, a gym, and free WiFi in public areas. If you drive, take advantage of free parking. The front desk is staffed 24 hours a day to help with securing valuables and dry cleaning/laundry. Additional amenities include a hot tub, a business center, and a meeting room.
Pool
Hot Tub

Red Roof Inn Vermillion - U of South Dakota
1208 E Cherry St Vermillion SD
Free Cancellation
Reserve now, pay when you stay
20.77 mi from city center
$79 nightly
The price is $88 total per night
$88 total
Dec 25 - Dec 26
Total with taxes and fees
Red Roof Inn Vermillion - U of South Dakota features an indoor pool, free WiFi in public areas, and coffee in a common area. A stay here includes free parking. The 24-hour front desk has staff always at the ready. This smoke-free hotel also has a vending machine.
Pool
Pet friendly

Yankton Inn
1603 East Highway 50 Yankton SD
Free Cancellation
Reserve now, pay when you stay
5.46 mi from city center
$80 nightly
The price is $90 total per night
$90 total
Dec 29 - Dec 30
Total with taxes and fees
Yankton Inn offers free WiFi in public areas and coffee in a common area. Free parking is available if you drive. Front-desk staff are standing by 24/7 to assist with any requests.
Breakfast included
Pet friendly

Lewis and Clark Resort
43496 Shore Drive Yankton SD
12.87 mi from city center
$94 nightly
The price is $99 total per night
$99 total
Dec 28 - Dec 29
Total with taxes and fees
Guests of Lewis and Clark Resort enjoy features like a marina, free WiFi in public areas, and a conference center. If you drive, put free parking to good use. Front-desk staff can help with luggage storage, and provide local restaurant recommendations. Other amenities at this beach hotel include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Pet friendly

Cobblestone Inn & Suites - Hartington
405 Arens Dr Hartington NE
21.13 mi from city center
$120 nightly
The price is $139 total per night
$139 total
Dec 27 - Dec 28
Total with taxes and fees
Guests of Cobblestone Inn & Suites - Hartington enjoy a gym, free WiFi in public areas, and a conference center. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to help secure valuables, and answer any questions about the area. Additional amenities include a business center, a computer station, and express check-in.
Breakfast included
Pet friendly

Prairie Inn
916 N Dakota Street Vermillion SD
19.9 mi from city center
$60 nightly
The price is $66 total per night
$66 total
Dec 27 - Dec 28
Total with taxes and fees
At Prairie Inn, guests have access to free WiFi in public areas, free newspapers, and laundry facilities. If you plan to drive, free parking is available. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include a vending machine and an ATM.
Pet friendly
Parking included
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
What's the best place for a stay in Mission Hill?
What are some favorite hotels in Mission Hill?
Consider these top hotels around Mission Hill:
- Best Western Vermillion Inn is located 19.5 mi away, and this hotel has free breakfast, free parking, and a fitness center.
- Comfort Inn Yankton SD is located 6.6 mi away, and this hotel has free breakfast, free WiFi, and free parking.
- Fairfield Inn & Suites by Marriott Yankton is located 6.4 mi away, and this hotel has free breakfast, free parking, and Smart TVs.
Mission Hill hotels essential information
Accommodation | 109 hotels |
|---|---|
Lowest Price | $66 |
Highest Price | $139 |
Popular hotels | Best Western Vermillion Inn, Comfort Inn Yankton SD, Holiday Inn Express Hotel & Suites Vermillion by IHG, Best Western Kelly Inn, Fairfield Inn & Suites by Marriott Yankton, Econo Lodge Inn & Suites, Holiday Inn Express & Suites Yankton by IHG, Red Roof Inn Vermillion - U of South Dakota, Yankton Inn, Lewis and Clark Resort, Cobblestone Inn & Suites - Hartington, Prairie Inn |
Recent Reviews

Comfort Inn Yankton SD
5/5 Excellent
"Very clean room. Odor free."
A verified traveler stayed at Comfort Inn Yankton SD
Posted 4 days ago
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