Mayo Vacation Homes

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Featured Vacation Homes in Mayo

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Mayo

    Suwannee River Rendezvous

    Suwannee River Rendezvous

    828 NE Primrose Rd, Mayo, FL
    The price is $117 per night from May 3 to May 4
    $117
    includes taxes & fees
    $109 per night
    May 3 - May 4
    8.2/10 Very Good! (12 reviews)
    Cindys Motel

    Cindys Motel

    487 W Main St, Mayo, FL
    The price is $105 per night from May 18 to May 19
    $105
    includes taxes & fees
    $98 per night
    May 18 - May 19
    8.8/10 Excellent! (107 reviews)
    Best Western Plus Madison

    Best Western Plus Madison

    167 SE Bandit Street, Madison, FL
    The price is $147 per night from May 8 to May 9
    $147
    includes taxes & fees
    $131 per night
    May 8 - May 9
    8/10 Very Good! (529 reviews)

Mayo Vacation Homes

Book vacation homes in Mayo
Next time you take a group getaway top Mayo, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Mayo vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Mayo vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Mayo; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Mayo rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Mayo is sure to be a winner.

Mayo Vacation Homes essential information

Accommodation
190 Vacation Homes
Lowest Price
$105
Highest Price
$312
Popular accommodation
Right on the River: Enjoy the Santa Fe + Ichetucknee Rivers from a Private Dock, Steinhatchee Home w/ Boat Parking: 1 Mi to Marina, Scallop and Fishing Paradise, 3-bedroom Riverfront home with private boat dock and view of Steinhatchee River., Dekle Beach Darling - Beautiful Sunsets and Great Fishing , The Coppertop Inn on The Ichetucknee River Pets are Welcome 50 per pet fee, ICHETUCKNEE RIVER - Riverfront on the Crystal Clear Ichetucknee River, Pet-Friendly Florida Escape w/ Patio & Fire Pit!, Resort perks, cottage privacy, boat slip access