$346 Cheap flights to São Tomé and Príncipe

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Cheap flights to São Tomé and Príncipe from $346 One Way, $452 Round Trip

$452 return flights and $346 one-way flights to São Tomé and Príncipe were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Sep 23 - Wed, Sep 30
ACC
Accra
TMS
São Tomé Island
$452 Roundtrip, found 2 days ago
$452
Roundtrip
found 2 days ago
Select TAP Portugal flight, departing Wed, Sep 23 from Accra to São Tomé Island, returning Wed, Sep 30, priced at $452 found 2 days ago
Sat, Jan 30 - Wed, Feb 3
LIS
Lisbon
TMS
São Tomé Island
$584 Roundtrip, found 4 days ago
$584
Roundtrip
found 4 days ago
Select TAAG Angola Airlines flight, departing Sat, Jan 30 from Lisbon to São Tomé Island, returning Wed, Feb 3, priced at $584 found 4 days ago
Sat, Oct 3 - Sun, Oct 18
LIS
Lisbon
TMS
São Tomé Island
$584 Roundtrip, found 6 days ago
$584
Roundtrip
found 6 days ago
Select TAAG Angola Airlines flight, departing Sat, Oct 3 from Lisbon to São Tomé Island, returning Sun, Oct 18, priced at $584 found 6 days ago
Sun, Dec 20 - Sun, Dec 27
ACC
Accra
TMS
São Tomé Island
$588 Roundtrip, found 4 days ago
$588
Roundtrip
found 4 days ago
Select TAP Portugal flight, departing Sun, Dec 20 from Accra to São Tomé Island, returning Sun, Dec 27, priced at $588 found 4 days ago
Thu, Jul 23 - Fri, Jul 31
ACC
Accra
TMS
São Tomé Island
$754 Roundtrip, found 2 days ago
$754
Roundtrip
found 2 days ago
Select ASKY flight, departing Thu, Jul 23 from Accra to São Tomé Island, returning Fri, Jul 31, priced at $754 found 2 days ago
Sat, Jan 2 - Sat, Jan 23
CPH
Copenhagen
TMS
São Tomé Island
$1,355 Roundtrip, found 8 hours ago
$1,355
Roundtrip
found 8 hours ago
Select TAP Portugal flight, departing Sat, Jan 2 from Copenhagen to São Tomé Island, returning Sat, Jan 23, priced at $1,355 found 8 hours ago
Sat, Nov 21 - Sat, Nov 28
EWR
New York
TMS
São Tomé Island
$1,779 Roundtrip, found 3 days ago
$1,779
Roundtrip
found 3 days ago
Select Brussels Airlines flight, departing Sat, Nov 21 from New York to São Tomé Island, returning Sat, Nov 28, priced at $1,779 found 3 days ago
Wed, Jan 13 - Sat, Jan 23
TPA
Tampa
TMS
São Tomé Island
$1,780 Roundtrip, found 2 days ago
$1,780
Roundtrip
found 2 days ago
Select Air Canada flight, departing Wed, Jan 13 from Tampa to São Tomé Island, returning Sat, Jan 23, priced at $1,780 found 2 days ago
Wed, Jan 13 - Sat, Jan 23
TPA
Tampa
TMS
São Tomé Island
$1,801 Roundtrip, found 2 days ago
$1,801
Roundtrip
found 2 days ago
Select Air Canada flight, departing Wed, Jan 13 from Tampa to São Tomé Island, returning Sat, Jan 23, priced at $1,801 found 2 days ago
Wed, Jan 13 - Sat, Jan 23
TPA
Tampa
TMS
São Tomé Island
$1,872 Roundtrip, found 2 days ago
$1,872
Roundtrip
found 2 days ago
Select Air Canada flight, departing Wed, Jan 13 from Tampa to São Tomé Island, returning Sat, Jan 23, priced at $1,872 found 2 days ago
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Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
LISSão ToméMay 9 to May 23$1,162
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Our Top São Tomé and Príncipe Apartment Hotels

Sweet Guest House

Sweet Guest House

2.5 out of 5
Vila Dolores n. 087 São Tomé
Book a stay at this spa guesthouse in São Tomé. Enjoy free WiFi, free parking, and a full-service spa. Popular attractions Cloçon Téla Chocolate Factory and ...
Get rates
Opens in a new windowSweet Guest House
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic São Tomé and Príncipe Accommodation Deals

Pestana São Tomé

Pestana São Tomé

5 out of 5
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
$232 nightly
The price is $267 total per night from May 7 to May 8
$267 total
May 7 - May 8
Total with taxes and fees
Book a stay at this luxury hotel in São Tomé. Enjoy free WiFi, free parking, and a beach locale. Popular attractions Estadio Nacional 12 de Julho and Cloçon ...
Opens in a new windowPestana São Tomé
Pestana Miramar São Tomé

Pestana Miramar São Tomé

3 out of 5
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $195 total per night from May 7 to May 8
$195 total
May 7 - May 8
Total with taxes and fees
Book a stay at this beach resort in São Tomé. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Estadio Nacional 12 de Julho and São ...
Opens in a new windowPestana Miramar São Tomé
Omali São Tomé – Principe Collection

Omali São Tomé – Principe Collection

4 out of 5
Praia Lagarto São Tomé
$224 nightly
The price is $262 total per night from May 20 to May 21
$262 total
May 20 - May 21
Total with taxes and fees
Book a stay at this beach resort in São Tomé. Enjoy free breakfast, free WiFi, and free parking. Popular attractions São Sebastião Museum and Cloçon Téla Chocolate ...
9.4/10 Exceptional! (63 reviews)
Lovely hotel, staff and location. Very close to airport as well Recommend highly

Reviewed on Mar 8, 2026

Opens in a new windowOmali São Tomé – Principe Collection
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Hotel Central

Hotel Central

3.5 out of 5
Rua de Angola São Tomé São Tomé
$56 nightly
The price is $65 total per night from May 13 to May 14
$65 total
May 13 - May 14
Total with taxes and fees
Book a stay at this business-friendly hotel in São Tomé. Enjoy free breakfast, free parking, and an airport shuttle (surcharge). Popular attractions Cloçon Téla ...
Opens in a new windowHotel Central
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in São Tomé and Príncipe

Bom Bom – Principe Collection

Bom Bom – Principe Collection

4 out of 5
Bom Bom Island Príncipe Island
$529 nightly
The price is $612 total per night from May 29 to May 30
$612 total
May 29 - May 30
Total with taxes and fees
Book a stay at this beach hotel in Príncipe Island. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Margarida Beach and Sundy Plantation ...
8.4/10 Very Good! (7 reviews)
Outstanding hotel and location, but much too expensive, especially for Sao Tome

Reviewed on Jan 8, 2026

Opens in a new windowBom Bom – Principe Collection
Somos Hotel Avenida

Somos Hotel Avenida

3 out of 5
Avenida da Independencia São Tomé São Tomé
Book a stay at this business-friendly hotel in São Tomé. Enjoy free breakfast, free parking, and room service. Popular attractions Estadio Nacional 12 de Julho ...
6.6/10 (4 reviews)
Good
Good

Reviewed on Aug 29, 2018

Get rates
Opens in a new windowSomos Hotel Avenida
Roça Sundy – Principe Collection

Roça Sundy – Principe Collection

4 out of 5
Santo Antonio, Sundy Estate Príncipe Island
Book a stay at this business-friendly hotel in Príncipe Island. Enjoy free breakfast, free parking, and a free airport shuttle. Popular attractions Sundy Plantation ...
Get rates
Opens in a new windowRoça Sundy – Principe Collection
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Pestana Miramar São Tomé

Pestana Miramar São Tomé

3 out of 5
Avenida Marginal 12 De Julho São Tomé
Fully refundableReserve now, pay when you stay
$169 nightly
The price is $195 total per night from May 7 to May 8
$195 total
May 7 - May 8
Total with taxes and fees
Book a stay at this beach resort in São Tomé. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Estadio Nacional 12 de Julho and São ...
Opens in a new windowPestana Miramar São Tomé
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

São Tomé and Príncipe

Traveling to São Tomé and Príncipe and need a cheap flight? Orbitz has great deals on flights to São Tomé and Príncipe right now. Plus, we offer big discounts on hotel rooms and car rentals for a great money-saving trip.

Find Low Cost Flights to São Tomé and Príncipe Quickly and Hassle-Free

There are many Internet sites that promise cheap São Tomé and Príncipe flights, but a busy, bargain-minded trip planner needs more than just budget air tickets. Not only does Orbitz offer the best deals for domestic and international air fare, but we also provide the resources and tools to help you plan your flights to São Tomé and Príncipe, book your lodging, and look up key attractions in São Tomé and Príncipe. Our easy search tools and guaranteed low prices let you budget your time and your money so you have more of both to spend on your vacation.

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You no longer need to be sitting at your computer to find amazing Orbitz sales for flights to São Tomé and Príncipe now we offer cutting-edge mobile tools for many Android and iOS gadgets. These free apps allow you to run a search for discount air fare, look for special vacation packages, or check on your booked São Tomé and Príncipe flights from any location. Some special deals are only available for mobile customers, so be sure to take advantage of these free downloads today.

Orbitz Customers Are Truly #1

Orbitz takes pride in providing the best customer experience possible, and that effort doesn't end with discount flights to São Tomé and Príncipe or user-friendly mobile apps and web tools. Orbitz Customer Service is always ready to answer questions and help you with booking, planning, or canceling your São Tomé and Príncipe flights. When you need us, we’re here for you!

Frequently asked questions

Which airlines fly to Sao Tome and Principe?
With 20 airlines ready to whisk you off to Sao Tome and Principe, finding a suitable flight will be a cinch. Lock in a ticket with one of these top carriers that offer services to Sao Tome Intl. Airport (TMS):

  • TAP Air Portugal - 4 flights to Sao Tome and Principe per month
  • TAAG Angola Airlines - 0 flights to Sao Tome and Principe per month
  • STP Airways - 0 flights to Sao Tome and Principe per month

What is the best airport to fly to in Sao Tome and Principe?
Jet into Sao Tome Intl. Airport (TMS), the main gateway to Sao Tome and Principe. Booking your flight to this region doesn't get much easier.
How much is a flight to Sao Tome and Principe?
This week, prices hovered between $452 and $1,872 for a return fare to Sao Tome and Principe. One-way fares from Lisbon (LIS) dropped as low as just $346 during the same time period.
How to book the cheapest flight to Sao Tome and Principe?
With some of the most exciting flight deals around, you'll always jet for less with Orbitz. The following useful tips will help you pick up cheap flights to Sao Tome and Principe — and leave you with more money to play with:

  • Departing from or arriving at other airports can sometimes help you save on airfares. Type in your preferred departure and arrival points. Next, click on the 'Nearby airports' function below the form fields to compare your options.
  • If your travel plans aren't set in concrete, click on the 'Show flexible dates' option to compare flight deals for a selection of departure dates. If you find a suitable cheaper fare, go with it.
  • You can also hit the 'Show options' link to filter results for your preferred carrier, seating class, nonstop flights and refundable flights. Under 'Sort & Filter' to the left, you can even choose the time of day you'd prefer to fly.
  • The early bird gets the best deals, so book as soon as you've worked out your travel dates. The most affordable fares go like hotcakes and prices rise as the departure date gets closer.
  • Bundle your hotels, flights and car rentals into a competitive package deal. Save your money for things you're really excited about, like exploring every corner of Sao Tome and Principe.
  • Flying during peak season means expensive airfares. Try to avoid traveling over popular dates, such as Thanksgiving, New Year's Eve and Easter.

What is the best time to book a flight to Sao Tome and Principe?
Generally speaking, January is the cheapest month to book your airfare. This is followed by February and August. Keep this in mind while you search for a cheap flight to Sao Tome and Principe.
What day of the week is the cheapest to book a flight to Sao Tome and Principe?
To find a fantastic flight deal, make a booking on a Tuesday, Wednesday or Saturday. These are generally the cheapest days of the week to purchase tickets to Sao Tome and Principe.
What is the cheapest day of the week to fly to Sao Tome and Principe?
According to Orbitz data from 2020, you ought to kick off your trip on a Monday to score cheap flights to Sao Tome and Principe. Next most inexpensive day? Tuesday. Saturday will cost the most. So, consider departing early in the week if you'd love to book a wallet-friendly fare and stretch your travel budget.
What is the cheapest month to fly to Sao Tome and Principe?
According to Orbitz data, it's better to fly out in August. This is generally a great month to land cheap flights to Sao Tome and Principe. Be aware that the most expensive time to fly is in June.
Which airlines allow free cancellation?
We understand that plans can change and flexibility matters. That's why you can search for flights that have free cancellation and no change fees on Orbitz. Just click on "Filter by flexible change policies" and we'll find you fares more flexible than candy in a car on a hot day!
What do I need for the flight to Sao Tome and Principe?
The trick to having a smooth and stress-free flight is to plan ahead. Here are a couple of tips to keep in mind before you depart:

  • Nothing is more important than your travel documents. Which to bring and how many depend on whether you're traveling international or domestic. Be sure to check with your airline. In both cases, you'll need to present photo identification.
  • Take a good book or a tablet filled with your favorite TV series — it'll help to pass time on your journey to Sao Tome and Principe. Or if you're hoping to take a snooze, an eye mask will shield you from those bright cabin lights.
  • Cabin temperatures can quickly change, so it's wise to bring an extra layer. Also consider compression socks. They can help prevent swelling and blood clots.

How many direct flights are there to Sao Tome and Principe?
With 6 flights traveling straight to Sao Tome and Principe every month, finding one to suit your itinerary will be a snap. STP Airways, TAP Portugal and TAAG are among the major carriers that provide nonstop services.
How do I get cheap first-class/business deals to Sao Tome and Principe?
If you think a business or first-class fare is beyond your reach, think again. Here are some terrific tips to help you pick up a premium flight to Sao Tome and Principe for a whole lot less:

  • Flexibility isn't just useful for your yoga. Have some room to move around your travel dates so you can snap up cheaper airfares when a sale pops up.
  • Search for a budget airline that has business-class seats. They often come with extra legroom and a glass of bubbly — and a nicer price.
  • Bid for an upgrade in online auctions or upgrade with loyalty points.

What is the best time to go to São Tomé and Príncipe?
There's no right or wrong time to visit São Tomé and Príncipe, but March, August and September are the liveliest months. As with most of the Northern Hemisphere, the summer season kicks off June 20. If you'd sooner spend your days in a light T-shirt than a heavy winter jacket, this time of year would be ideal for you. Expect average daily highs of 80 ºF and nightly lows around 75 ºF.
Travel tips for Sao Tome and Principe

  • Sao Tome and Principe has dozens of wonderful attractions and Market is one of them. Pick up a car rental and head there at your own speed.
  • Sao Tome Island offers tons of one-of-a-kind experiences and is a top place to kick off your vacation. Whether you're into art, cafés, restaurants or something else, this city will keep you entertained.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.