$89 Cheap flights to New Madrid County

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Cheap flights to New Madrid County from $89 One Way, $183 Round Trip

$183 return flights and $89 one-way flights to New Madrid County were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Sep 3 - Mon, Sep 7
ORD
Chicago
CGI
Cape Girardeau
$183 Roundtrip, found 11 hours ago
$183
Roundtrip
found 11 hours ago
Select Contour Airlines flight, departing Thu, Sep 3 from Chicago to Cape Girardeau, returning Mon, Sep 7, priced at $183 found 11 hours ago
Thu, Aug 27 - Mon, Aug 31
ORD
Chicago
CGI
Cape Girardeau
$185 Roundtrip, found 20 hours ago
$185
Roundtrip
found 20 hours ago
Select Contour Airlines flight, departing Thu, Aug 27 from Chicago to Cape Girardeau, returning Mon, Aug 31, priced at $185 found 20 hours ago
Fri, Sep 4 - Mon, Sep 7
ORD
Chicago
CGI
Cape Girardeau
$216 Roundtrip, found 11 hours ago
$216
Roundtrip
found 11 hours ago
Select Contour Airlines flight, departing Fri, Sep 4 from Chicago to Cape Girardeau, returning Mon, Sep 7, priced at $216 found 11 hours ago
Fri, Sep 18 - Sun, Sep 20
DFW
Dallas
CGI
Cape Girardeau
$226 Roundtrip, found 1 day ago
$226
Roundtrip
found 1 day ago
Select Contour Airlines flight, departing Fri, Sep 18 from Dallas to Cape Girardeau, returning Sun, Sep 20, priced at $226 found 1 day ago
Mon, Dec 7 - Thu, Dec 10
LGA
New York
CGI
Cape Girardeau
$529 Roundtrip, found 3 days ago
$529
Roundtrip
found 3 days ago
Select Delta flight, departing Mon, Dec 7 from New York to Cape Girardeau, returning Thu, Dec 10, priced at $529 found 3 days ago
Mon, Dec 7 - Thu, Dec 10
JFK
New York
CGI
Cape Girardeau
$573 Roundtrip, found 3 days ago
$573
Roundtrip
found 3 days ago
Select American Airlines flight, departing Mon, Dec 7 from New York to Cape Girardeau, returning Thu, Dec 10, priced at $573 found 3 days ago
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Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
ORDScott CityAugust 21 to August 23$185
ORDScott CityAugust 21 to August 23$185
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic New Madrid County Accommodation Deals

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
Fully refundable
$97 nightly
The price is $110 total per night from Aug 23 to Aug 24
$110 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
Opens in a new windowHoliday Inn Express & Suites Sikeston Southwest by IHG
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$98 nightly
The price is $110 total per night from Aug 23 to Aug 24
$110 total
Aug 23 - Aug 24
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
9/10 Wonderful! (607 reviews)
"Hotel was nice but unfortunately someone decided to smoke in the elevator one night which made it shut down. So, until the repair was completed, everyone one the upper floors had to take the stairs down multiple floors. Usually not that big of an issue, but we were there for a bike ride and had to ..."

Reviewed on Aug 10, 2026

Opens in a new windowHampton Inn Sikeston
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

3 out of 5
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Aug 23 to Aug 24
$114 total
Aug 23 - Aug 24
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
9.4/10 Exceptional! (103 reviews)
"Staff were excellent! Very personable with us!"

Reviewed on Aug 12, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Sikeston
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New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61 Portageville MO
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (797 reviews)
"When I checked in, my key didn't work at all and had to be let in by staff, who was not there the rest of the night, so I was basically stuck in my room from 7pm to the time I left, which wasn't great. The room was relatively clean, the carpet seemed new. The room did feel humid and the bed was covered ..."

Reviewed on Aug 11, 2026

Get rates
Opens in a new windowNew Orleans Inn Portageville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

New Madrid County

Orbitz uses cutting edge mobile technology to help get you the best deals on New Madrid County flights. We offer guaranteed low prices on air tickets that can be combined with hotels and car rentals to save you even more money.

Find Cheap New Madrid County Flights And Hotel Rooms Using Our Mobile App

Orbitz not only guarantees low prices for flights to New Madrid County, we also offer Mobile Steals on our Orbitz on the Go mobile app where you can find great mobile-only deals on hotel rooms in the area.

Use the Orbitz Flight Matrix To Save Big On Car Rental

Discount flights to New Madrid County can be combined with car rental to get you additional savings. Just use our Flight Matrix to see how your budget air ticket can be combined with a car rental to make your trip not only inexpensive but also more convenient.

Use Multiple Airlines To Ensure You Get The Best Deal

Orbitz allows you to use multiple airlines for flights to New Madrid County. By using a combination of airlines for discount flights you are guaranteed to get the lowest fares each way and get the schedule that is most convenient for you.

Store Your Frequent Flyer Information on Orbitz For Easy Access

Booking with Orbitz will still allow you to apply miles for flights to New Madrid County to your frequent flyer program. Not only that, but your frequent flyer information will be safely stored on our website, so it will be easy to access the next time you book a discount air ticket with Orbitz.

Frequently asked questions

Which airlines fly to New Madrid County?
Look up the deals from the 12 airlines that provide services to New Madrid County. Whether you want to sip Champagne in the pointy end of the plane or save money in economy, there'll be a seat for you. Head for Lambert-St. Louis Intl. Airport (STL) with one of these reputable carriers:

  • Air Canada - 35 flights to New Madrid County per month
  • Frontier Airlines - 17 flights to New Madrid County per month
  • Lufthansa - 3 flights to New Madrid County per month

How much is a flight to New Madrid County?
Prices for round-trip flights fell as low as $183 this past week to New Madrid County, and went as high as $573. Travelers flying out of Chicago (ORD) managed to score one-way fares starting at just $89.
How to book the cheapest flight to New Madrid County?
With Orbitz, you'll find some of the most incredible flight deals around from a wide selection of airlines. But if you'd like to increase your chances of picking up cheap flights to New Madrid County, here are some tips designed to help:

  • Consider other airports to cut costs. Enter your preferred departure and arrival points in the form fields, then click on the 'Nearby airports' function below. It will show you any available options.
  • If you're flexible with when you take off, click on the 'Show flexible dates' option. You'll see the flight deals for the days before and after your chosen departure. Airfares often vary depending on what day it is.
  • You can also select the 'Show options' link to filter results for your preferred airline, seating class, and nonstop and refundable flights. Under 'Sort & Filter' to the left, you can even pick the time of day you want to fly.
  • Reserve your airfare as soon as you've worked out your travel dates. While it does happen on occasion, airline tickets rarely drop in price as your date of departure gets closer.
  • Combine your hotels, flights and car rentals into a value-for-money package deal. Save your hard-earned money for things that really excite you, like exploring every corner of New Madrid County.
  • Flying during busier seasons often means costly airfares. Try to avoid traveling over popular periods, such as Christmas, New Year's Eve and Easter.

What is the best time to book a flight to New Madrid County?
Pick up a bargain and book your seats to New Madrid County in January. If you've missed this month, fear not. February and August often have low airfares as well. Just be careful you don't sleep on a sale though — cheap flights pop up and disappear in the blink of an eye!
What day of the week is the cheapest to book a flight to New Madrid County?
Typically, Tuesdays, Wednesdays and Saturdays are the cheapest days of the week to book flights to New Madrid County. If you're after the best airfares, search across those days and you're likely to land yourself an excellent flight deal.
What is the cheapest day of the week to fly to New Madrid County?
Based on Orbitz data from 2020, Monday is generally the best day of the week for cheap flights to New Madrid County. Tuesday also offers more affordable fares, whereas Saturday has the highest ticket rates. Although flying out at the weekend may be easier to organize, you'll have more money in your pocket to play with if you fly out at the start of the week.
What is the cheapest month to fly to New Madrid County?
Consider jetting off sometime in August if you don't want to eat into your budget. Orbitz data shows that this is generally the best month for cheap flights to New Madrid County. June is when prices really go up.
Which airlines allow free cancellation?
We know that plans can change and flexibility is more important than ever. That's why you can search for flights that have free cancellation and no change fees on Orbitz. Just click on "Filter by flexible change policies" and we'll find you fares more flexible than candy in a hot car!
What do I need for the flight to New Madrid County?
Flying can be fun with a little pre-planning! Make your flight a total breeze with the following handy hints:

  • Whether you print it out or use an electronic one, you'll need your boarding pass to walk on to the plane. You'll also need some form of government-issued photo identification. If you're traveling internationally, make sure your passport is valid and you've checked visa requirements.
  • Take some activities to keep you amused on your journey to New Madrid County. Magazines and electronic gadgets like tablets and e-readers are perfect. Be sure to take a refillable water bottle with you as well. Even on a short flight, it's important to stay well-hydrated.
  • Even if you're flying when it's sweltering outside, carry a cardigan or sweater on board with you. Airplane cabins can get downright cold.

How do I get cheap first-class/business deals to New Madrid County?
There are ways of booking business or first-class fares to New Madrid County that won't burn a hole through your budget. Find a seat in the pointy end of the plane for less with these helpful tips:

  • Be more flexible with your travel dates and hold out for deals on business or first-class airfares.
  • Budget airlines offer business-class seats at more affordable prices. Ditch the full-service carriers and look into these cheaper options.
  • Make a bid for an upgrade. Some airlines hold online auctions that let you offer a price for a seat at the front of the plane. You may also be able to upgrade with points earned through a flight loyalty scheme.

What is the best time to go to New Madrid County?
New Madrid County is an excellent vacation destination year-round, but the most popular months to visit are June, August and October. If you're into warm weather, visit during the summer. Like most destinations in the Northern Hemisphere, the summer season kicks off June 20. Temperatures normally range between 70 ºF and 85 ºF during the daytime.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.