$99 Cheap flights to New Madrid County

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap flights to New Madrid County from $99 One Way, $198 Round Trip

$198 return flights and $99 one-way flights to New Madrid County were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Oct 22 - Wed, Oct 28
ORD
Chicago
CGI
Cape Girardeau
$198 Roundtrip, found 13 hours ago
$198
Roundtrip
found 13 hours ago
Select Contour Airlines flight, departing Thu, Oct 22 from Chicago to Cape Girardeau, returning Wed, Oct 28, priced at $198 found 13 hours ago
Tue, Oct 13 - Tue, Oct 20
ORD
Chicago
CGI
Cape Girardeau
$201 Roundtrip, found 1 day ago
$201
Roundtrip
found 1 day ago
Select Contour Airlines flight, departing Tue, Oct 13 from Chicago to Cape Girardeau, returning Tue, Oct 20, priced at $201 found 1 day ago
Sat, Oct 31 - Wed, Nov 11
ORD
Chicago
CGI
Cape Girardeau
$218 Roundtrip, found 8 hours ago
$218
Roundtrip
found 8 hours ago
Select Contour Airlines flight, departing Sat, Oct 31 from Chicago to Cape Girardeau, returning Wed, Nov 11, priced at $218 found 8 hours ago
Mon, Oct 19 - Thu, Oct 22
DFW
Dallas
CGI
Cape Girardeau
$238 Roundtrip, found 3 days ago
$238
Roundtrip
found 3 days ago
Select Contour Airlines flight, departing Mon, Oct 19 from Dallas to Cape Girardeau, returning Thu, Oct 22, priced at $238 found 3 days ago
Tue, Dec 29 - Tue, Jan 5
PHX
Phoenix
CGI
Cape Girardeau
$606 Roundtrip, found 5 days ago
$606
Roundtrip
found 5 days ago
Select Delta flight, departing Tue, Dec 29 from Phoenix to Cape Girardeau, returning Tue, Jan 5, priced at $606 found 5 days ago
Thu, Oct 8 - Mon, Oct 12
MCO
Orlando
CGI
Cape Girardeau
$733 Roundtrip, found 12 hours ago
$733
Roundtrip
found 12 hours ago
Select American Airlines flight, departing Thu, Oct 8 from Orlando to Cape Girardeau, returning Mon, Oct 12, priced at $733 found 12 hours ago

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
ORDScott CityOctober 2 to October 4$393
ORDScott CityOctober 2 to October 4$393
JFKScott CityOctober 4 to October 11$743
MCOScott CityOctober 3 to October 7$1,255
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Score Epic New Madrid County Accommodation Deals

Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 out of 5
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $115 total per night from Oct 11 to Oct 12
$115 total
Oct 11 - Oct 12
Total with taxes and fees
Stay at this hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions Central ...
9/10 Wonderful! (624 reviews)
"Staff was great"

Reviewed on Sep 22, 2026

Opens in a new windowHampton Inn Sikeston
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 out of 5
600 US-61 Portageville MO
Stay at this motel in Portageville. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
8/10 Very Good! (798 reviews)
"Plain outside, nice room, inside of microwave had rust, smoke detector missing, very low price was nice."

Reviewed on Sep 15, 2026

Get rates
Opens in a new windowNew Orleans Inn Portageville
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

3 out of 5
1239 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $114 total per night from Oct 11 to Oct 12
$114 total
Oct 11 - Oct 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Central Park and Sikeston Depot ...
Opens in a new windowFairfield Inn & Suites by Marriott Sikeston
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 out of 5
115 Hospitality Dr Sikeston MO
Fully refundable
$101 nightly
The price is $114 total per night from Oct 4 to Oct 5
$114 total
Oct 4 - Oct 5
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.8/10 Excellent! (512 reviews)
"This was our second time staying we enjoyed ourselves. The area is peaceful."

Reviewed on Sep 28, 2026

Opens in a new windowHoliday Inn Express & Suites Sikeston Southwest by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

New Madrid County

Start your search for cheap flights to New Madrid County on Orbitz. Orbitz is where you will discover guaranteed low prices on New Madrid County flights, as well as all of the following conveniences:

Travel Updates on Your Mobile Device

Orbitz offers cutting-edge mobile tools for your smartphone. Whether you own an iPhone or an Android phone, you can benefit from Orbitz’s flight status updates and even book your future New Madrid County flights. You can also review and reserve hotel rooms for when your New Madrid County flights land and see other special offers.

Low Prices Guaranteed on Flights to New Madrid County

Orbitz offers large discounts on a wide range of New Madrid County flights. Through our easy-to-use site, you can find, plan, and reserve your desired flights to New Madrid County while taking advantage of the lowest fares around.

Customer Care When You Need It

Orbitz is dedicated to making your flight booking experience as stress-free as possible. If you need to cancel your reservation, you can do so at your own convenience by going to the Orbitz website. If you need to change your flights to New Madrid County to another time or date, you can contact our customer service representatives by phone, and they help you make the flight adjustments you need.

Loyalty Program Participation Opportunities

Orbitz lets you add your loyalty or frequent flyer account numbers when you book qualifying flights to New Madrid County. So don’t worry about missing out on earning miles or points simply because you aren’t booking with the airline directly. You can save on your flights, and rack up miles too.

Frequently asked questions

Which airlines fly to New Madrid County?
Look up the deals from the 12 airlines that provide services to New Madrid County. Whether you want to sip Champagne in the pointy end of the plane or save money in economy, there'll be a seat for you. Head for Lambert-St. Louis Intl. Airport (STL) with one of these reputable carriers:

  • Air Canada - 35 flights to New Madrid County per month
  • Frontier Airlines - 17 flights to New Madrid County per month
  • Lufthansa - 3 flights to New Madrid County per month

How much is a flight to New Madrid County?
Prices for round-trip flights fell as low as $198 this past week to New Madrid County, and went as high as $1,255. Travelers flying out of Chicago (ORD) managed to score one-way fares starting at just $99.
How to book the cheapest flight to New Madrid County?
With Orbitz, you'll find some of the most incredible flight deals around from a wide selection of airlines. But if you'd like to increase your chances of picking up cheap flights to New Madrid County, here are some tips designed to help:

  • Consider other airports to cut costs. Enter your preferred departure and arrival points in the form fields, then click on the 'Nearby airports' function below. It will show you any available options.
  • If you're flexible with when you take off, click on the 'Show flexible dates' option. You'll see the flight deals for the days before and after your chosen departure. Airfares often vary depending on what day it is.
  • You can also select the 'Show options' link to filter results for your preferred airline, seating class, and nonstop and refundable flights. Under 'Sort & Filter' to the left, you can even pick the time of day you want to fly.
  • Reserve your airfare as soon as you've worked out your travel dates. While it does happen on occasion, airline tickets rarely drop in price as your date of departure gets closer.
  • Combine your hotels, flights and car rentals into a value-for-money package deal. Save your hard-earned money for things that really excite you, like exploring every corner of New Madrid County.
  • Flying during busier seasons often means costly airfares. Try to avoid traveling over popular periods, such as Christmas, New Year's Eve and Easter.

What is the best time to book a flight to New Madrid County?
Pick up a bargain and book your seats to New Madrid County in January. If you've missed this month, fear not. February and August often have low airfares as well. Just be careful you don't sleep on a sale though — cheap flights pop up and disappear in the blink of an eye!
What day of the week is the cheapest to book a flight to New Madrid County?
Typically, Tuesdays, Wednesdays and Saturdays are the cheapest days of the week to book flights to New Madrid County. If you're after the best airfares, search across those days and you're likely to land yourself an excellent flight deal.
What is the cheapest day of the week to fly to New Madrid County?
Based on Orbitz data from 2020, Monday is generally the best day of the week for cheap flights to New Madrid County. Tuesday also offers more affordable fares, whereas Saturday has the highest ticket rates. Although flying out at the weekend may be easier to organize, you'll have more money in your pocket to play with if you fly out at the start of the week.
What is the cheapest month to fly to New Madrid County?
Consider jetting off sometime in August if you don't want to eat into your budget. Orbitz data shows that this is generally the best month for cheap flights to New Madrid County. June is when prices really go up.
Which airlines allow free cancellation?
We know that plans can change and flexibility is more important than ever. That's why you can search for flights that have free cancellation and no change fees on Orbitz. Just click on "Filter by flexible change policies" and we'll find you fares more flexible than candy in a hot car!
What do I need for the flight to New Madrid County?
Flying can be fun with a little pre-planning! Make your flight a total breeze with the following handy hints:

  • Whether you print it out or use an electronic one, you'll need your boarding pass to walk on to the plane. You'll also need some form of government-issued photo identification. If you're traveling internationally, make sure your passport is valid and you've checked visa requirements.
  • Take some activities to keep you amused on your journey to New Madrid County. Magazines and electronic gadgets like tablets and e-readers are perfect. Be sure to take a refillable water bottle with you as well. Even on a short flight, it's important to stay well-hydrated.
  • Even if you're flying when it's sweltering outside, carry a cardigan or sweater on board with you. Airplane cabins can get downright cold.

How do I get cheap first-class/business deals to New Madrid County?
There are ways of booking business or first-class fares to New Madrid County that won't burn a hole through your budget. Find a seat in the pointy end of the plane for less with these helpful tips:

  • Be more flexible with your travel dates and hold out for deals on business or first-class airfares.
  • Budget airlines offer business-class seats at more affordable prices. Ditch the full-service carriers and look into these cheaper options.
  • Make a bid for an upgrade. Some airlines hold online auctions that let you offer a price for a seat at the front of the plane. You may also be able to upgrade with points earned through a flight loyalty scheme.

What is the best time to go to New Madrid County?
New Madrid County is an excellent vacation destination year-round, but the most popular months to visit are June, August and October. If you're into warm weather, visit during the summer. Like most destinations in the Northern Hemisphere, the summer season kicks off June 20. Temperatures normally range between 70 ºF and 85 ºF during the daytime.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.