$99 Cheap flights to Mississippi County

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Top places to visit in Mississippi County

A sunset over a calm lake with tall trees reflected in the water.
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Charleston

Charleston
A tree-lined landscape with a river and fields.
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FlightsFlights

East Prairie

East Prairie

Cheap flights to Mississippi County from $99 One Way, $194 Round Trip

$194 return flights and $99 one-way flights to Mississippi County were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Wed, Jun 30 - Wed, Jul 7
ORD
Chicago
PAH
Paducah
$194 Roundtrip, found 4 days ago
$194
Roundtrip
found 4 days ago
Select United flight, departing Wed, Jun 30 from Chicago to Paducah, returning Wed, Jul 7, priced at $194 found 4 days ago
Thu, Oct 22 - Sun, Oct 25
ORD
Chicago
PAH
Paducah
$197 Roundtrip, found 1 day ago
$197
Roundtrip
found 1 day ago
Select United flight, departing Thu, Oct 22 from Chicago to Paducah, returning Sun, Oct 25, priced at $197 found 1 day ago
Thu, Nov 26 - Sat, Nov 28
ORD
Chicago
CGI
Cape Girardeau
$198 Roundtrip, found 17 hours ago
$198
Roundtrip
found 17 hours ago
Select Contour Airlines flight, departing Thu, Nov 26 from Chicago to Cape Girardeau, returning Sat, Nov 28, priced at $198 found 17 hours ago
Wed, Oct 7 - Sun, Oct 11
ORD
Chicago
CGI
Cape Girardeau
$201 Roundtrip, found 16 hours ago
$201
Roundtrip
found 16 hours ago
Select Contour Airlines flight, departing Wed, Oct 7 from Chicago to Cape Girardeau, returning Sun, Oct 11, priced at $201 found 16 hours ago
Wed, Nov 25 - Sat, Nov 28
ORD
Chicago
CGI
Cape Girardeau
$218 Roundtrip, found 17 hours ago
$218
Roundtrip
found 17 hours ago
Select Contour Airlines flight, departing Wed, Nov 25 from Chicago to Cape Girardeau, returning Sat, Nov 28, priced at $218 found 17 hours ago
Sat, Oct 10 - Mon, Oct 12
ORD
Chicago
CGI
Cape Girardeau
$222 Roundtrip, found 5 days ago
$222
Roundtrip
found 5 days ago
Select Contour Airlines flight, departing Sat, Oct 10 from Chicago to Cape Girardeau, returning Mon, Oct 12, priced at $222 found 5 days ago

Deals For This Weekend's Flights

Find The Perfect Hotel For After Your Flight

Score Epic Mississippi County Accommodation Deals

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

2 out of 5
310 S Story St Charleston MO
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $66 total per night from Sep 23 to Sep 24
$66 total
Sep 23 - Sep 24
Total with taxes and fees
Stay at this motel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews.
6.8/10 (669 reviews)
"Súper affordable pricing, and the property was clean and comfortable! Complimentary breakfast was a plus!"

Reviewed on Sep 21, 2026

Opens in a new windowSuper 8 by Wyndham Charleston/Sikeston East MO
The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston

2.5 out of 5
102 Drake St Charleston MO
Fully refundable
$66 nightly
The price is $74 total per night from Sep 24 to Sep 25
$74 total
Sep 24 - Sep 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Charleston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the property condition in our ...
6.8/10 (434 reviews)
"Appalled at the number of big beetles inside the hotel room. The bathroom didn't look like it had been cleaned and I was horrified when another beetle crawled across the floor as I was stepping out of the shower. I didn't get to rest a and I expected a better experience for paying $120 for the ..."

Reviewed on Sep 16, 2026

Opens in a new windowThe Riverstone Hotel Charleston-Sikeston
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3 out of 5
2608 East Malone Ave, Miner Sikeston MO
Fully refundableReserve now, pay when you stay
$94 nightly
The price is $108 total per night from Sep 27 to Sep 28
$108 total
Sep 27 - Sep 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
Opens in a new windowDrury Inn & Suites Sikeston, MO
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Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

2 out of 5
220 S Interstate Dr Sikeston MO
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $76 total per night from Sep 24 to Sep 25
$76 total
Sep 24 - Sep 25
Total with taxes and fees
Book a stay at this business-friendly hotel in Sikeston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,007 reviews)
"This was a very good value. It has been the best hotel I've stayed at in awhile."

Reviewed on Sep 21, 2026

Opens in a new windowDays Inn and Suites by Wyndham Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

Mississippi County

Start your search for cheap flights to Mississippi County on Orbitz. Orbitz is where you will discover guaranteed low prices on Mississippi County flights, as well as all of the following conveniences:

Travel Updates on Your Mobile Device

Orbitz offers cutting-edge mobile tools for your smartphone. Whether you own an iPhone or an Android phone, you can benefit from Orbitz’s flight status updates and even book your future Mississippi County flights. You can also review and reserve hotel rooms for when your Mississippi County flights land and see other special offers.

Low Prices Guaranteed on Flights to Mississippi County

Orbitz offers large discounts on a wide range of Mississippi County flights. Through our easy-to-use site, you can find, plan, and reserve your desired flights to Mississippi County while taking advantage of the lowest fares around.

Customer Care When You Need It

Orbitz is dedicated to making your flight booking experience as stress-free as possible. If you need to cancel your reservation, you can do so at your own convenience by going to the Orbitz website. If you need to change your flights to Mississippi County to another time or date, you can contact our customer service representatives by phone, and they help you make the flight adjustments you need.

Loyalty Program Participation Opportunities

Orbitz lets you add your loyalty or frequent flyer account numbers when you book qualifying flights to Mississippi County. So don’t worry about missing out on earning miles or points simply because you aren’t booking with the airline directly. You can save on your flights, and rack up miles too.

Frequently asked questions

Which airlines fly to Mississippi County?
Reserve a ticket with one of the 12 airlines that operate services to Nashville Intl. Airport (BNA) and come prepared for exciting new adventures. This popular airport is a major entrance point for Mississippi County. When you're ready to see this region, these reputable carriers will get you there:

  • Air Canada - 42 flights to Mississippi County per month
  • WestJet - 20 flights to Mississippi County per month
  • British Airways - 16 flights to Mississippi County per month

How much is a flight to Mississippi County?
Prices for return flights to Mississippi County this past week fluctuated from $194 to $222. If you were traveling one-way from Chicago (ORD), you could have snapped up tickets from as low as $99.
How to book the cheapest flight to Mississippi County?
Scoring cheap flights to Mississippi County is as easy as booking with Orbitz. But if you'd like to make sure you're walking away with the best flight deals around, here are some tips worth following:

  • Consider taking off from or landing at other airports to cut costs. Enter your preferred departure and arrival points in the form fields, then choose the 'Nearby airports' function below. It will list any available options.
  • If your travel plans aren't etched in stone, click on the 'Show flexible dates' link to see the flight deals across different departure dates. You may find a cheaper fare.
  • Hit 'Show options' to filter your search results. You can choose your preferred airline and seating class here. Under 'Sort & Filter' to the left, you can even select whether you want to fly in the morning, afternoon or evening.
  • Reserve your seat as soon as you've figured out your travel dates. While it does happen on occasion, tickets rarely fall in price as your departure date nears.
  • Save even more on your trip by bundling your hotel, flights and car rental into a package. Your wallet will thank you.
  • Don't fly during peak seasons if possible. By steering clear of school vacations and summer, you can save big on your airfare.

What is the best time to book a flight to Mississippi County?
Pick up a bargain and book your tickets to Mississippi County in January. If you've missed this month, don't stress. February and August often have affordable airfares too. Be careful not to sleep on a sale though — cheap flights emerge and disappear in a flash!
What day of the week is the cheapest to book a flight to Mississippi County?
Typically, Tuesdays, Wednesdays and Saturdays are the cheapest days of the week to book flights to Mississippi County. If you're looking for unbeatable airfares, search across those days and you're likely to pick up a fantastic flight deal.
What is the cheapest day of the week to fly to Mississippi County?
You can pick up cheap flights to Mississippi County by taking to the skies on a Monday, according to Orbitz data from 2020. Tuesday is also more affordable, while Saturday has the most costly ticket prices. Whether you prefer to save money or start your trip on any day that's convenient, you'll always find a rewarding deal with Orbitz.
What is the cheapest month to fly to Mississippi County?
To secure cheap flights to Mississippi County, you should take off in August. If getting a great deal on your ticket is your number one priority, Orbitz data shows that this is generally an excellent month to take a trip. June is when fares are at their peak.
Which airlines allow free cancellation?
If you're worried your travel plans may change, Orbitz will help you find a flexible fare. All you have to do is select "Filter by flexible change policies" when searching for your flights. We'll show you airlines that include free cancellation and no change fees — all on top of our awesome low prices.
What do I need for the flight to Mississippi County?
The secret to a comfortable and stress-free flight is being well prepared. Listed below are some handy tips to help you get ready for your trip:

  • Your travel documents are the most important things you'll need to have with you on your flight. To avoid any issues during check-in, make sure that the personal information on your ticket is correct and matches your government-issued ID.
  • Take some activities to pass the time on your journey to Mississippi County. Books and electronic devices like e-readers and laptops are perfect. Don't forget to take a bottle of water as well. Even on a short flight, it's important to keep hydrated.
  • No matter the weather outside, plane cabins can get cold. Take a sweater on board to keep yourself cozy.

How do I get cheap first-class/business deals to Mississippi County?
Experienced travelers are pros at finding first or business-class airfares to Mississippi County without the astronomical price tag. You can do the same with these useful hints:

  • Flexibility is essential. By being open to a variety of travel dates, you'll have better odds of spotting a sale on business or first-class airfares.
  • Many low-cost airlines these days have quality business or premium-class seating that doesn't cost an arm and a leg.
  • Make the most of your airline's loyalty program and upgrade your seat. Alternatively, you can try bidding for an upgrade in an online auction.

What is the best time to go to Mississippi County?
If you want to soak up the culture of Mississippi County in the tourist season, March, April and June are the prime months to visit. June 20 marks the beginning of summertime in the Northern Hemisphere and is a perfect time to go if you relish the open air. Around this time of year, average daily temperatures generally range from 70 ºF to 85 ºF.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.