$22 Cheap flights to Madre de Dios Region

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Cheap flights to Madre de Dios Region from $22 One Way, $51 Round Trip

$51 return flights and $22 one-way flights to Madre de Dios Region were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Fri, Aug 8 - Mon, Aug 11
CUZ
Cusco
PEM
Puerto Maldonado
$51 Roundtrip, found 5 days ago
$51
Roundtrip
found 5 days ago
Select SKY AIRLINE flight, departing Fri, Aug 8 from Cusco to Puerto Maldonado, returning Mon, Aug 11, priced at $51 found 5 days ago
Mon, Dec 29 - Sun, Jan 4
CUZ
Cusco
PEM
Puerto Maldonado
$53 Roundtrip, found 5 hours ago
$53
Roundtrip
found 5 hours ago
Select SKY AIRLINE flight, departing Mon, Dec 29 from Cusco to Puerto Maldonado, returning Sun, Jan 4, priced at $53 found 5 hours ago
Mon, Dec 29 - Sun, Jan 4
CUZ
Cusco
PEM
Puerto Maldonado
$90 Roundtrip, found 5 hours ago
$90
Roundtrip
found 5 hours ago
Select LATAM Airlines Group flight, departing Mon, Dec 29 from Cusco to Puerto Maldonado, returning Sun, Jan 4, priced at $90 found 5 hours ago
Sun, Oct 19 - Wed, Oct 22
LIM
Lima
PEM
Puerto Maldonado
$97 Roundtrip, found 1 day ago
$97
Roundtrip
found 1 day ago
Select SKY AIRLINE flight, departing Sun, Oct 19 from Lima to Puerto Maldonado, returning Wed, Oct 22, priced at $97 found 1 day ago
Thu, Aug 14 - Wed, Aug 20
MBJ
Montego Bay
PEM
Puerto Maldonado
$530 Roundtrip, found 1 day ago
$530
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Thu, Aug 14 from Montego Bay to Puerto Maldonado, returning Wed, Aug 20, priced at $530 found 1 day ago
Fri, Apr 3 - Sun, Apr 12
JFK
New York
PEM
Puerto Maldonado
$674 Roundtrip, found 1 day ago
$674
Roundtrip
found 1 day ago
Select LATAM Airlines Group flight, departing Fri, Apr 3 from New York to Puerto Maldonado, returning Sun, Apr 12, priced at $674 found 1 day ago

Deals For This Weekend's Flights

OriginDestinationTravel DatesFlights From*
LIMTambopataJuly 18 to July 21$143
*Prices include taxes and fees

Find The Perfect Hotel For After Your Flight

Our Top Madre de Dios Region Apartment Hotels

CHIMICUAS HOUSE

CHIMICUAS HOUSE

3.5 out of 5
Jr. Atahuallpa cdra 8 Con Jr., La Pradera Puerto Maldonado, Tambopata, Madre de Dios
Stay at this 3.5-star business-friendly hotel in Tambopata. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Puerto Maldonado Obelisk and ...
"Very pleasant welcome to the city. Hospitable and very friendly.great place to come to after or before going to the jungle"

Reviewed on Oct 14, 2016

Get rates
CHIMICUAS HOUSE
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Score Epic Madre de Dios Region Accommodation Deals

Dmilez Hotel

Dmilez Hotel

2.5 out of 5
Psj. Tupac Amaru, Mz. E, Lot 6, A.H.8 de Octubre, Tambopata, Madre de Dios
Fully refundableReserve now, pay when you stay
$34 nightly
The price is $34 total per night from Jul 28 to Jul 29
$34 total
Jul 28 - Jul 29
Book a stay at this business-friendly hotel in Tambopata. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Puerto Maldonado Obelisk and ...
6.6/10 (20 reviews)
"5 stories, no elevator, could not communicate with desk staff in english or basic spanish"

Reviewed on Oct 21, 2024

Dmilez Hotel
IKAM Riverview Amazon Lodge - Asociado Casa Andina

IKAM Riverview Amazon Lodge - Asociado Casa Andina

3 out of 5
Tambopata KM. 7 Otr. Carretera Bajo, Tambopata, Madre de Dios
$258 nightly
The price is $258 total per night from Jul 14 to Jul 15
$258 total
Jul 14 - Jul 15
Stay at this 3-star all-inclusive hotel in Tambopata. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Puerto Capitanía and Puerto Maldonado ...
9/10 Wonderful! (4 reviews)
"Beautiful location on the river, staff and guides were great, the ask inclusive feature was very convenient. A little bit difficult to get to but would recommend. Food was average but service and attentiveness made up for it."

Reviewed on May 25, 2025

IKAM Riverview Amazon Lodge - Asociado Casa Andina
Libelula Hotel

Libelula Hotel

2 out of 5
Jr Puno No. 429, Tambopata, Madre de Dios
Fully refundableReserve now, pay when you stay
Stay at this hostal in Tambopata. Enjoy free WiFi, daily housekeeping, and cable TV channels. Popular attractions Puerto Maldonado Plaza de Armas and Maldonado ...
9.4/10 Exceptional! (15 reviews)
"Great stay, friendly owners and staff."

Reviewed on Jun 22, 2025

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Libelula Hotel
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La Fauna Hotel

La Fauna Hotel

2 out of 5
Jr Arequipa 441, Tambopata
Stay at this hostel in Tambopata. Enjoy free breakfast, free WiFi, and daily housekeeping. Popular attractions Puerto Maldonado Plaza de Armas and Maldonado ...
9.6/10 Exceptional! (6 reviews)
"Staff and location made it exceptional"

Reviewed on May 21, 2025

Get rates
La Fauna Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Madre de Dios Region

Refugio Amazonas
Great for families

Refugio Amazonas

3 out of 5
Rio Tambopata, Tambopata, Madre de Dios
$751 nightly
The price is $751 total per night from Jul 15 to Jul 16
$751 total
Jul 15 - Jul 16
Stay at this 3-star family-friendly inn in Tambopata. Enjoy a free airport shuttle, onsite spa services, and a 24-hour front desk. Popular attraction Lac Sachavacayoc ...

Families like: Kids club, playground, babysitting, bicycle rentals

Travelers say...
"Our experience was amazing! This was an experience that I have always dreamed about. The guides for the excursions were the best. They were so knowledgeable and friendly. I will never forget all the beautiful sounds that you wake up to in the rainforest. The lodge was very eco friendly and the rooms ..."

Reviewed on Apr 4, 2022

Refugio Amazonas
Andean Wings Sotupa Eco Lodge
Great for families

Andean Wings Sotupa Eco Lodge

2 out of 5
Carretera Tambopata Km 11,5, Bajo Tambopata, Tambopata, Madre de Dios
Book a stay at this beach guesthouse in Tambopata. Enjoy free breakfast, free parking, and a free beach shuttle. Popular attractions Puerto Capitanía and Puerto ...
8/10 Very Good! (4 reviews)

Families like: Outdoor pool, game room, close to beach, bicycle rentals

Travelers say...
"The property itself is very well built we were surprised we had no issues with bugs inside the room! The view from our room was great also. This was our first time in PM so we didn’t know what to expect, but thought there would be more things to do there for what we paid. We also thought there would ..."

Reviewed on Apr 26, 2025

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Andean Wings Sotupa Eco Lodge
CHIMICUAS HOUSE

CHIMICUAS HOUSE

3.5 out of 5
Jr. Atahuallpa cdra 8 Con Jr., La Pradera Puerto Maldonado, Tambopata, Madre de Dios
Stay at this 3.5-star business-friendly hotel in Tambopata. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Puerto Maldonado Obelisk and ...
"Very pleasant welcome to the city. Hospitable and very friendly.great place to come to after or before going to the jungle"

Reviewed on Oct 14, 2016

Get rates
CHIMICUAS HOUSE
Save an average of 15% on thousands of hotels when you're signed in
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Ecolucerna Lodge Tambopata
Great for families

Ecolucerna Lodge Tambopata

2.5 out of 5
Rio Madre de Dios, Tambopata, Puerto Maldonado, Tambopata, Madre de Dios
Book a stay at this beach lodge in Tambopata. Enjoy free breakfast, room service, and an airport shuttle (surcharge).

Families like: Playground, game room, close to beach, free breakfast for the whole family

Travelers say...
"Boat ride to accommodation is long and it gets quite cold and windy in the boat"

Reviewed on Aug 27, 2024

Get rates
Ecolucerna Lodge Tambopata
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark or similar
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus or similar
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla or similar
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass or similar
  • 5 people
Jeep Compass
SUV Jeep Compass

Madre de Dios Region

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By using Orbitz’s free apps for iPhone and Android, and an easy-to-use mobile browser at m.orbitz.com, booking flights to Madre de Dios Region has never been so convenient. Check for updates and alerts wherever you are, or manage your booking quickly. And we also offer mobile exclusive deals on hotels, so don’t delay—book right away.

The Complete Package

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Low Price Guarantee

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Frequently asked questions

How much is a flight to Madre de Dios Region?
Round-trip flights to Madre de Dios Region this last week ranged between $51 and $674. If you were traveling one-way out of Cusco (CUZ), you could have snapped up ticket prices from just $22.
How to book the cheapest flight to Madre de Dios Region?
Scoring cheap flights to Madre de Dios Region is as simple as booking with Orbitz. But if you'd love to make sure you're walking away with the best flight deals around, here are some tips to keep your wallet happy:

  • Depending on where you're departing from, click on the 'Nearby airports' function (located under the departure and arrival form fields). At times, other departure points offer better value for money.
  • Similarly, click on the 'Show flexible dates' option and you'll see the airfares on days around your chosen departure. You may be able to find cheaper flight deals if you're flexible with your dates.
  • You can also select the 'Show options' function to filter results for your preferred airline, seating class, and nonstop and refundable flights. Under 'Sort & Filter' to the left, you can even pick the time of day you'd prefer to fly.
  • The early bird catches the best deals, so book as soon as you've worked out your travel dates. The most affordable fares get snapped up first and prices normally increase as the departure date nears.
  • Make serious savings on your vacation by bundling your hotel, flights and car rentals into an Orbitz package. Your travel budget will thank you.
  • Flying during the busy season can mean higher airfares. Try to avoid traveling over popular periods, such as Easter, Thanksgiving and school breaks.

What is the best time to book a flight to Madre de Dios Region?
Generally speaking, the cheapest time to purchase your airfare is in January. This is closely followed by February and August. When seeking a cheap flight to Madre de Dios Region, it's worth being ready to book. Cheap deals pop up suddenly and don't stick around!
What day of the week is the cheapest to book a flight to Madre de Dios Region?
Typically, Tuesdays, Wednesdays and Saturdays are the cheapest days to book a flight to Madre de Dios Region. If you want the most competitive airfares, search across those days and you're likely to catch an excellent flight deal.
What is the cheapest day of the week to fly to Madre de Dios Region?
If you're searching for cheap flights to Madre de Dios Region, leave early in the week. Orbitz data from 2020 shows Monday is the cheapest day to travel, followed by Tuesday. Saturday has the most expensive fares, so avoid flying on this day and do your budget a favor.
What is the cheapest month to fly to Madre de Dios Region?
Travel during August if you're on a budget. Orbitz data shows that this is generally the best month for cheap flights to Madre de Dios Region. June is when prices are at their most expensive.
Which airlines allow free cancellation?
When searching for flights on Orbitz, select "Filter by flexible change policies." This filter will show you all the airlines offering free cancellation within 24 hours of booking and no change fees. That means you can relax knowing that if things change, your flight can too.
What do I need for the flight to Madre de Dios Region?
The trick to having a smooth-sailing flight is to be prepared. Here are some tips to take note of before departure:

  • In all cases you'll need some identification. How much? This depends on where you're traveling from. When booking your flight tickets, we suggest to type in the same name, birth date and gender as written on your government-issued ID.
  • If you're flying directly to Madre de Dios Region, chances are you'll be in the air for quite a while. Pack lots of snacks and things to keep you occupied. Now is the perfect time to get stuck into that novel you've been eyeing off!
  • Cabin temperatures are often cold enough to give you goose pimples. Carry a sweater even if you're traveling during the height of summer.

How do I get cheap first-class/business deals to Madre de Dios Region?
Smart travelers have mastered the art of finding business or first-class airfares to Madre de Dios Region that don't cost a packet. Follow their example with these helpful tips:

  • Flexibility is essential. By being open to a variety of travel dates, you'll have more chances of picking up a deal on business or first-class airfares.
  • A lot of low-cost airlines have terrific business or premium-class seating that doesn't cost an arm and a leg.
  • Take advantage of your airline's flight rewards program and use points to upgrade your seat. You can also bid for an upgrade in an online auction.

What is the best time to go to Madre de Dios Region?
April, May and August is the most popular time to visit Madre de Dios Region. If you'd like to come when the weather's warmer, purchase your seats for summer. Temperatures typically average around 65 ºF in the evening and 75 ºF during the day at this time of year. Like many places in the Southern Hemisphere, the summer season in Madre de Dios Region begins December 1.
Travel tips for Madre de Dios Region

  • Aguas Calientes Hot Springs is just one of many must-see's while you're visiting Madre de Dios Region. Secure a car rental and enjoy the convenience of exploring this fabulous attraction --- and many others --- at your convenience.
  • One of Madre de Dios Region's most popular cities, Tambopata is the perfect place to start an epic road trip around this region. Eat, sleep, adventure and repeat --- that's what getaways are for!

City Destinations in Madre de Dios Region

Airlines Operating

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.