$69 Cheap flights to Knox County

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Cheap flights to Knox County from $69 One Way, $138 Round Trip

$138 return flights and $69 one-way flights to Knox County were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Thu, Sep 17 - Sun, Sep 20
ORD
Chicago
IRK
Kirksville
$138 Roundtrip, found 1 day ago
$138
Roundtrip
found 1 day ago
Select Contour Airlines flight, departing Thu, Sep 17 from Chicago to Kirksville, returning Sun, Sep 20, priced at $138 found 1 day ago
Fri, Aug 21 - Sun, Aug 23
ORD
Chicago
IRK
Kirksville
$142 Roundtrip, found 1 day ago
$142
Roundtrip
found 1 day ago
Select Contour Airlines flight, departing Fri, Aug 21 from Chicago to Kirksville, returning Sun, Aug 23, priced at $142 found 1 day ago
Fri, Sep 18 - Sun, Sep 20
ORD
Chicago
IRK
Kirksville
$153 Roundtrip, found 5 days ago
$153
Roundtrip
found 5 days ago
Select Contour Airlines flight, departing Fri, Sep 18 from Chicago to Kirksville, returning Sun, Sep 20, priced at $153 found 5 days ago
Sat, Nov 21 - Sat, Nov 28
ORD
Chicago
IRK
Kirksville
$168 Roundtrip, found 2 days ago
$168
Roundtrip
found 2 days ago
Select Contour Airlines flight, departing Sat, Nov 21 from Chicago to Kirksville, returning Sat, Nov 28, priced at $168 found 2 days ago
Fri, Aug 14 - Tue, Aug 18
ORD
Chicago
IRK
Kirksville
$177 Roundtrip, found 3 days ago
$177
Roundtrip
found 3 days ago
Select Contour Airlines flight, departing Fri, Aug 14 from Chicago to Kirksville, returning Tue, Aug 18, priced at $177 found 3 days ago
Fri, Aug 7 - Sun, Aug 9
DFW
Dallas
IRK
Kirksville
$218 Roundtrip, found 1 day ago
$218
Roundtrip
found 1 day ago
Select Contour Airlines flight, departing Fri, Aug 7 from Dallas to Kirksville, returning Sun, Aug 9, priced at $218 found 1 day ago

Deals For This Weekend's Flights

Find The Perfect Hotel For After Your Flight

Score Epic Knox County Accommodation Deals

Edina Missouri New Cabin in Rural Area

Edina Missouri New Cabin in Rural Area

Edina MO
Stay at this cabin in Edina. Enjoy free WiFi, laundry facilities, and patios.
10/10 Exceptional! (37 reviews)
"Clean functional property. Host was accommodating and very responsive to inquiries. Much appreciated. Would definitely stay here again."

Reviewed on May 18, 2026

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Opens in a new windowEdina Missouri New Cabin in Rural Area
Tiny Cozy Cottage in Edina, MO

Tiny Cozy Cottage in Edina, MO

Edina MO
The price is $102 total per night from Jul 8 to Jul 9
$102 total
per night
Jul 8 - Jul 9
Stay at this cottage in Edina. Enjoy free WiFi, a garden, and cable/satellite TV service.
10/10 Exceptional! (15 reviews)
"The cottage was clean and comfortable. It has a great shower and comfortble bed. Our son loved the smart tv and fold down bed. There are many thoughtful touches through out the cottage. It was a quick and easy drive to Kirksville. We highly recommend this property and will stay again when in the ..."

Reviewed on May 30, 2026

Opens in a new windowTiny Cozy Cottage in Edina, MO
Unique 2-bedroom house in Edina for a relaxing getaway

Unique 2-bedroom house in Edina for a relaxing getaway

Edina MO
The price is $103 total per night from Jul 14 to Jul 15
$103 total
per night
Jul 14 - Jul 15
Stay at this vacation home in Edina. Enjoy free WiFi, an in-room coffeemaker, and air conditioning.
10/10 Exceptional! (1 review)
"Very accommodating host. We had a dog, cat, plants, & enclosed trailer (moving). He was great to help us out when no one else had room for all this mess. Clean and comfortable. Excellent neighborhood for walking the dog."

Reviewed on Jun 13, 2026

Opens in a new windowUnique 2-bedroom house in Edina for a relaxing getaway
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Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area

2.5 out of 5
1101 Country Club Dr Kirksville MO
Fully refundableReserve now, pay when you stay
The price is $79 total per night from Jul 12 to Jul 13
$79 total
per night
Jul 12 - Jul 13
Book a stay at this golf hotel in Kirksville. Enjoy free breakfast, free WiFi, and free parking. Popular attraction Thousand Hills State Park is located ...
9/10 Wonderful! (237 reviews)
"The rooms were ok, had a very stale smell in the room, but seemed ok clean. Had a good view for the fireworks The breakfast was ok, the usual waffle maker, scrambled eggs and sausage nothing real special but ok. For the price it was ok"

Reviewed on Jul 4, 2026

Opens in a new windowSuper 8 by Wyndham Kirksville-University Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Need a Car For After Your Flight?

Economy

Chevrolet Spark
  • 4 people
Chevrolet Spark
Economy Chevrolet Spark

Compact

Ford Focus
  • 4 people
Ford Focus
Compact Ford Focus

Midsize

Toyota Corolla
  • 5 people
Toyota Corolla
Midsize Toyota Corolla

SUV

Jeep Compass
  • 5 people
Jeep Compass
SUV Jeep Compass

Knox County

Why search for low cost fares on your flights to Knox County when Orbitz offers the guaranteed lowest prices on foreign and domestic flights? When you travel with Orbitz you can benefit from:

Bargain Flights to Knox County

Orbitz offers massive discounts and substantial last-minute savings on your Knox County flights. Orbitz ensures that you can find, plan and reserve your flights any destination with ease, all while enjoying the guaranteed lowest prices available anywhere.

Cutting-Edge Mobile Tools to Keep You In The Know

Orbitz sends you free alerts and updates on your Knox County flight wherever you are in the world. Once you have downloaded the free app for your iPhone, Android, or iPad, you can review or alter any travel plans that you have made or even book a future flight for business or pleasure. If you need to reserve a hotel room when booking your flight, you will find exclusive deals on our mobile site.

Frequent Flyer Program Enrolment

Orbitz finds you the lowest fares, but you can still add your miles to your frequent flyer program to earn miles or points on selected flights to Knox County. When making your booking, reference your frequent flyer number to receive discounts in the future.

Outstanding Customer Service

Orbitz values your business and wants to ensure that all of your flights are as easy as possible to book. If you have booked a flight to Knox County but need to cancel it, you may be able to do so online. If you have any questions or need help, the dedicated Orbitz customer service team is always standing by.

Frequently asked questions

What is the best airport to fly to in Knox County?
Jet into Kirksville Municipal Airport (IRK), the main entry point to Knox County. Booking your flight to this region doesn't get much easier.
How much is a flight to Knox County?
Return fares started as low as $138 this week to Knox County, and reached a high of $218. Some lucky jet-setters journeying out of Chicago (ORD) managed to land one-way tickets starting at just $69.
How to book the cheapest flight to Knox County?
With some of the most exciting flight deals around, a bargain is always waiting for you with Orbitz. The following tips and hints will help you land cheap flights to Knox County — and leave you with more money in your pocket:

  • Depending on where you're departing from, click on the 'Nearby airports' function (located under the departure and arrival form fields). Occasionally, other departure points will have more competitive fares.
  • If your plans aren't written in stone, click on the 'Show flexible dates' link to scan the flight deals across different departure dates. If you find a better fare, book it.
  • You can also use the 'Show options' function to filter results for your preferred carrier, seating class, nonstop flights and refundable flights. Under 'Sort & Filter' to the left, you can even pick the time of day you'd like to fly.
  • Lock in your fare as soon as you've sorted your travel dates. While it does happen from time to time, flights rarely fall in price as your departure date approaches.
  • Bundle your flights, hotels and car rental into an impressive package deal. Save your hard-earned money for things that really excite you, like exploring Knox County.
  • If practical, avoid flying in high seasons. Airfares often hit their highest during school breaks, summer and other vacation periods like Easter, Thanksgiving and Christmas.

What is the best time to book a flight to Knox County?
On average, the cheapest month to book a plane ticket is in January. This is followed by February and August. When seeking a cheap flight to Knox County, it's worth being ready to book. Cheap deals pop up in an instant and don't wait around!
What day of the week is the cheapest to book a flight to Knox County?
Make a booking on a Tuesday, Wednesday or Saturday. Generally, these are the cheapest days of the week to purchase fares to Knox County. The getaway of your dreams starts with an incredible flight deal!
What is the cheapest day of the week to fly to Knox County?
If you're after cheap flights to Knox County, leave early in the week. Orbitz data from 2020 shows Monday is the most affordable day to jet off, followed by Tuesday. Saturday has the most expensive fares, so avoid this day and do your bank account a favor.
What is the cheapest month to fly to Knox County?
Consider traveling in August if you're on a tight budget. Orbitz data has found that it's generally the best month for cheap flights to Knox County. June is when ticket prices are at their highest.
Which airlines allow free cancellation?
Flexibility is important, that's why Orbitz lets you search for airlines that won't penalize you for amendments to your reservation. Enter your departure and arrival points, then select "Filter by flexible change policies." We'll show you options that include free cancellation and no change fees.
What do I need for the flight to Knox County?
Flying doesn't have to be a drag. In fact it can be a joy with a little pre-planning! Make your flight a total breeze with these practical tips:

  • Your travel documents are the most important items you'll need to take on your flight. To avoid any confusion at the time of check-in, make sure that the personal information on your ticket is the same as on your government-issued photo ID.
  • To keep you amused on the short hop to Knox County, download some new music or stock up the audiobook library on your smartphone. Food can also be a good distraction while in the air, so pack some light snacks.
  • Even if you're flying when it's sweltering outside, take a warm top or scarf on board with you. Airplane cabins can get a bit chilly!

How do I get cheap first-class/business deals to Knox County?
Experienced travelers have a way of finding first or business-class flights to Knox County without the sky-high price tag. Be like them with these useful hints:

  • Be flexible with your travel dates and hold out for sales or exclusive offers on first or business-class airfares.
  • A lot of low-cost airlines nowadays offer comfortable business-class seating without the pricey fees.
  • Bid for an upgrade. Some airlines hold online auctions that let you offer a price for a seat up the front. You may also be able to upgrade with points earned through a loyalty scheme.

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.