$45 Car Rentals in Winston-Salem, NC

Reserve your car fast and hassle-free on the free Orbitz app

Free cancellation on most cars, plus option to book now and pay later

Read verified reviews from travelers like you!

Top Car Deals in Winston-Salem

Don't see what you're looking for?

See all car rentals in Winston-Salem
View all cars

Find cheap car rental deals in Winston-Salem, North Carolina

Winston-Salem, so named after a secular city merged with the neighboring missionary settlement, offers an immersive insight into the history of North Carolina. Old Salem recreates missionary life for 18th-century Moravian settlers, while the Reynolda House Museum traces the history of American art on the grounds of an early 20th-century estate.

Explore the historic city in a rental car to take in all of its sights, which are spread out across the sprawling city. Having your own set of wheels also means that you can easily visit other nearby cities to enjoy even more of North Carolina’s culture and cuisine. Use Orbitz to find the perfect rental car for you.

Winston-Salem and beyond: Highlights of the Tar Heel State

Winston-Salem may not be one of the more famous corners of North Carolina, but that just makes its hidden delights even more enchanting to discover. Rent a car to explore the city and the nearby big-name destinations, which we’ve highlighted below.

Old Salem

Winston-Salem prides itself on offering the unexpected. That means discovering wineries in the valleys surrounding the city, or finding Moravian missionaries wearing 18th-century outfits in Old Salem. One of the best reasons to visit this perfectly preserved pocket of history is to try the Moravian sugar cakes, which are still baked in the traditional way.

Journey time: Around five minutes

Distance: Approximately 1.5 miles


The largest city in North Carolina is packed with attractions, from its modern art galleries to its child-friendly museums. It’s also a sporting center in the state – drive here in your rental car to watch the Panthers play football, the Hornets win at basketball, or the Knights hit a home run in baseball.

Journey time: Around 1 hour 30 minutes

Distance: Approximately 80 miles


North Carolina’s capital city packs a formidable punch, and it’s under two hours away from Winston-Salem. Get behind the wheel of your rental car, and head to a city characterized by a charming university campus, an impressive capitol building, and an array of family-friendly attractions. The Museum of Natural Sciences is vast and exhilarating, while Raleigh’s craft beer scene is exploding in popularity.

Journey time: Around 1 hour 45 minutes

Distance: Approximately 100 miles