Hotels in Cairo

Motel 6 Sikeston Mo
Motel 6 Sikeston Mo
110 S Interstate Dr, Sikeston
2.0 out of 5.0
2.7 out of 5 (3 reviews)

Situated in Sikeston, this motel is within 6 mi (10 km) of Sikeston Depot Museum, Boot Heel Golf Club, and Central Park. Hunter-Dawson State Historic Site and ...

$55

$55
Comfort Inn And Suites
Comfort Inn And Suites
109 Matthews Ln, Sikeston
2.5 out of 5.0
4.0 out of 5 (1 reviews)

Situated near the airport, this hotel is within 6 mi (10 km) of Sikeston Depot Museum, Boot Heel Golf Club, and Central Park.

$90

$90
Super 8 - Sikeston/Miner Area
Super 8 - Sikeston/Miner Area
2609 E Malone Ave, Sikeston
2.0 out of 5.0
3.0 out of 5 (13 reviews)

Situated in Sikeston, this hotel is within 3 mi (5 km) of Sikeston Depot Museum, Boot Heel Golf Club, and Central Park. Hunter-Dawson State Historic Site and ...

$51

$51
Quality Inn
Quality Inn
13201 Kessler Road, Cairo
2.0 out of 5.0
4.0 out of 5 (1 reviews)

Situated in Cairo, this hotel is 18.6 mi (30 km) from Ullin City Hall and within 32 mi (52 km) of Columbus-Belmont State Park and Central Park. Sikeston Depot ...

$55

$55
Americas Best Value Inn & Suites Sikeston
Americas Best Value Inn & Suites Sikeston
220 S Interstate Dr, Sikeston
2.0 out of 5.0
3.9 out of 5 (18 reviews)

Located in a rural location, this family-friendly hotel is within 6 mi (10 km) of Sikeston Depot Museum, Central Park, and Boot Heel Golf Club. Cape Splash Family ...

$60

$60
Americas Best Value Inn
Americas Best Value Inn
128 Cheekwood Lane, Ullin
2.0 out of 5.0
3.1 out of 5 (8 reviews)

Situated in a rural location, this motel is 1.7 mi (2.8 km) from Ullin City Hall and within 20 mi (32 km) of Shawnee Community College and Anna City Park. Vienna ...

$70

$70
Quality Inn Charleston
Quality Inn Charleston
102 Drake St, Charleston
2.0 out of 5.0
4.0 out of 5 (2 reviews)

Situated in Charleston, this hotel is within 20 mi (32 km) of Central Park, Fort Defiance, and Sikeston Depot Museum. Boot Heel Golf Club and Hunter-Dawson State ...

$75

$75
Super 8 Charleston MO
Super 8 Charleston MO
310 S Story St, Charleston
2.0 out of 5.0
3.7 out of 5 (10 reviews)

Located in the heart of Charleston, this motel is within 20 mi (32 km) of Fort Defiance, Central Park, and Sikeston Depot Museum. Boot Heel Golf Club and Ullin ...

$55

$55
Eagle Inn Charleston
Eagle Inn Charleston
2811 East Marshall Street, Charleston
2.0 out of 5.0

Situated in a rural location, this motel is within 20 mi (32 km) of Central Park, Sikeston Depot Museum, and Boot Heel Golf Club. Ullin City Hall is 29.3 mi ...

$50

$50
Map
Hotels in Cairo

Magnolia Manor, Mississippi County Hist Soc, Simpatico An Art Gallery Co-Op — with attractions like these, it's no wonder why people visit Cairo. And with 4 hotels to choose from on Orbitz, which are highly rated for Location and Hotel Staff, there's likely a comfortable hotel room available to fit your needs and budget.


Shopping in Cairo

If your headphones break — or if they don't match your outfit — the gadgets at Carter's Mystique are on hand to keep you connected and looking high-tech.


Where to eat in Cairo

Traveling burns a lot of calories, and Cairo offers plenty of places where you can enjoy a quiet meal or break bread with the whole family. The dishes at Las Brisas, Huddle House, Casey's General Store, and Jones Fish and Chicken are good bets for refueling.


Where to stay in Cairo

Cape Girardeau Regional Airport is the main hub for flights into Cairo and the surrounding area.


Outdoor adventures in Cairo

Don't forget to leave time to enjoy a little nature while in Cairo. Head to Diebold Orchards Inc and Delta Connections for a refreshing wak or afternoon picnic.


Best times to visit Cairo

Orbitz offers some great deals all year round, but you can really stretch your travel budget during September, January and February. These months offer respective savings of about 14%, 13% and 9%.


Arts and culture in Cairo

Broaden your horizens during your Cairo trip with a stop in Magnolia Manor and Mississippi County Hist Soc. You can also learn something new or pick up a new work of fiction at Mississippi County Library.


Best times to visit Cairo

Orbitz offers some great deals all year round, but you can really stretch your travel budget during September, January and February. These months offer respective savings of about 14%, 13% and 9%.


Where to stay in Cairo

Cape Girardeau Regional Airport is the main hub for flights into Cairo and the surrounding area.


Shopping in Cairo

If your headphones break — or if they don't match your outfit — the gadgets at Carter's Mystique are on hand to keep you connected and looking high-tech.


* Prices reflect the lowest "base rate" found over the next 30 days. Rates are subject to change and may not include taxes and fees, hotel service charges, extra person charges, or incidentals, such as room service. All rates are displayed in USD unless otherwise noted. Converted rates are provided for your convenience. They are based on today's exchange rate, but the hotel will charge you in the local currency.