Book 2 Star Hotels in Cairo
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Featured Cairo 2 Stars Hotels

Quality Inn Cairo I-57
13201 Kessler Road Cairo IL
Free Cancellation
Reserve now, pay when you stay
2.7 mi from city center
$71 nightly
The price is $79 total per night
$79 total
Jan 17 - Jan 18, 2026
Total with taxes and fees
Quality Inn Cairo I-57 features free WiFi in public areas, coffee in a common area, and free newspapers. If you decide to drive, there's free parking. Front-desk staff are standing by 24/7 to assist with any requests. This hotel also has a picnic area.

Peaceful secluded cabin located near Horseshoe Lake
Miller City IL
10.85 mi from city center
At this cabin, guests have access to barbecue grills.
Kitchen
Pet friendly

Cozy cabins on beautiful Horseshoe Lake
Olive Branch IL
14.88 mi from city center
$133 nightly
The price is $140 total per night
$140 total
Dec 25 - Dec 26
Total with taxes and fees
This cabin is a smoke-free cabin.

The Rested Duck Mallard Room
Olive Branch IL
14.88 mi from city center
$133 nightly
The price is $140 total per night
$140 total
Dec 25 - Dec 26
Total with taxes and fees
This cabin is a smoke-free cabin.

Eagle Inn Charleston
2811 East Marshall Street Charleston MO
Free Cancellation
Reserve now, pay when you stay
9.28 mi from city center
$60 nightly
The price is $67 total per night
$67 total
Dec 25 - Dec 26
Total with taxes and fees
Guests staying at Eagle Inn Charleston enjoy a gym, free WiFi in public areas, and a vending machine. There's free parking if you drive. The 24-hour front desk has staff always at the ready.
Pet friendly
Parking included

Super 8 by Wyndham Charleston/Sikeston East MO
310 S Story St Charleston MO
Free Cancellation
Reserve now, pay when you stay
10.04 mi from city center
$62 nightly
The price is $69 total per night
$69 total
Dec 25 - Dec 26
Total with taxes and fees
At Super 8 by Wyndham Charleston/Sikeston East MO, guests have access to free WiFi in public areas, a business center, and a computer station. A stay here includes free parking. The 24-hour front desk has multilingual staff ready to help with dry cleaning or laundry, and answer any questions about the area. Additional amenities include laundry facilities, a vending machine, and a TV in a common area.

Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout.
Tamms IL
17.4 mi from city center
Guests staying at this vacation home have access to laundry facilities, barbecue grills, and a garden.

Quality Inn Charleston - Sikeston
102 Drake St Charleston MO
11.71 mi from city center
Guests of Quality Inn Charleston - Sikeston enjoy free WiFi in public areas, a business center, and a vending machine. A stay here includes free parking. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations.
Breakfast included
Pet friendly
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Cairo hotels essential information
Accommodation | 25 hotels |
|---|---|
Lowest Price | $67 |
Highest Price | $281 |
Popular hotels | Quality Inn Cairo I-57, Super 8 by Wyndham Charleston/Sikeston East MO, Quality Inn Charleston - Sikeston, Peaceful secluded cabin located near Horseshoe Lake , Cozy cabins on beautiful Horseshoe Lake, Eagle Inn Charleston, The Rested Duck Mallard Room, Beer and s'mores anyone? We've got you! Hunting cabin meets weekend hideout., Charming cottage overlooking Lake Acre |
Recent Reviews

Cozy cabins on beautiful Horseshoe Lake
5/5 Excellent
"The cabin was great"
A verified traveler stayed at Cozy cabins on beautiful Horseshoe Lake
Posted 3 weeks ago



