Hotels in San Diego Santa Fe Depot
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Check prices close to San Diego Santa Fe Depot for tomorrow night, Jul 28 - Jul 29Hotels near San Diego Santa Fe Depot

Handlery Hotel
950 Hotel Cir N, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
3.06 mi from San Diego Santa Fe Depot
$111 nightly
The price is $128 total per night
$128 total
Aug 10 - Aug 11
Total includes taxes and fees
At Handlery Hotel, guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 24 per night. The 24-hour front desk has multilingual staff ready to assist with concierge services, luggage storage, and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and conference space.

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.26 mi from San Diego Santa Fe Depot
$169 nightly
The price is $195 total per night
$195 total
Jul 28 - Jul 29
Total includes taxes and fees
Guests of Wyndham San Diego Bayside have access to an outdoor pool, a gym, and WiFi in public areas. Parking is USD 50.00 per night (USD 60 per night for valet parking)—but if you prefer not to drive, catch a ride in the free airport shuttle at scheduled times. Multilingual staff at the 24-hour front desk can assist with dry cleaning/laundry, securing valuables, and concierge services. Additional amenities include meeting rooms, a conference center, and a business center.
Pool
Free airport shuttle

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.43 mi from San Diego Santa Fe Depot
$244 nightly
The price is $283 total per night
$283 total
Jul 28 - Jul 29
Total includes taxes and fees
Guests staying at Manchester Grand Hyatt San Diego enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is offered for USD 65 per night. Multilingual staff at the 24-hour front desk can assist with luggage storage, tours or tickets, and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and conference space.

The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
5.25 mi from San Diego Santa Fe Depot
$166 nightly
The price is $190 total per night
$190 total
Aug 25 - Aug 26
Total includes taxes and fees
Guests of The Dana on Mission Bay have access to a marina, 2 outdoor pools, and a gym. Self parking is available for USD 35 per night. The front desk has multilingual staff standing by 24 hours a day to assist with luggage storage and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include 2 hot tubs, free WiFi in public areas, and a conference center.

Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.53 mi from San Diego Santa Fe Depot
$272 nightly
The price is $315 total per night
$315 total
Aug 17 - Aug 18
Total includes taxes and fees
Marriott Marquis San Diego Marina features a marina, a full-service spa, and 2 outdoor pools. Valet parking is available for USD 75 per day. The 24-hour front desk has multilingual staff ready to assist with luggage storage, dry cleaning/laundry, and concierge services. Other amenities at this spa hotel include a children's pool, a 24-hour gym, and a sauna.

The Dextro Hotel, BW Premier Collection
1617 1st Avenue, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.54 mi from San Diego Santa Fe Depot
$135 nightly
The price is $157 total per night
$157 total
Aug 3 - Aug 4
Total includes taxes and fees
Guests of Dextro, Little Italy, BW Premier Collection have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 35.00 per day. The front desk has multilingual staff standing by 24 hours a day to assist with luggage storage and tours/tickets. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Free WiFi

Hilton San Diego Bayfront
1 Park Blvd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
1.01 mi from San Diego Santa Fe Depot
$243 nightly
The price is $281 total per night
$281 total
Aug 18 - Aug 19
Total includes taxes and fees
Hilton San Diego Bayfront features a full-service spa, an outdoor pool, and a children's pool. Parking is available for USD 55.00 per night (USD 75.00 per night for valet parking), and there's also limo/town car service. Multilingual staff at the 24-hour front desk can assist with concierge services, luggage storage, and dry cleaning/laundry. Other amenities at this spa hotel include a gym, a sauna, and free WiFi in public areas.

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
3.28 mi from San Diego Santa Fe Depot
$161 nightly
The price is $185 total per night
$185 total
Aug 24 - Aug 25
Total includes taxes and fees
At Best Western Inn & Suites San Diego – Zoo/SeaWorld Area , guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. Self parking is offered for USD 19 per night. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, tours or tickets, and securing valuables. Additional amenities include a hot tub, coffee/tea in a common area, and express check-out.
Pool
Hot Tub

Lafayette Hotel & Club
2223 El Cajon Blvd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
3.14 mi from San Diego Santa Fe Depot
$244 nightly
The price is $280 total per night
$280 total
Jul 28 - Jul 29
Total includes taxes and fees
At Lafayette Hotel & Club, guests have access to an outdoor pool, free WiFi in public areas, and meeting rooms. Valet parking is offered for USD 38 per night. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, concierge services, and luggage storage. Additional amenities include conference space, a porter/bellhop, and a gift shop.
Pool
Pet friendly
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See all available properties in San Diego Santa Fe Depot
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.

Navy Pier
Explore the waterfront in San Diego with a trip to Navy Pier. Stroll along the area's seaside or experience its fascinating museums.

Waterfront Park
After visiting Waterfront Park, make a plan to see the other sights and activities in San Diego. Stroll along the area's waterfront or experience its fascinating museums.
Hotels Great for Sightseeing Near San Diego Santa Fe Depot

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
$169 nightly
The price is $195 total per night from Jul 28 to Jul 29
$195 total
Jul 28 - Jul 29
Total includes taxes and fees
8.2/10 Very Good! (5,791 reviews)

Gaslamp Plaza Suites
520 E St, San Diego, CA
$109 nightly
The price is $124 total per night from Aug 25 to Aug 26
$124 total
Aug 25 - Aug 26
Total includes taxes and fees
8.8/10 Excellent! (1,016 reviews)

Springhill Suites San Diego Downtown/Bayfront
900 Bayfront Court, San Diego, CA
$195 nightly
The price is $225 total per night from Aug 13 to Aug 14
$225 total
Aug 13 - Aug 14
Total includes taxes and fees
9.2/10 Wonderful! (1,017 reviews)
Vacation Rentals Near San Diego Santa Fe Depot

Little Italy Inn - Limited Service Apart Hotel
1736 State St, San Diego, CA
$99 nightly
The price is $113 total per night from Jul 29 to Jul 30
$113 total
Jul 29 - Jul 30
Total includes taxes and fees
8/10 Very Good! (20 reviews)

Kasa Little Italy San Diego
1331 Columbia St, San Diego, CA
$242 nightly
The price is $275 total per night from Jul 29 to Jul 30
$275 total
Jul 29 - Jul 30
Total includes taxes and fees
9.6/10 Exceptional! (256 reviews)

Kasa Gaslamp Quarter San Diego
552 5th Avenue, San Diego, CA
$149 nightly
The price is $169 total per night from Jul 28 to Jul 29
$169 total
Jul 28 - Jul 29
Total includes taxes and fees
8/10 Very Good! (120 reviews)
Historic San Diego Santa Fe Depot Hotels

The Horton Grand, Downtown/Gaslamp Quarter
311 Island Ave, San Diego, CA
$165 nightly
The price is $191 total per night from Jul 28 to Jul 29
$191 total
Jul 28 - Jul 29
Total includes taxes and fees
8.8/10 Excellent! (2,418 reviews)

The Sofia Hotel
150 W Broadway, San Diego, CA
$161 nightly
The price is $186 total per night from Aug 25 to Aug 26
$186 total
Aug 25 - Aug 26
Total includes taxes and fees
8.2/10 Very Good! (1,512 reviews)

Gaslamp Plaza Suites
520 E St, San Diego, CA
$109 nightly
The price is $124 total per night from Aug 25 to Aug 26
$124 total
Aug 25 - Aug 26
Total includes taxes and fees
8.8/10 Excellent! (1,016 reviews)
San Diego Santa Fe Depot hotels essential information
Accommodation | 3,702 hotels |
---|---|
Lowest Price | $113 |
Highest Price | $315 |
Popular hotels | Handlery Hotel, Wyndham San Diego Bayside, Manchester Grand Hyatt San Diego, The Dana on Mission Bay, Marriott Marquis San Diego Marina, The Dextro Hotel, BW Premier Collection, Hilton San Diego Bayfront, Best Western Inn & Suites San Diego – Zoo/SeaWorld Area , Lafayette Hotel & Club |
Recent Reviews

Wyndham San Diego Bayside
5/5 Excellent
"best view ever"
A verified traveler stayed at Wyndham San Diego Bayside
Posted 21 hours ago
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