Hotels in San Diego Santa Fe Depot
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Check prices close to San Diego Santa Fe Depot for tomorrow night, Aug 3 - Aug 4Hotels near San Diego Santa Fe Depot

Handlery Hotel
950 Hotel Cir N, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
3.06 mi from San Diego Santa Fe Depot
$110 nightly
The price is $126 total per night
$126 total
Aug 3 - Aug 4
Total includes taxes and fees
At Handlery Hotel, guests enjoy features like an outdoor pool, a gym, and free WiFi in public areas. Self parking is available for USD 24 per night. The 24-hour front desk has multilingual staff ready to assist with concierge services, luggage storage, and dry cleaning/laundry. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.26 mi from San Diego Santa Fe Depot
$177 nightly
The price is $205 total per night
$205 total
Aug 3 - Aug 4
Total includes taxes and fees
Guests of Wyndham San Diego Bayside have access to an outdoor pool, a gym, and WiFi in public areas. Parking is USD 50.00 per night (USD 60 per night for valet parking)—but if you prefer not to drive, catch a ride in the free airport shuttle at scheduled times. Multilingual staff at the 24-hour front desk can assist with dry cleaning/laundry, securing valuables, and concierge services. Additional amenities include meeting rooms, a conference center, and a business center.
Pool
Free airport shuttle

Embassy Suites by Hilton San Diego Bay Downtown
601 Pacific Hwy, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.33 mi from San Diego Santa Fe Depot
$202 nightly
The price is $234 total per night
$234 total
Aug 17 - Aug 18
Total includes taxes and fees
At Embassy Suites by Hilton San Diego Bay Downtown, guests enjoy an indoor pool, a gym, and WiFi in public areas. Valet parking is available for USD 65 per day, and there's also limo/town car service. Multilingual staff at the front desk are standing by 24/7 to help with securing valuables, concierge services, and dry cleaning/laundry. Other amenities at this family-friendly hotel include meeting rooms, conference space, and a business center.
Pool
Breakfast included

Manchester Grand Hyatt San Diego
1 Market Pl, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.43 mi from San Diego Santa Fe Depot
$236 nightly
The price is $274 total per night
$274 total
Aug 31 - Sep 1
Total includes taxes and fees
Guests staying at Manchester Grand Hyatt San Diego enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Valet parking is offered for USD 65 per night. Multilingual staff at the 24-hour front desk can assist with luggage storage, dry cleaning/laundry, and tours or tickets. Additional amenities include a hot tub, meeting rooms, and conference space.
Pool
Hot Tub

The Dana on Mission Bay
1710 W Mission Bay Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
5.25 mi from San Diego Santa Fe Depot
$184 nightly
The price is $212 total per night
$212 total
Aug 17 - Aug 18
Total includes taxes and fees
Guests of The Dana on Mission Bay have access to a marina, 2 outdoor pools, and a gym. Self parking is available for USD 35 per night. The front desk has multilingual staff standing by 24 hours a day to assist with luggage storage and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Additional amenities include 2 hot tubs, free WiFi in public areas, and a conference center.
Pool
Hot Tub

Hilton San Diego Bayfront
1 Park Blvd, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
1.01 mi from San Diego Santa Fe Depot
$218 nightly
The price is $253 total per night
$253 total
Sep 1 - Sep 2
Total includes taxes and fees
Hilton San Diego Bayfront features a full-service spa, an outdoor pool, and a children's pool. Parking is available for USD 55.00 per night (USD 75.00 per night for valet parking), and there's also limo/town car service. Multilingual staff at the 24-hour front desk can assist with concierge services, luggage storage, and dry cleaning/laundry. Other amenities at this spa hotel include a gym, a sauna, and free WiFi in public areas.
Pool
Hot Tub

Marriott Marquis San Diego Marina
333 W Harbor Dr, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.53 mi from San Diego Santa Fe Depot
$257 nightly
The price is $297 total per night
$297 total
Sep 1 - Sep 2
Total includes taxes and fees
Marriott Marquis San Diego Marina features a marina, a full-service spa, and 2 outdoor pools. Valet parking is available for USD 75 per day. The 24-hour front desk has multilingual staff ready to assist with luggage storage, dry cleaning/laundry, and concierge services. Other amenities at this spa hotel include a children's pool, a 24-hour gym, and a sauna.
Pool
Hot Tub

The Dextro Hotel, BW Premier Collection
1617 1st Avenue, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
0.54 mi from San Diego Santa Fe Depot
$135 nightly
The price is $157 total per night
$157 total
Aug 10 - Aug 11
Total includes taxes and fees
Guests of Dextro, Little Italy, BW Premier Collection have access to an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 35.00 per day. The front desk has multilingual staff standing by 24 hours a day to assist with luggage storage and tours/tickets. Additional amenities include meeting rooms, conference space, and a 24-hour business center.
Pool
Free WiFi

Hampton Inn San Diego/Mission Valley
2151 Hotel Circle South, San Diego, CA
Free Cancellation
Reserve now, pay when you stay
3.05 mi from San Diego Santa Fe Depot
$131 nightly
The price is $151 total per night
$151 total
Aug 4 - Aug 5
Total includes taxes and fees
At Hampton Inn San Diego/Mission Valley, guests enjoy an outdoor pool, a 24-hour gym, and free WiFi in public areas. Self parking is available for USD 26.00 per night. Front-desk staff can answer questions 24/7, and assist with dry cleaning/laundry, tours or tickets, and securing valuables. Additional amenities include conference space, a 24-hour business center, and coffee/tea in a common area.
Pool
Breakfast included
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See all available properties in San Diego Santa Fe Depot
View all propertiesLowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Port of San Diego
Explore the waterfront in San Diego with a trip to Port of San Diego. Wander the seaside and beautiful beaches in the area.

Navy Pier
Explore the waterfront in San Diego with a trip to Navy Pier. Stroll along the area's seaside or experience its fascinating museums.

Waterfront Park
After visiting Waterfront Park, make a plan to see the other sights and activities in San Diego. Stroll along the area's waterfront or experience its fascinating museums.
Hotels Great for Sightseeing Near San Diego Santa Fe Depot

Wyndham San Diego Bayside
1355 N Harbor Drive, San Diego, CA
$177 nightly
The price is $205 total per night from Aug 3 to Aug 4
$205 total
Aug 3 - Aug 4
Total includes taxes and fees
8.2/10 Very Good! (5,776 reviews)

Gaslamp Plaza Suites
520 E St, San Diego, CA
$109 nightly
The price is $124 total per night from Aug 7 to Aug 8
$124 total
Aug 7 - Aug 8
Total includes taxes and fees
8.8/10 Excellent! (1,003 reviews)

Springhill Suites San Diego Downtown/Bayfront
900 Bayfront Court, San Diego, CA
$229 nightly
The price is $265 total per night from Aug 3 to Aug 4
$265 total
Aug 3 - Aug 4
Total includes taxes and fees
9.2/10 Wonderful! (1,000 reviews)
Vacation Rentals Near San Diego Santa Fe Depot

Little Italy Inn - Limited Service Apart Hotel
1736 State St, San Diego, CA
$99 nightly
The price is $113 total per night from Aug 20 to Aug 21
$113 total
Aug 20 - Aug 21
Total includes taxes and fees
7.6/10 Good! (28 reviews)

Kasa Little Italy San Diego
1331 Columbia St, San Diego, CA
$253 nightly
The price is $287 total per night from Aug 3 to Aug 4
$287 total
Aug 3 - Aug 4
Total includes taxes and fees
9.6/10 Exceptional! (260 reviews)

Kasa Gaslamp Quarter San Diego
552 5th Avenue, San Diego, CA
$149 nightly
The price is $169 total per night from Aug 5 to Aug 6
$169 total
Aug 5 - Aug 6
Total includes taxes and fees
8/10 Very Good! (120 reviews)
Historic San Diego Santa Fe Depot Hotels

The Horton Grand, Downtown/Gaslamp Quarter
311 Island Ave, San Diego, CA
$171 nightly
The price is $198 total per night from Aug 25 to Aug 26
$198 total
Aug 25 - Aug 26
Total includes taxes and fees
8.8/10 Excellent! (2,413 reviews)

The Sofia Hotel
150 W Broadway, San Diego, CA
$161 nightly
The price is $186 total per night from Aug 25 to Aug 26
$186 total
Aug 25 - Aug 26
Total includes taxes and fees
8.2/10 Very Good! (1,498 reviews)

Gaslamp Plaza Suites
520 E St, San Diego, CA
$109 nightly
The price is $124 total per night from Aug 7 to Aug 8
$124 total
Aug 7 - Aug 8
Total includes taxes and fees
8.8/10 Excellent! (1,003 reviews)
San Diego Santa Fe Depot hotels essential information
Accommodation | 3,716 hotels |
---|---|
Lowest Price | $113 |
Highest Price | $297 |
Popular hotels | Handlery Hotel, Wyndham San Diego Bayside, Embassy Suites by Hilton San Diego Bay Downtown, Manchester Grand Hyatt San Diego, The Dana on Mission Bay, Hilton San Diego Bayfront, Marriott Marquis San Diego Marina, The Dextro Hotel, BW Premier Collection, Hampton Inn San Diego/Mission Valley |
Recent Reviews

Wyndham San Diego Bayside
5/5 Excellent
"Water pressure was the best I’ve had. "
A verified traveler stayed at Wyndham San Diego Bayside
Posted 8 hours ago
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