Compare Eastern Panama Villas

Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels

Save 10% or more on select hotels with Insider Prices

Book on the app to instantly earn 5% on 350,000+ hotels

Featured Villas in Eastern Panama

Exclusive Villa with panoramic vistas of city and mountains from your own hottub

Exclusive Villa with panoramic vistas of city and mountains from your own hottub

At this villa, guests enjoy features like an outdoor pool, a gym, and a hot tub. Transportation is made easy with limo/town car service. Additional amenities include laundry facilities, local meal delivery service, and barbecue grills.
Pool
Hot Tub
Caribbean Beach House with Pool

Caribbean Beach House with Pool

At this villa, guests have access to an outdoor pool, laundry facilities, and a garden.
Pool
Kitchen
BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

BEACH FRONT HOUSE SURROUNDeD BY 2 PRIVATE BEACHES

Guests staying at this villa have access to laundry facilities, barbecue grills, and a water dispenser. Transportation is made easy with limo/town car service. This beach villa also has a garden.
Kitchen
Washer
Amazing beach villa with access to the carribbean sea

Amazing beach villa with access to the carribbean sea

At this villa, guests have access to barbecue grills.
Kitchen
Pet friendly
Kasa Leilani, the perfect Caribbean gateway!

Kasa Leilani, the perfect Caribbean gateway!

At this villa, guests have access to features like laundry facilities.
Dryer
Pet friendly
Charming 3-bedroom villa with AC and WiFi in soothing Río Hato

Charming 3-bedroom villa with AC and WiFi in soothing Río Hato

At this villa, guests have access to features like laundry facilities. This smoke-free villa also has barbecue grills.
Pool
Kitchen
Don't see what you're looking for?
See all available properties in Eastern Panama
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Eastern Panama

    Ordovician Beach Resort

    Ordovician Beach Resort

    Isla Grande, Isla Grande, Colon
    Private Over the Water Cabin on San Blas Island

    Private Over the Water Cabin on San Blas Island

    9.542876, -78.899058, Narganá, San Blas
    Ranchos de Chalia

    Ranchos de Chalia

    Portobelo via Puerto Lindo, Unit 3, Puerto Lindo, Colón
    $140 nightly
    The price is $153 total per night from Jul 20 to Jul 21
    $153 total
    Jul 20 - Jul 21
    Total includes taxes and fees
    9.6/10 Exceptional! (4 reviews)

Luxury Villas

Book luxury villas in Eastern Panama
There are plenty of ways to up your vacation game, but one of the best is by staying in a luxury villa in Eastern Panama. Villas, with their thoughtful layout and elegant décor, let you travel in style. They come in a variety of sizes and offer a great experience, whether you’re traveling on your own or with a group of friends. Orbitz has fantastic deals on villas in Eastern Panama, so book one now. You’ll feel like a million bucks before you even check in.

Spacious luxury villas in Eastern Panama
You won’t have a problem finding your own space in Eastern Panama. If you’re traveling in a group, go for a three-bedroom or larger villa; separate bedrooms can make it that much easier to keep the peace, especially when you’re all staying in one house. You can also explore Eastern Panama on your own and use a one-bedroom villa as your home base.

A top-end villa experience in Eastern Panama rivals that of a luxury resort. Float in a swimming pool with an elaborate mosaic bottom, work out in your own gym, and let the daily housekeeping staff clean up after you while a private chef whips up one delicious meal after another. This is the life!

Villas in Eastern Panama

Most Popular

More Places To Stay in Eastern Panama