Spa Resorts & Hotels in Mesopotamia
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Featured Mesopotamia Spa Resorts & Hotels

Falls Iguazú Hotel & Spa
Batalla Mbororé S/N, Lote 05 Puerto Iguazú Misiones
$260 nightly
The price is $266 total per night
$266 total
Jan 10 - Jan 11, 2026
At Falls Iguazú Hotel & Spa, guests enjoy a full-service spa, an outdoor pool, and a children's pool. Free valet and self parking are available, or if you're not driving, take the airport shuttle (available 24 hours) for USD 50 per vehicle one-way. The front desk has multilingual staff on hand 24/7 to help with concierge services, luggage storage, and securing valuables. Other amenities at this luxury hotel include a gym, a steam room, and free WiFi in public areas.
Pool
Hot Tub

Gran Melia Iguazú
Parque Nacional Iguazu Puerto Iguazú Misiones
Free Cancellation
Reserve now, pay when you stay
$716 nightly
The price is $722 total per night
$722 total
Dec 19 - Dec 20
Guests of Gran Melia Iguazú have access to a full-service spa, 2 outdoor pools, and a children's pool. If you drive, take advantage of free parking. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, tours or tickets, and securing valuables. Other amenities at this luxury hotel include a gym, a sauna, and a rooftop terrace.
Pool
Breakfast included

Mercure Iguazu Hotel Iru
Selva Iryapu S N - Predio 600 Has Puerto Iguazú Misiones
$186 nightly
The price is $190 total per night
$190 total
Jan 5 - Jan 6, 2026
Mercure Iguazu Hotel Iru features a full-service spa, an outdoor pool, and a 24-hour gym. You can take advantage of free parking, along with an airport shuttle (available 24 hours) for USD 22 per vehicle one-way. The 24-hour front desk has staff standing by to help with luggage storage, concierge services, and dry cleaning/laundry. If you like to take your furry friend along on your adventures, this pet-friendly property offers food and water bowls. Other amenities at this luxury hotel include a sauna, free WiFi in public areas, and a hot tub.
Pool
Hot Tub

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls
Rodovia Br 469 Km 32 Foz do Iguaçu PR
$829 nightly
The price is $867 total per night
$867 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Hotel das Cataratas, A Belmond Hotel, Iguassu Falls enjoy a full-service spa, an outdoor pool, and a children's pool. Airport transportation is made easy with an airport shuttle (available 24 hours) for BRL 480 per vehicle roundtrip. Multilingual staff at the front desk are standing by 24/7 to help with dry cleaning/laundry, tours or tickets, and securing valuables. Other amenities at this luxury hotel include a gym, a steam room, and free WiFi in public areas.
Pool
Breakfast included

Sanma Hotel
Rodovia das Cataratas Km 21 Foz do Iguaçu PR
$194 nightly
The price is $203 total per night
$203 total
Jan 3 - Jan 4, 2026
Total with taxes and fees
Sanma Hotel features a full-service spa, an outdoor pool, and a children's pool. There's free parking if you drive. The front desk has multilingual staff on hand 24/7 to help with luggage storage, concierge services, and dry cleaning/laundry. Other amenities at this luxury hotel include a gym, a sauna, and free WiFi in public areas.
Pool
Hot Tub

Panoramic Grand
Av. Córdoba y Félix de Azara Puerto Iguazú Misiones
At Panoramic Grand, guests enjoy a full-service spa, an outdoor pool, and a children's pool. You can put free parking to good use if you drive. The front desk has multilingual staff on hand 24/7 to help with tours or tickets, securing valuables, and luggage storage. Other amenities at this spa hotel include a gym, a sauna, and a rooftop terrace.
Pool
Breakfast included

Loi Suites Iguazú Hotel
Selva Iriapu Sin Numero Puerto Iguazú Misiones
$326 nightly
The price is $332 total per night
$332 total
Jan 10 - Jan 11, 2026
Guests of Loi Suites Iguazú Hotel have access to a full-service spa, 2 outdoor pools, and a gym. You can take advantage of free parking, along with an airport shuttle (available 24 hours) for USD 40 per vehicle one-way. The front desk has multilingual staff on hand 24/7 to help with luggage storage, concierge services, and securing valuables. Other amenities at this luxury resort include a sauna, free WiFi in public areas, and conference space.
Pool
Breakfast included

Iguazu Grand Resort Spa & Casino
Route 12 Km 1640 Puerto Iguazú Misiones
Free Cancellation
Reserve now, pay when you stay
$336 nightly
The price is $342 total per night
$342 total
Dec 19 - Dec 20
Iguazu Grand Resort Spa & Casino features a full-service spa, 3 outdoor pools, and a casino. Free valet and self parking are available, or if you're not driving, take the airport shuttle (available 24 hours) for USD 20 per vehicle one-way. The front desk has multilingual staff on hand 24/7 to help with luggage storage, dry cleaning/laundry, and concierge services. Other amenities at this luxury hotel include a nightclub, karaoke, and an indoor pool.
Pool
Breakfast included

Hotel Saint George
Avenida Cordoba 148 Puerto Iguazú Misiones
Free Cancellation
Reserve now, pay when you stay
$129 nightly
The price is $133 total per night
$133 total
Dec 19 - Dec 20
At Hotel Saint George, guests enjoy a full-service spa, an outdoor pool, and a children's pool. You'll find limited parking. The 24-hour front desk has staff standing by to help with luggage storage, concierge services, and securing valuables. Other amenities at this spa hotel include a gym, free WiFi in public areas, and a hot tub.
Pool
Hot Tub

Exe Hotel Cataratas
Ruta Nacional 12 km 4 Puerto Iguazú Misiones
Free Cancellation
Reserve now, pay when you stay
$89 nightly
The price is $95 total per night
$95 total
Jan 16 - Jan 17, 2026
Guests staying at Exe Hotel Cataratas enjoy an indoor pool, an outdoor pool, and free WiFi in public areas. You can put free parking to good use if you drive. The 24-hour front desk has multilingual staff ready to assist with concierge services, luggage storage, and securing valuables. Other amenities at this luxury hotel include free newspapers, laundry facilities, and a gift shop.
Pool
Breakfast included

Boutique Hotel Delafonte
1 De Mayo Y Corrientes Puerto Iguazú Misiones
Guests staying at Boutique Hotel Delafonte enjoy access to a winery, an outdoor pool, and free WiFi in public areas. There's free offsite parking, and a shuttle from the hotel to the airport (available 24 hours) for USD 25 per vehicle. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry, luggage storage, and securing valuables. Additional amenities include a hot tub, coffee/tea in a common area, and a terrace.
Pool
Hot Tub

Amérian Portal del Iguazú Hotel
Avenida 3 Fronteras 780 Puerto Iguazú Misiones
Free Cancellation
Reserve now, pay when you stay
$136 nightly
The price is $140 total per night
$140 total
Dec 26 - Dec 27
Guests of Amérian Portal del Iguazú Hotel have access to a full-service spa, a water park, and an indoor pool. Free valet and self parking are available, and there's also an area shuttle. The 24-hour front desk has multilingual staff ready to assist with dry cleaning/laundry, luggage storage, and tours or tickets. Other amenities at this spa resort include an outdoor pool, a children's pool, and a gym.
Pool
Hot Tub

Akwati Suites Iguazu
Hipolito Yrigoyen and Tareferos Puerto Iguazú Misiones Province
Akwati Suites Iguazu offers an outdoor pool, free WiFi in public areas, and a hot tub. Free parking is available if you drive. The front desk is staffed 24 hours a day to help with securing valuables and tours/tickets. Additional amenities include laundry facilities and a garden.
Pool
Hot Tub

Amérian Hotel Casino Gala
Juan Domingo Perón 330 esq. Necochea Resistencia Chaco
Free Cancellation
Reserve now, pay when you stay
Guests staying at Amérian Hotel Casino Gala enjoy access to a casino, an outdoor pool, and free WiFi in public areas. Front-desk staff can answer questions 24/7, and assist with securing valuables, luggage storage, and tours or tickets. Additional amenities include a reception hall and a porter/bellhop.
Pool
Breakfast included

Carnaval Hotel Casino
Av. Irrazabal, 750 Encarnacion
Free Cancellation
Reserve now, pay when you stay
$77 nightly
The price is $84 total per night
$84 total
Dec 21 - Dec 22
Total with taxes and fees
Guests of Carnaval Hotel Casino have access to a full-service spa, a casino, and an indoor pool. Free parking is available if you drive. Front-desk staff can answer questions 24/7, and assist with luggage storage, securing valuables, and tours or tickets. Other amenities at this spa hotel include an outdoor pool, a gym, and a sauna.
Pool
Hot Tub
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Mesopotamia hotels essential information
Accommodation | 491 hotels |
|---|---|
Lowest Price | $84 |
Highest Price | $867 |
Popular hotels | Falls Iguazú Hotel & Spa, Gran Melia Iguazú, Mercure Iguazu Hotel Iru, Hotel das Cataratas, A Belmond Hotel, Iguassu Falls, Sanma Hotel , Panoramic Grand, Loi Suites Iguazú Hotel, Iguazu Grand Resort Spa & Casino, Hotel Saint George, Exe Hotel Cataratas, Boutique Hotel Delafonte, Amérian Portal del Iguazú Hotel, Akwati Suites Iguazu, Amérian Hotel Casino Gala, Carnaval Hotel Casino |
Recent Spa Resorts & Hotels Reviews

Hathor Concordia
5/5 Excellent
"The hotel staff is very polite Service: "Friendly and efficient," "helpful," "attentive," "welcoming smile," "professional"."
A verified traveler from Luquillo stayed at Hathor Concordia
Posted 13 days ago


