Book 2 Star Hotels in New Madrid
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Featured New Madrid 2 Stars Hotels

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid MO
0.42 mi from city center
$343 nightly
The price is $369 total per night
$369 total
Jul 4 - Jul 5
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has a garden.

New Orleans Inn Portageville
600 US-61 Portageville MO
Free Cancellation
Reserve now, pay when you stay
14.24 mi from city center
$52 nightly
The price is $56 total per night
$56 total
Jul 5 - Jul 6
Total with taxes and fees
At New Orleans Inn Portageville , guests have access to a garden. There's free parking if you drive. Front-desk staff are standing by 24/7 to assist with any requests.

Reelfoot Lake Inn
1520 State Route 21 East Tiptonville TN
15.29 mi from city center
$61 nightly
The price is $70 total per night
$70 total
Jul 31 - Aug 1
Total with taxes and fees
Guests staying at Reelfoot Lake Inn enjoy free WiFi in public areas, laundry facilities, and barbecue grills. Front-desk staff are standing by 24/7 to assist with any requests.

3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters
Hornbeak TN
16.9 mi from city center
$343 nightly
The price is $384 total per night
$384 total
Jul 5 - Jul 6
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has barbecue grills.

For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier.
Hornbeak TN
17.53 mi from city center
$429 nightly
The price is $481 total per night
$481 total
Jul 5 - Jul 6
Total with taxes and fees
At this lodge, guests have access to features like laundry facilities. This family-friendly lodge also has barbecue grills.

Duck Hunting, Fishing or Relaxing Family Vacation
Hornbeak TN
17.55 mi from city center
Guests staying at this vacation home have access to laundry facilities, barbecue grills, and a garden.

Fairfield Inn & Suites by Marriott Sikeston
1239 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
18.86 mi from city center
$110 nightly
The price is $124 total per night
$124 total
Jul 12 - Jul 13
Total with taxes and fees
Built in 2025, the brand new Fairfield Inn & Suites by Marriott Sikeston offers an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The 24-hour front desk has staff standing by to help with luggage storage, dry cleaning/laundry, and securing valuables. Additional amenities include coffee/tea in a common area and laundry facilities.

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Free Cancellation
Reserve now, pay when you stay
18.87 mi from city center
$102 nightly
The price is $115 total per night
$115 total
Jul 19 - Jul 20
Total with taxes and fees
At Hampton Inn Sikeston, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. You can take advantage of free parking if you drive. The front desk is staffed 24 hours a day to help with securing valuables and luggage storage. If you like to take your furry friend along on your adventures, this pet-friendly property offers an off-leash area. Additional amenities include meeting rooms, conference space, and a 24-hour business center.

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Free Cancellation
19.01 mi from city center
$105 nightly
The price is $119 total per night
$119 total
Aug 2 - Aug 3
Total with taxes and fees
Guests staying at Holiday Inn Express & Suites Sikeston Southwest by IHG enjoy an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The 24-hour front desk has staff standing by to help with luggage storage and securing valuables. Additional amenities include a business center, coffee/tea in a common area, and a meeting room.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
New Madrid hotels essential information
Accommodation | 59 hotels |
|---|---|
Lowest Price | $56 |
Highest Price | $481 |
Popular hotels | Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!, Hampton Inn Sikeston, Holiday Inn Express & Suites Sikeston Southwest by IHG, Fairfield Inn & Suites by Marriott Sikeston, New Orleans Inn Portageville , Reelfoot Lake Inn, 3 bedroom house on Reelfoot Lake, perfect for families, fisherman and hunters, Duck Hunting, Fishing or Relaxing Family Vacation, For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier. |
Recent Reviews

Hampton Inn Sikeston
5/5 Excellent
"Rooms were clean and comfortable. Breakfast was ok. Staff was friendly and helpful. Pool area was a bit steamy, but granddaughter enjoyed it very much. We will definitely recommend."
A verified traveler stayed at Hampton Inn Sikeston
Posted 7 hours ago


