Hotels in Santee
Search over 62 hotels from $110
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Top Rated Santee Hotels

Lewis and Clark Resort
43496 Shore Drive Yankton SD
16.75 mi from city center
$104 nightly
The price is $110 total per night
$110 total
May 12 - May 13
Total with taxes and fees
Guests of Lewis and Clark Resort enjoy features like a marina, free WiFi in public areas, and a conference center. If you drive, put free parking to good use. Front-desk staff can help with luggage storage, and provide local restaurant recommendations. Other amenities at this beach hotel include a seasonal outdoor pool, coffee/tea in a common area, and a computer station.
Pool
Pet friendly

Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!
Crofton NE
16.86 mi from city center
$856 nightly
The price is $946 total per night
$946 total
May 12 - May 13
Total with taxes and fees
At this vacation home, guests have access to features like laundry facilities. This smoke-free vacation home also has a garden.
Kitchen
Washer

Spacious Lakeview Cabin Minutes from Private Beach
Crofton NE
15.27 mi from city center
At this cabin, guests have access to features like laundry facilities. This smoke-free cabin also has barbecue grills.
Kitchen
Washer

Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake
Crofton NE
15.29 mi from city center
This cabin is a smoke-free cabin.
Pet friendly
Air conditioning

Beautiful log cabin, only 1.7 miles from lake dock by Lewis & Clark, Yankton SD
Yankton SD
14.13 mi from city center
At this cabin, guests have access to features like laundry facilities. This family-friendly cabin also has barbecue grills.
Kitchen
Washer

Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!
Yankton SD
17.31 mi from city center
$833 nightly
The price is $875 total per night
$875 total
May 12 - May 13
Total with taxes and fees
Guests staying at this vacation home enjoy a gym, an arcade/game room, and laundry facilities. Transportation is made easy with limo/town car service. Friendly staff can provide concierge services, and also offer advice about sightseeing. Other amenities at this family-friendly vacation home include local meal delivery service, a garden, and barbecue grills.
Kitchen
Washer

Gavins Point Lakehouse
Yankton SD
14.95 mi from city center
At this vacation home, guests have access to an arcade/game room, laundry facilities, and a garden.
Kitchen
Washer

ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18
Yankton SD
17.22 mi from city center
$703 nightly
The price is $738 total per night
$738 total
May 13 - May 14
Total with taxes and fees
Guests of this vacation home enjoy a hot tub, laundry facilities, and local meal delivery service. Transportation is made easy with limo/town car service. Friendly staff can provide concierge services, and also offer advice about sightseeing. Other amenities at this family-friendly vacation home include barbecue grills and a garden.
Hot Tub
Kitchen

Haven by the Lake
Yankton SD
16.97 mi from city center
Guests staying at this vacation home have access to laundry facilities, a garden, and barbecue grills.
Kitchen
Washer

Hunters & outdoor lovers charming 4-bedrm lake house with best view on the lake!
Crofton NE
9.67 mi from city center
At this cabin, guests have access to features like laundry facilities. This smoke-free cabin also has a garden.
Kitchen
Washer
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where is a good place to stay in Santee?
What are some of the best hotels in Santee?
Consider this top hotel in Santee:
- Lewis and Clark Resort is located 16.8 mi away, and this hotel has a marina, free WiFi, and free parking.
Santee hotels essential information
Accommodation | 62 hotels |
|---|---|
Lowest Price | $110 |
Highest Price | $946 |
Popular hotels | Lewis and Clark Resort, Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!, Spacious Lakeview Cabin Minutes from Private Beach, Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake, Beautiful log cabin, only 1.7 miles from lake dock by Lewis & Clark, Yankton SD, Leather&Spruce - Luxury Lake area fun funky home with amenities. Great for 2-18!, Gavins Point Lakehouse, ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18, Haven by the Lake, Hunters & outdoor lovers charming 4-bedrm lake house with best view on the lake!, Lewis & Clark Trail Hideaway, SD side / 2 min to the lake / 10 min to Yankton. , HotTub, PingPong, Firepit, 2 LivingRooms just .67 mi to beach |
Recent Reviews

Lewis and Clark Resort
5/5 Excellent
"We stayed in a three bedroom cabin for two nights May 9-10 so it was not busy season yet. The grounds were mowed and in good repair. The exterior and interior of the cabins are showing their age but everything worked and was fine for us. We cooked a full breakfast every morning and enjoyed long walks along the lake. Glad we stayed here over a traditional hotel. I would stay again. "
A verified traveler stayed at Lewis and Clark Resort
Posted 1 day ago
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