Hotels in Santee

Search over 66 hotels from $114

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Top Rated Santee Hotels

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Santee hotels essential information

Accommodation
66 hotels
Lowest Price
$114
Highest Price
$1,127
Popular hotels
Lewis and Clark Resort, Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!, Spacious Lakeview Cabin Minutes from Private Beach, Cozy cabin near Lewis and Clark Lake and CJ’s at the Lake, Charming Lake House within Walking Distance from Lake, Newly Remodeled Creekside Bungalow on 3 acres with Private Beach Beside Creek, ThePinecone - luxury vacation rental awesome deck with view & amenities for 2-18, Beautiful newly renovated home overlooking Lewis and Clark lake. , Lewis and Clark Lake Home/Loft for Rent/Lake View Property and Lake Access, Fully furnished lake house with cozy spaces, full kitchen, and lake views., Lewis & Clark Trail Hideaway, SD side / 2 min to the lake / 10 min to Yankton. , Haven by the Lake

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