Ecuador may have travel restrictions in place, including self-quarantine, due to COVID-19.

Find out moreOpens in new tab or window

Book Santa Isabel Vacations

Save up to ^ on your trip when booking flight + hotel together

Santa Isabel Travel Guide

Let the team at Orbitz find amazing hotel and flight deals for you. If you want to organize that unforgettable Santa Isabel trip, it's just a few clicks away! If you combine your bookings, you'll save up to $369^! Just take your pick of hotels, rental cars, airfares and experiences. With 500 partner airlines and more than 500,000 hotels globally, you have the freedom to pick where you want to stay and who you'll fly with! Our package deals will help you create the getaway of your dreams. With endless options to combine all your travel needs, the only thing left to do is pack your bags.

Where is Santa Isabel?

You know you want to vacation there and what you'd love to see, but do you know just where Santa Isabel is? Read on to find out. 210 miles to the north of Santa Isabel is Quito. Zaruma is another nearby destination, just 30 miles to the south.

Places to Visit in Santa Isabel

Wonder at how the unique geological formations of Carachulla came to be. Need some more ideas? Refreshing air and green surroundings are found in abundance at Santa Isabel Central Park.

Car Rentals in Santa Isabel

Santa Isabel beckons, and the best way to explore it is from the driver's seat. Search, compare and book car rentals in Santa Isabel in a matter of clicks through Orbitz. Ready to roll?

Nearest Airports to Santa Isabel

Going to fly into Mariscal Lamar Airport (CUE)? You'll be discovering the best of Santa Isabel in no time! It's located 35 miles northeast of Santa Isabel's center.

Popular Places to Visit Near Santa Isabel

Explored all of Santa Isabel already? Don't worry! Gualaceo is just 50 miles away and has plenty of activities to keep you busy. If you want to spend the whole day in the area, stop by Gualaceo Market in the morning. Then head on over to Gualaceo Church and the Ecuagenera Orchids. Searching for more options? El Tambo is 55 miles from Santa Isabel. Visit for attractions like Ingapirca Ruins, Canar Central Park and Honorato Vasquez Park. You've got a world of choice!

No Cancellation Fees

Breathe easy knowing that whatever the motivation behind altering or canceling your booking, we won't slap on a fee.^ Why not call your selected airline and hotel and ask if they have similar policies?


Top things to do in Santa Isabel

More trip options