Business Hotels in Muscatine, IA
Earn Orbucks instantly: $1 Orbuck = $1 USD, good toward hotels
Save 10% or more on select hotels with Insider Prices
Book on the app to instantly earn 5% on 350,000+ hotels
Featured Muscatine Business Hotels

AmericInn by Wyndham Muscatine
3115 Hwy 61 North Muscatine IA
Free Cancellation
Reserve now, pay when you stay
$84 nightly
The price is $94 total per night
$94 total
Apr 2 - Apr 3
Total with taxes and fees
At AmericInn by Wyndham Muscatine, guests have access to an indoor pool, free WiFi in public areas, and a hot tub. If you drive, take advantage of free parking. The 24-hour front desk has staff standing by to help with dry cleaning or laundry, and answer any questions about the accommodations. Additional amenities include conference space, a business center, and laundry facilities.

Comfort Inn Muscatine near Hwy 61
115 Cleveland St Muscatine IA
Free Cancellation
$77 nightly
The price is $86 total per night
$86 total
Apr 25 - Apr 26
Total with taxes and fees
Comfort Inn Muscatine near Hwy 61 features an indoor pool, free WiFi in public areas, and coffee in a common area. If you drive, put free parking to good use. The 24-hour front desk has staff standing by to help secure valuables, and answer any questions about the accommodations. Additional amenities include free newspapers, laundry facilities, and a vending machine.

Best Western Muscatine / Pearl City Hotel
305 Cleveland St Muscatine IA
Free Cancellation
Reserve now, pay when you stay
$94 nightly
The price is $105 total per night
$105 total
Mar 29 - Mar 30
Total with taxes and fees
At Best Western Muscatine / Pearl City Hotel, guests enjoy features like an indoor pool, a gym, and free WiFi in public areas. A stay here includes free parking. The front desk is staffed 24/7 to help with luggage storage, and answer any questions about the accommodations. Additional amenities include a business center, a microwave in a common area, and express check-out.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Muscatine hotels essential information
Accommodation | 308 hotels |
|---|---|
Lowest Price | $86 |
Highest Price | $105 |
Popular hotels | AmericInn by Wyndham Muscatine, Comfort Inn Muscatine near Hwy 61, Best Western Muscatine / Pearl City Hotel |
Recent Business Hotels Reviews

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
5/5 Excellent
"The building was very clean and was nicely decorated/furnished. Staff were friendly. I don't wish to add a negative, but the advertised "heated pool" was actually "cold." It was a bummer, as my husband and I were celebrating our 23rd anniv. and haven't been swimming in ages. I mentioned it to the desk host; she said it's kept at a steady 85 degrees but that she would mention it to the maintenance department. The hotel is lovely overall. (Except the pool - well it's actually an inviting, clean pool -- just way too cold.)"
A verified traveler stayed at The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
Posted 2 days ago


