$376 Midsize Car Rental in Colorado

For as little as $376, in Colorado, you can drive away in a rental car booked through Orbitz. We find the wheels you need for less.

Have a look at our incredible offers or simply enter your trip details for instant access to more Midsize rentals in Colorado, all from leading suppliers. Sure, price varies by location, but you can filter your search by customer rating and car rental company to find exactly what you want.

Yes. Orbitz offers free cancellation on many bookings to give you peace of mind if you need to cancel or change your reservation. You can also book now and pay later in a wide variety of deals.

Orbitz makes it easy to compare prices and customer ratings on Midsize cars in just a few clicks. Make the most of our hassle-free cancellation policy and our Price Guarantee—if you find the Midsize rental cheaper elsewhere within 24 hours, we’ll refund you the difference.

Colorado has several rental locations with great Midsize cars to choose from. Check out the list of destinations further down the page. They’re conveniently located in the main cities, near airports, and in popular Colorado spots.