This vacation home places you next to Ohio River Valley and within a few miles (5 km) of other popular attractions like KFC Yum Center. The vacation home includes a kitchen, a fireplace, and a balcony.
~ Deaconess Guesthouse — Historic Elegance on the Ohio River, Minutes from Louisville & Jeffersonville ~
★ Where History Meets Modern Luxury: Step into timeless sophistication at Deaconess Guesthouse, a masterfully reimagined 1800s landmark that once served as Jeffersonville’s first public hospital. Painstakingly restored by Charming Vacation Homes, this distinguished estate blends rich history with refined, boutique-style living. Overlooking the serene Ohio River and just minutes from downtown Louisville, the Bourbon Trail, and Jeffersonville’s lively riverfront district, it offers an experience that is both captivating and unforgettable.
★ Designed for Connection & Celebration: With 8 beautifully appointed bedrooms and 6 spa-inspired bathrooms across four private suites, the estate accommodates up to 24 guests in absolute comfort. Perfect for family reunions, executive retreats, weddings, and milestone celebrations, the home’s thoughtful layout provides an ideal balance of gathering spaces and peaceful privacy. Every corner—from the grand living areas to the artfully curated décor—has been designed to inspire conversation, laughter, and lasting memories.
★ Signature Amenities & Exclusive Touches: 1. Private Hot Tub & Fire Pit – Relax under the stars in your own riverfront sanctuary 2. Wraparound Porches & Scenic Balconies – Begin your day with sunrise coffee, end with sunset cocktails 3. Stargazing Dome Experience – A whimsical retreat for dreamers of all ages 4. Ample On-Site Parking – Effortless access for large groups, luxury vehicles, and VIP transport
★ The Perfect Location: - Walk to Downtown Jeffersonville – Boutique shopping, acclaimed dining, and vibrant riverfront entertainment - 2.5 Miles to Downtown Louisville – Discover bourbon distilleries, Churchill Downs, world-class museums, and live music - Adventure Awaits – Kayaking, biking trails, waterfront festivals, and outdoor concerts just steps away
★ Your Private Riverfront Retreat: From tranquil mornings on the porch to fireside evenings beneath the stars, Deaconess Guesthouse invites you to slow down, reconnect, and indulge in life’s finer moments. Its historic legacy, stunning river views, and luxury amenities create an experience that transcends the ordinary—a stay where every detail tells a story.
Reserve your stay today and experience Jeffersonville’s most iconic riverfront estate—where history, luxury, and unforgettable memories meet.
★ CONVENIENT LOCATION The house is centrally located and is within a 10-15 minute Uber/Lyft drive to most locations:
- Big Four Walking Bridge (Connecting KY and IN) - 0.4 miles (2 mins) - Downtown Louisville/ 4th Street Live - 2.4 miles (6 mins) - Churchill Downs (DERBY) - 7.7 miles (15 mins) - KFC Yum Center - 2.3 miles (7 mins) - Waterfront Park - 3.4 miles (9 mins) - Papa Johns Stadium (Cardinal Stadium) - 6.4 miles (11 mins) - University of Louisville - 6.5 miles (12 mins) - Kentucky Fairgrounds - 6.5 miles (10 min) - Kentucky Exposition Center - 6.7 miles (11 mins) - Kentucky Kingdom - 7.4 miles (13 mins) - Louisville Airport - 8.6 miles (10 mins) - Highland Festival Grounds - 8.5 miles (12 mins) - Louisville Mega Cavern - 10.2 miles (19 mins) - Ford LAP Plant - 10.9 miles (16 mins) - UPS Worldport - 11.2 miles (20 mins) - Waverly Hills Sanatorium - 17 miles (30 mins) - Valhalla Golf Club - 19 miles (27 mins)
PROPERTY HIGHLIGHTS ★ Exclusive Riverfront Retreat near Downtown Louisville/Jeffersonville: Experience an extraordinary blend of historic elegance and modern sophistication at this rare architectural masterpiece—ideally located just minutes from Louisville, Jeffersonville, New Albany and Clarksville. ★ Prime Ohio Riverfront Setting: Wake up to breathtaking panoramic views of the Ohio River and stroll to Jeffersonville’s vibrant downtown, filled with boutique shopping, fine dining, live entertainment and local festivals. ★ Historic Charm Meets Modern Luxury: This meticulously restored landmark showcases timeless craftsmanship, curated interiors and designer finishes—creating an atmosphere that’s both refined and deeply inviting. ★ Scenic Views & Inviting Spaces: Enjoy your morning coffee or evening wine on covered porches and private balconies overlooking the river’s shimmering waters—perfect for unwinding and taking in the view. ★ Designed for Comfort & Connection: With 8 elegant bedrooms and 6 spa-inspired bathrooms, this home is designed for both relaxation and togetherness, offering open, light-filled spaces ideal for family and friends. ★ Chef-Inspired Living: Featuring four gourmet kitchens with premium appliances and upscale touches, this home provides the perfect canvas for culinary experiences and memorable gatherings. ★ Family & Pet Friendly: From cozy reading nooks to kid-friendly zones and pet accommodations, every detail is thoughtfully designed so everyone—two-legged or four—feels perfectly at home. ★ Private Outdoor Oasis: Unwind in the hot tub, gather by the fire pit, relax under the Hyperdome or gazebo and enjoy outdoor dining and lawn games under the starlit sky. ★ Entertainment for Every Occasion: Stay entertained with Smart Roku TVs in every bedroom, indoor and outdoor games and multiple lounge spaces that make every stay as fun as it is relaxing. ★ Perfect for Groups & Celebrations: Ideal for family reunions, retreats, and extended stays, the property offers 4 washer/dryer sets, parking for 8 and flexible gathering spaces designed to bring people together. ★ Your Riverfront Escape Awaits: Discover the ultimate fusion of history, luxury, and location—a one-of-a-kind getaway where every moment feels like a celebration on the banks of the Ohio River.
★ TOP 2025 UPCOMING EVENTS -Jack O’ Lantern Spectacular: Oct 2025 -Halloween Weekends Louisville South KOA Holiday: Oct 2025
★ OTHER 2025 UPCOMING EVENTS (Including TRADE SHOWS) -Equipment Expo: Oct 21th to 24th, 2025 -North American International Livestock Exposition: Nov 6th to 20th, 2025
NOTE: 1) Must be 25 or older to book. 2) Please review house rules before booking. Rental Agreement & Security Hold: Guests must e-sign our rental agreement and Must submit a $500 off-platform security hold that will be collected upon signing rental agreement but it will not be placed until 2 days prior to arrival and released 7 days after departure, if no damages are reported. Please note we are API Connected to a hotel-style software called OwnerRez to safely and securely take off-platform security deposits. 3) ** STRICT CANCELLATION for DERBY/ Bourbon & Beyond ** 4) Visitors are not permitted unless you make a special request to the host and receive approval. 5) We have exterior surveillance with voice and recording capabilities of the parking area and front door. They are in place for security of guests and the home. We do NOT have interior cameras nor camera in the backyard. 6) The Dome is not recommended for use during hot summer months. We suggest enjoying the other amenities during warmer months for optimal comfort. 7) We cannot accommodate early check-ins or late check-outs for same-day turnarounds. 8) For days without same-day turnarounds, we offer early check-ins and late check-outs at the following rates: $100 for up to 2 hours, $250 for 2 to 4 hours, and a full day's rate for more than 4 hours. 9) Please note that for cancellations of bookings made on platforms other than Airbnb, a Stripe card processing fee of 3% will be deducted from the total refund.
PLEASE REVIEW THE HOUSE RULES BEFORE BOOKING. THANK YOU!
The vacation home is air-conditioned and features a kitchen, 6 bathrooms, and a balcony, and there's space to spread out with 8 bedrooms. Guests can enjoy a Smart TV and stay connected with free WiFi. Other standard amenities include a washing machine, a fireplace, and a sofa bed.
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If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Area rugs in public areas
Handrails in hallways
Handrails in stairways
Hardwood flooring in public areas
Smooth flooring in public areas
Thin carpet in public areas
Tile flooring in public areas
Well-lit path to entrance
Smoking not allowed
Services and conveniences
Iron/ironing board
Location highlights
In the city center
Near a hospital
Near a zoo
Near the marina
On a river
On the waterfront
Things to do
Arcade/game room
Water park
Casino nearby
Fishing nearby
Golfing nearby
Kayaking nearby
Motor boating nearby
Theme park nearby
Winery tours nearby
Safety features
Carbon monoxide detector (host has indicated there is a carbon monoxide detector on the property)
Smoke detector (host has indicated there is a smoke detector on the property)
First aid kit
Fire extinguisher
Deadbolt lock
General
At least 80% lighting from LEDs
Garden
Recycling
Unit size: 5,800 square feet
Water-efficient showers
Water-efficient toilets
Policies
Check-in
Check-in time starts at 4:00 PM
Contactless check-in available
Minimum check-in age: 25
Check-out
Check-out before 10:00 AM
Special check-in instructions
You will receive an email from the host with check-in and check-out instructions
Rules
Must sign rental agreement upon booking which will be sent via email
A $500 security hold will be placed 2 days prior to arrival and released 7 days after departure, if no damages are reported
Must follow all house rules listed in the end of the description and also on the rental agreement.
Pets
This property welcomes pets
Service animals exempt from fees
Note from host: Up to 2 pets 50lbs max.
Children and extra beds
Children allowed: ages 0-17
Events
No events allowed
Smoking
Smoking is not permitted
Important information
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card, or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
Onsite parties or group events are strictly prohibited
Host has indicated there is a carbon monoxide detector on the property
Host has indicated there is a smoke detector on the property
Safety features at this property include a fire extinguisher, a first aid kit, and a deadbolt lock
This property is managed through our partner, Vrbo. You will receive an email from Vrbo with a link to a Vrbo account, where you can change or cancel your reservation
Check-in: 4:00 PM
Check-out: 10:00 AM
Minimum check-in age: 25
We should mention
Details about charges, deposits, or other important information:
This property is managed by a professional host. The provision of housing is linked to their trade, business, or profession.
Charges for extra guests may apply and vary depending on the property's policy.
A cash deposit, credit card, or debit card for incidental charges, as well as a government-issued photo ID, may be required at check-in.
Special requests are subject to availability at the time of check-in and can't be guaranteed. Certain requests may come with additional charges.
Onsite parties or group events are strictly prohibited.
Onsite safety features include a carbon monoxide detector, a fire extinguisher, a smoke detector, a first aid kit, and a deadbolt lock.
Property is also known as
orp5b65a95x
Frequently asked questions
What's there to see close to this vacation home?
Located steps from Ohio River Valley, this vacation home is in Jeffersonville, and within a 10-minute walk of Ohio River and Big Four Bridge. You'll also find KFC Yum Center and Whiskey Row within a short drive.
Is parking available on site at this vacation home?
No, this vacation home doesn't offer parking.
Is this vacation home adjacent to a casino?
No, this vacation home is not connected to a casino.
Will I find an indoor pool at this vacation home?
No, this vacation home doesn't have an indoor pool; however, there is a hot tub.
Is 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities good for couples?
Amenities that appeal to couples at this riverfront vacation home include a fireplace, a kitchen, and a smart TV.
Are there hot tubs at 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities?
Yes, guests can enjoy a spa tub at this vacation home.
Does this vacation home include breakfast service?
No, this vacation home doesn't offer breakfast.
Will this vacation home allow pets to stay for free?
Although pets can't stay for free, they are welcome at this vacation home.
Are there connecting rooms at this vacation home?
No, there aren't connecting rooms at this vacation home.
Where is the closest airport to this vacation home?
The closest major airport to this vacation home is Louisville, KY (LOU-Bowman Field), which is 9.3 mi away (16 minutes by car). Another top airport is Louisville Intl. Airport (SDF), which is located 9.2 mi away (15-minute drive).
Are there rooms with balconies at 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities?
Yes, every accommodation at 6000SF~Sleeps24~Louisville~Views~LawnOasis~HotTub~Dome~Firepit~Pet~Lux Amenities comes with a balcony with some featuring water views.