Greenville Vacation Packages

You'll love every second you spend in thrilling Greenville. The skilled team at Orbitz can help you get your vacation underway by bundling top-value flights and hotels. Do you want to save up to $374? All you have to do is combine your bookings by choosing your desired hotels, airfares, rental cars and experiences. And that's not all — you've got lots of flexibility. Mix and match from 500 airlines and more than 500,000 worldwide accommodation options. Our package deals will help you design the trip you've been dreaming about. With endless options to bundle all your travel requirements, all that's left to do is pack your bags!

Where is Greenville?

Your annual leave's been approved, work mates have spoken highly of Greenville and you just need a little reminder of where it actually sits on the map? Sit back and we'll guide you there. This destination is approximately 95 miles northwest of the capital of South Carolina, Columbia. Greenville is also 7 miles northwest of Mauldin. Enjoy meeting the locals on vacation? This part of Greenville - Spartanburg is home to around 58,000 residents.

Car Rentals in Greenville

Take your love of travel to new heights by checking out car rentals in Greenville. It doesn't matter where you go or what you hope to do, Orbitz will help you find a rental that fits your adventurous spirit. Go straight from the runway to the highway when you pick up your car at Greenville-Spartanburg International Airport. Make your way to Alamo Rent A Car and Budget. They are located just a short stroll away. Hertz and Avis are also nearby. Staying int he downtown area? Start your drive on a high by beginning your journey from the center of the action. You'll find Enterprise situated at 501 Buncombe St.

Where to stay in Greenville – Hotel Accommodation

Orbitz can help you get the best possible deal! Currently, there are 37 hotels in Greenville. Select the facilities and amenities to suit your traveling needs. The Courtyard by Marriott Greenville Downtown and Hampton Inn & Suites Greenville Downtown RiverPlace are a few fabulous lodging options in this area.

Nearest Airports to Greenville

Fasten your seatbelt! You'll soon be approaching Greenville-Spartanburg International Airport (GSP), the best airport for Greenville. The terminal lies 11 miles east of the downtown area and may be the beginning point of your amazing vacation.

Popular Places to Visit Near Greenville

Duncan is a favorite of tourists. It's situated 16 miles from Greenville, and you won't have to look far to find things to do. Begin delving into the story of the region at the BMW Performance Center. If you're eager to find out more, check out the Hollywild Animal Park and the River Falls Golf Course too. After more options? Lyman is 16 miles from Greenville. Make your way to this destination for attractions like the Village Greens Golf Club, Shipwreck Cove and Century Park. You've got all the choice in the world!

No Cancellation Fees

You can be sure that whatever the reason for canceling or altering your booking, we won't hit you with a fee.^ Why not touch base with your chosen airline and hotel to check if they do the same?

Top Greenville vacation package deals

Price found within the past 48 hours. Click for updated prices.

3.5-star property

Hilton Greenville

8.2/10 Very Good! (1,018 reviews)

Jan 9 - Jan 11

2 night stay

Tampa (TPA) to Greenville (GSP)

Breeze Airways • Coach

Greenville (GSP) to Tampa (TPA)

Southwest Airlines • Coach

$269

per person

just found

This is our go-to hotel for all events at Clemson! Amazing hotel with the greatest staff!

Reviewed on Aug 22, 2025

3.0-star property

Holiday Inn Greenville - Woodruff Road by IHG

8.6/10 Excellent! (653 reviews)

Dec 3 - Dec 6

3 night stay

Tampa (TPA) to Greenville (GSP)

Southwest Airlines • Non-stop roundtrip • Coach

$322

per person

found 3 hours ago

Clean new hotel, friendly staff. The bathroom was nice and spacious. The beds were comfortable. Breakfast was made to order, priced well. Downtown Greenville is about 15 minutes drive but there are a lot of restaurants near by the hotel. Also Trader Joe’s and Wholefoods are really close.

Reviewed on May 10, 2022

4.0-star property

Park Place Apartments by Landing

7.8/10 Good! (40 reviews)

Dec 3 - Dec 6

3 night stay

Tampa (TPA) to Greenville (GSP)

Southwest Airlines • Non-stop roundtrip • Coach

$389

per person

found 3 hours ago

Loved the apartment! Very spacious, clean, brand new. Access to bike paths. Seemed like a quirky location but everything is close by car or bike.

Reviewed on Sep 6, 2025

2.5-star property

Best Western Plus Greenville I-385 Inn & Suites

9.2/10 Wonderful! (1,376 reviews)

Dec 3 - Dec 6

3 night stay

Tampa (TPA) to Greenville (GSP)

Southwest Airlines • Non-stop roundtrip • Coach

$347

per person

found 3 hours ago

Quick stay overnight. Room clean and quiet. Satisfied with the experience. Thank you

Reviewed on Jul 15, 2025

4.0-star property

Hotel Hartness

9.8/10 Exceptional! (601 reviews)

Jan 9 - Jan 11

2 night stay

Tampa (TPA) to Greenville (GSP)

Breeze Airways • Coach

Greenville (GSP) to Tampa (TPA)

Southwest Airlines • Coach

$351

per person

just found

First of all, LOVE the staff. We get drinks regularly at the hotel bar and the staff is amazing. We decided to stay in the hotel for a special occasion even though we have been loyal local customers since the restaurant and hotel opened. Overall, the experience was ok. The rooms are like a typical Hyatt or Hilton- nothing special. Our biggest issue was with breakfast. It was also ok, but sparse. Waiting for another batch of eggs to be cooked is understandable, but not having the pastries or cups restocked shows a lack of desire when the employee is standing there on her phone. And there must have been 7 employees standing around and snacking on the breakfast items around the time it closed, which is very bad optics. Our biggest issues was that the coffee was moved to the bar after breakfast but the creamer was spoiled. It appeared that it had not been refrigerated and was actually curdled; chunks came into our coffee cups. I think that Hotel Hartness needs to lean less on the architecture and surroundings and more on the little things that make a hotel experience something that is above average.

Reviewed on Mar 18, 2025