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Orbitz makes it easy to find the best Edisto Island Serpentarium hotel deals for your trip. With an outstanding selection, easy-to-use search tools and descriptive hotel profiles, you'll find Edisto Island Serpentarium hotel deals in a wink..
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Popular hotels | The Edisto Escape 5 Min Drive From Beach - 3bdrm, sleeper, NEW Queen Beds!, Private Deepwater Dock; 180 Degree Coastline Views; Angler's Paradise; TV, Gorgeous Oceanfront 6 bdrm, 6 ba. home, heated swim spa, elevator, private!, Moonrise Point: Amazing Ocean Views w/ Private Dock;Minutes to Beach; Dogs Welcome, Creekside Home in Gated Community with Ocean/Marsh Views, The Gulls Nest Beach House, Beachfront, Dog-Friendly House w/Patio, Free WiFi, Private W/D, AC, Dog-Friendly Home Right On Beach w/ Private Washer/Dryer & Free WiFi, Adorable island cottage with marsh views, screened porch, firepit, grill, & W/D |