Eastern Panama Vacation Homes

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Featured Vacation Homes in Eastern Panama

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Eastern Panama

    Ordovician Beach Resort

    Ordovician Beach Resort

    Isla Grande Isla Grande Colon
    10/10 Exceptional! (3 reviews)
    HOTEL ISLA GRANDE

    HOTEL ISLA GRANDE

    Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province
    $88 nightly
    The price is $98 total per night from Dec 16 to Dec 17
    $98 total
    Dec 16 - Dec 17
    Total with taxes and fees
    5/10 (4 reviews)
    Ranchos de Chalia

    Ranchos de Chalia

    Portobelo via Puerto Lindo, Unit 3 Puerto Lindo Colón
    $110 nightly
    The price is $122 total per night from Dec 21 to Dec 22
    $122 total
    Dec 21 - Dec 22
    Total with taxes and fees
    9.6/10 Exceptional! (11 reviews)

Eastern Panama Vacation Homes

Book vacation homes in Eastern Panama
Next time you take a group getaway top Eastern Panama, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Eastern Panama vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Eastern Panama vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Eastern Panama; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Eastern Panama rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Eastern Panama is sure to be a winner.

Eastern Panama Vacation Homes essential information

Accommodation
35 Vacation Homes
Lowest Price
$69
Highest Price
$170
Popular accommodation
Spacious Beach House on the ocean front with huge pool and patio., Tudor Mountain Retreat, Cabaña La Punta op het Strand!!, Jacuzy, pool and lake at the same house., Casa Frente al Mar - Isla Grande, Caribbean Paradise - Beachfront Getaway, Nice house in Portobelo, Skybluebyguanche , Cara al mar Cacique, A fantastic place between the sea and the jungle