Eastern Panama Vacation Homes

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Featured Vacation Homes in Eastern Panama

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotel Options in Eastern Panama

    Ranchos de Chalia

    Ranchos de Chalia

    Portobelo via Puerto Lindo, Unit 3, Puerto Lindo, Colón
    $117 nightly
    The price is $129 total per night from Oct 31 to Nov 1
    $129 total
    Oct 31 - Nov 1
    Total with taxes and fees
    9.6/10 Exceptional! (5 reviews)
    Ordovician Beach Resort

    Ordovician Beach Resort

    Isla Grande, Isla Grande, Colon
    10/10 Exceptional! (3 reviews)
    HOTEL ISLA GRANDE

    HOTEL ISLA GRANDE

    Final de paseo La Punta Isla Grande, 01, Isla Grande, Colón Province
    $105 nightly
    The price is $115 total per night from Oct 30 to Oct 31
    $115 total
    Oct 30 - Oct 31
    Total with taxes and fees
    4/10 (2 reviews)

Eastern Panama Vacation Homes

Book vacation homes in Eastern Panama
Next time you take a group getaway top Eastern Panama, don’t confine your friends and family to one or two hotel rooms. Instead, snag a deal on a full-sized house and get the best of both worlds. Vacation home rentals are perfect for families and large groups that want to live like locals on vacation. Whether you are searching for a villa that pulls out all the stops or a four-bedroom house to host the best summer vacation ever, Orbitz has a variety of Eastern Panama vacation homes for rent that are ideal for you. Your perfect pad is only a few clicks away.

Homes for every Eastern Panama vacation
If you’re planning a vacation with a lot of people, you’ll want room to stretch out, and a rental home has plenty of space. Many vacation homes also come with everything you’ll need for a proper getaway, like kitchens with every gadget you can think of, along with updated furnishings, fancy spa tubs and balconies. You may even wind up in a rental home that has a sprawling backyard for barbecues, games and general relaxation. These rentals offer the added bonus of putting you right in the thick of things in Eastern Panama; instead of going to a small hotel room at the end of a busy day, you’re going home.

Vacations are all about creating lasting memories, and a Eastern Panama rental home makes it easy to create good ones. Whether you’re getting the college crowd back together or bringing along your folks and your kids, a trip to Eastern Panama is sure to be a winner.

Eastern Panama Vacation Homes essential information

Accommodation
36 Vacation Homes
Lowest Price
$110
Highest Price
$488
Popular accommodation
Tudor Mountain Retreat, Spacious Beach House on the ocean front with huge pool and patio., Jacuzy, pool and lake at the same house., Cabaña La Punta op het Strand!!, Nice house in Portobelo, Skybluebyguanche , Caribbean Paradise - Beachfront Getaway, Casa Anzuelo is an oceanfront home that is all about the water and nature., Cara al mar Cacique, A fantastic place between the sea and the jungle