
$99 Cheap flights to O'Higgins Region
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Cheap flights to O'Higgins Region from $99 One Way, $194 Round Trip
$194 return flights and $99 one-way flights to O'Higgins Region were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Deals For This Weekend's Flights
Origin | Destination | Travel Dates | Flights From* |
---|---|---|---|
GRU | Santiago | September 28 to October 4 | $211 |
EZE | Santiago | September 28 to October 5 | $226 |
MIA | Santiago | September 26 to October 9 | $519 |
YYZ | Santiago | September 28 to October 13 | $599 |
LAX | Santiago | September 27 to October 8 | $610 |
JFK | Santiago | September 26 to October 1 | $859 |
LGA | Santiago | September 26 to October 1 | $891 |
MAD | Santiago | September 26 to November 5 | $1,023 |
Find The Perfect Hotel For After Your Flight
Our Top O'Higgins Region Apartment Hotels

Cabañas Lo de Mariana

Cabañas Rokar
Reviewed on Feb 16, 2017

Cabañas San Andres

Cabañas Tierra de Osos
Score Epic O'Higgins Region Accommodation Deals

Santa Cruz Plaza
Reviewed on Sep 7, 2025

Hotel Terrado Rancagua
Reviewed on Jul 11, 2025

Vik Chile
Reviewed on Feb 22, 2025

Noi Blend Colchagua
Reviewed on Apr 21, 2025
Family Friendly Hotels in O'Higgins Region

Hotel Boutique Solaz Bella Vista de Colchagua
Reviewed on Apr 20, 2025

Hotel Boutique Vendimia Premium
Reviewed on Oct 5, 2024

Santa Cruz Plaza
Families like: Outdoor pool, kids club, babysitting, bicycle rentals
Reviewed on Sep 7, 2025

Cabañas San Andres
Need a Car For After Your Flight?
Economy

Compact

Midsize

SUV

O'Higgins Region
Snag some “suite” deals when you add cheap hotel rooms to O'Higgins Region flights at Orbitz. You can score tickets to ballgames, concerts and other activities while planning your low fare flights. For non-stop air tickets or planned layovers, Orbitz is your discount travel resource.
Budget Prices, Luxury Life
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Fun for All
While shopping Orbitz sales on O'Higgins Region flights, remember to throw in some fun. Ticket sales for music, theatre, sports and more can be found on the Activities page. Just tell us what you want to do, and Orbitz will save your seat.
Non-Stop or Stop and Visit
Will you be flying round-trip or one-way? Going directly from Point A to Point B? Maybe you’d like to have dinner with family and friends along the way. Whether you need non-stop flights to {destination.name} or lowest cost layovers on O'Higgins Region flights, you will always find the best air travel prices at Orbitz.
All in One
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Frequently asked questions
City Destinations in O'Higgins Region
Airlines Operating
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.