COVID-19 alert: Travel requirements are changing rapidly, including need for pre-travel COVID-19 testing and quarantine on arrival.

Book Cape Girardeau Vacations

Save up to ^ on your trip when booking flight + hotel together

Cape Girardeau Travel Guide

You'll relish every second in wonderful Cape Girardeau. The switched-on team at Orbitz will help you kickstart your adventure by linking up the best airfares and hotels. Combining your bookings is one of the simplest ways to save money. Choose your preferred airfares, hotels, rental cars and experiences to save as much as $369^! And more good news — if you have no clue where to stay or who to fly with, our comprehensive database has more than 500,000 international accommodation options and 500 partner airlines. The choice is completely yours! When it comes to creating the trip you've been dreaming about, you have limitless options with Orbitz.

Where is Cape Girardeau?

So, you've been told Cape Girardeau is a top place to visit? Can't for the life of you remember where it is? Allow us to help. You'll find it approximately 170 miles southeast of Jefferson City, the state capital of Missouri, and about 8 miles south of Jackson. This area of Missouri is home to some 38,000 people.

Places to Visit in Cape Girardeau

Forget about mundane family vacations. Grab your swimsuit and towel and plan a visit to Cape Splash Family Aquatic Center, where the water is cool and the fun never stops. Seeking more options? Cape Girardeau Conservation Nature Center is the perfect place for nature buffs of all ages to learn all about the natural environment of this region.

Car Rentals in Cape Girardeau

Adventure is the fuel of life, and there’s no better way to find it than with the freedom of your own ride. See and do more by checking out car rentals in Cape Girardeau with Orbitz. Unfortunately, there are no car rental companies around Cape Girardeau Municipal Airport, so you'll have to make other plans if you're arriving by air. If you enjoy ease and convenience, check out Enterprise.

Where to stay in Cape Girardeau – Hotel Accommodation

With just 10 hotels in Cape Girardeau, you should get in quick! Orbitz has everything you need to lock in a decent room. We'll make organizing your getaway easy and straightforward. Top hotels are the Drury Inn & Suites Cape Girardeau and Pear Tree Inn Cape Girardeau West.

Nearest Airports to Cape Girardeau

If you're flying in to Cape Girardeau, you'll likely be touching down at Cape Girardeau Municipal Airport (CGI). Grab a coffee and get your bearings after climbing out of the plane. This is the nearest airport, sitting 7 miles away from the center of town.

Popular Places to Visit Near Cape Girardeau

If you've got a spare day and you're happy to travel 20 miles, check out Anna. This nearby area is brimming with things to see and do. Anna City Park is a fantastic place to start understanding the culture of the area. The Lincoln Heritage Winery and the StarView Vineyards shouldn't be missed either. If this isn't your style, try Cobden. Just 25 miles away, this area is home to other noteworthy attractions such as the Rustle Hill Winery, the Owl Creek Vineyard and Giant City State Park. Spend a day or two here to visit them all!

No Cancellation Fees

Canceling or making changes to a booking can often be quite tedious — but not with us! We don't ask for a fee, which makes it simple.^ Airlines and hotels sometimes have a similar policy, so it's a wise idea to contact them.

Top rated hotels for your Cape Girardeau vacation

Don't see what you're looking for?
See all available properties in Cape Girardeau
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.