
Antofagasta Region Vacation Packages
Book a Stay + Flight or Car to save on your trip
Top places to visit in Antofagasta Region
Antofagasta Region Vacation Package Deals
One-stop vacation shopping with Orbitz will give you direct access to Antofagasta Region packages from $221, but the real beauty of a package vacation is that Orbitz does all the searching for you.
Gone are the days of hunting for a flight and hotel separately, comparing hundreds of flight sales and hotel deals, with the added pressure of keeping track of all those pesky reference numbers. Check out an all-inclusive resort hotel package, where the price will also cover your food, drink, and activities, or a simple flight and hotel package, and enjoy the luxury of having all your essential information in one place.
Whether you’re planning on visiting Antofagasta Region in peak season () or you want to avoid the crowds and go during the quieter months (), you can customize your package to your own unique travel needs.
Don’t forget to join Orbitz Rewards and start earning Orbucks to spend on bookings for over 350,000 hotels across the world. For each dollar you spend, you instantly earn 1 Orbuck, which you can redeem at your convenience. Being an Orbitz Reward member also means you get access to exclusive deals with Insider Prices as well as VIP Hotel benefits and upgrades.
When you book a package deal with Orbitz, not only are you in for a quick and easy booking process, but you also get the chance to make some great savings. And since the flight and hotel are paid for upfront and in one place, managing your budget will be a breeze.
Top Antofagasta Region vacation package deals


Hotel Agua del Desierto
Sep 22 - Sep 25
Santiago (SCL) to Calama (CJC)
Reviewed on Feb 11, 2020


Pat'ta Hoiri Hotel
Sep 20 - Sep 24
Santiago (SCL) to Calama (CJC)
Calama (CJC) to Santiago (SCL)

Hotel Modular Express Calama
Sep 22 - Sep 25
Santiago (SCL) to Calama (CJC)
Reviewed on Jul 6, 2025
Top rated hotels for your Antofagasta Region vacation package

Diego de Almagro San Pedro de Atacama

Hotel La Casa de Don Tomas

Sami Atacama Lodge
Things to do

Small-Group Tour to Tatio Geysers Machuca Village & Rio Putana wetlands

Full-Day Excursion to the El Tatio Geysers















