Cheap flights from MDT to ROA (Harrisburg Intl. to Roanoke Regional)
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Cheap Flights from MDT to ROA starting at $304 One Way, Round Trip
Prices starting at for return flights and $304 for one-way flights to Roanoke Regional were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Hotel Ideas near Roanoke Regional
Airport Hotels near Roanoke Regional
Spark by Hilton Roanoke Airport
3695 Thirlane Rd Nw Roanoke VA
$65 nightly
The price is $73 total per night from Apr 26 to Apr 27
$73 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and a free airport shuttle. Popular attractions Valley View Mall and ...
8.8/10 Excellent! (344 reviews)
There is not a lot of parking, so plan accordingly. We were lucky enough to get the last spot when we got there after going to a bar late at night. The door is a really hard close even on the accessible room my friend stayed in. The amenities were great, you can tell the building is very new! Most ...
Reviewed on Apr 14, 2026
Hyatt Place Roanoke Airport/Valley View Mall
5040 Valley View Blvd North Roanoke VA
$101 nightly
The price is $114 total per night from Apr 26 to Apr 27
$114 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,015 reviews)
Great staff, easy check in/out. Room is always in great condition, up to date, and clean. Breakfast is very good with options and freshness. Great place to stay, also very convenient to the airport for early flights.
Reviewed on Apr 15, 2026
Country Inn & Suites by Radisson, Roanoke, VA
7860 Plantation Rd Roanoke VA
$101 nightly
The price is $114 total per night from May 6 to May 7
$114 total
May 6 - May 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,175 reviews)
Very friendly staff, clean property and decent breakfast
Reviewed on Apr 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels In Roanoke
Country Inn & Suites by Radisson, Roanoke, VA
7860 Plantation Rd Roanoke VA
$101 nightly
The price is $114 total per night from May 6 to May 7
$114 total
May 6 - May 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,175 reviews)
Very friendly staff, clean property and decent breakfast
Reviewed on Apr 14, 2026
The Liberty Trust
101 S Jefferson St, Roanoke VA 24011 Roanoke VA
$157 nightly
The price is $178 total per night from Apr 19 to Apr 20
$178 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this luxury hotel in Roanoke. Enjoy free WiFi, breakfast (surcharge), and a 24-hour front desk. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,313 reviews)
The hotel is located next to a very popular bar. We stayed there on a Friday and Saturday night in April and our entire family was awake from midnight until 2:30am as the bar outside was too loud. Do not stay at this hotel, we were on the 4th floor and couldn't sleep for hours. Absolute ...
Reviewed on Apr 12, 2026
Hotel Roanoke & Conference Ctr, Curio Collection by Hilton
110 Shenandoah Ave Ne Roanoke VA
$188 nightly
The price is $213 total per night from Apr 30 to May 1
$213 total
Apr 30 - May 1
Total with taxes and fees
Book a stay at this luxury hotel in Roanoke. Enjoy free WiFi, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the property condition ...
9.4/10 Exceptional! (1,000 reviews)
Everything was perfect, surprised by the $20 parking.
Reviewed on Apr 14, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Roanoke Hotels With Airport Transportation
Quality Inn Roanoke Airport
6626 Thirlane Rd Roanoke VA
$80 nightly
The price is $90 total per night from Apr 19 to Apr 20
$90 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
7.2/10 Good! (1,000 reviews)
Very dated!
Reviewed on Mar 31, 2026
Spark by Hilton Roanoke Airport
3695 Thirlane Rd Nw Roanoke VA
$65 nightly
The price is $73 total per night from Apr 26 to Apr 27
$73 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and a free airport shuttle. Popular attractions Valley View Mall and ...
8.8/10 Excellent! (344 reviews)
There is not a lot of parking, so plan accordingly. We were lucky enough to get the last spot when we got there after going to a bar late at night. The door is a really hard close even on the accessible room my friend stayed in. The amenities were great, you can tell the building is very new! Most ...
Reviewed on Apr 14, 2026
Baymont by Wyndham Salem Roanoke Area
179 Sheraton Drive Salem VA
$67 nightly
The price is $76 total per night from Apr 19 to Apr 20
$76 total
Apr 19 - Apr 20
Total with taxes and fees
Book a stay at this business-friendly motel in Salem. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
7.4/10 Good! (393 reviews)
Breakfast selections were great. Pet friendly and friendly staff
Reviewed on Apr 15, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Low Priced Roanoke Hotels
Travelodge by Wyndham Roanoke
6621 Thirlane Rd Roanoke VA
$51 nightly
The price is $57 total per night from Apr 22 to Apr 23
$57 total
Apr 22 - Apr 23
Total with taxes and fees
Stay at this hotel in Roanoke. Enjoy free WiFi, free parking, and an outdoor pool. Popular attractions Splash Valley at Green Ridge Recreation Center and AMF ...
5.8/10 (999 reviews)
The room was dirty first of all. No trash can at all. Wifi cuts in and out, dirt all over the walls, holes found beer cans behind bed, smelled awful with having a non smoking room the green cover blankets covered in burn holes, i booked one night online and made another booking before 11 this morning ...
Reviewed on Mar 28, 2026
Howard Johnson Hotel & Conference Center by Wyndham Salem
1671 Skyview Rd Salem VA
Book a stay at this business-friendly hotel in Salem. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Green Hill Park Trailhead and Hanging ...
6/10 (1,000 reviews)
No breakfast
Reviewed on Apr 8, 2026
Spark by Hilton Daleville Roanoke North
446 Roanoke Rd Daleville VA
$81 nightly
The price is $91 total per night from Apr 22 to Apr 23
$91 total
Apr 22 - Apr 23
Total with taxes and fees
Book a stay at this business-friendly hotel in Daleville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.2/10 Very Good! (1,005 reviews)
Great experience, friendly staff and clean property
Reviewed on Apr 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Family Friendly Hotels in Roanoke
Country Inn & Suites by Radisson, Roanoke, VA
7860 Plantation Rd Roanoke VA
$101 nightly
The price is $114 total per night from May 6 to May 7
$114 total
May 6 - May 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,175 reviews)
Very friendly staff, clean property and decent breakfast
Reviewed on Apr 14, 2026
Hyatt Place Roanoke Airport/Valley View Mall
5040 Valley View Blvd North Roanoke VA
$101 nightly
The price is $114 total per night from Apr 26 to Apr 27
$114 total
Apr 26 - Apr 27
Total with taxes and fees
Book a stay at this business-friendly hotel in Roanoke. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
8.6/10 Excellent! (1,015 reviews)
Great staff, easy check in/out. Room is always in great condition, up to date, and clean. Breakfast is very good with options and freshness. Great place to stay, also very convenient to the airport for early flights.
Reviewed on Apr 15, 2026
MARCH DISCOUNT DAYS BOOK NOW BERNARDS LANDING-BEST AMENITIES INDOOR POOL HOTTUB
Moneta VA
Stay at this condo in Moneta. Enjoy free WiFi, a fitness center, and laundry facilities. Popular attractions Smith Mountain Lake and Pelican Point Yacht Club ...
9.4/10 Exceptional! (162 reviews)
Excellent condo for a weekend getaway. Was quiet and very clean. Close to lots of stores, restaurants, activities. Property owner was very helpful & quick to respond. Will stay again.
Reviewed on Apr 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
MDT to ROA Route Info
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MDT Address & GPS
Address:
One Terminal Drive
Middletown PA, 17057
United States
IATA Code:
MDT
Longitude:
-76.756057
Latitude:
40.196008
Time Zone:
America/New_York
ROA Address & GPS
Address:
5202 Aviation Drive, N.W.
Roanoke VA, 24012-1148
United States
IATA Code:
ROA
Longitude:
-79.970384
Latitude:
37.320509
Time Zone:
America/New_York
Other Flights from Harrisburg Intl. Airport (MDT)
- Capital City Airport (HAR)
- Lancaster Airport (LNS)
- Penn Valley Airport (SEG)
- Reading Regional Airport (RDG)
- Hagerstown Regional Airport (HGR)
- Martin State Airport (MTN)
- Baltimore Washington Intl. Thurgood Marshall Airport (BWI)
- Williamsport Regional Airport (IPT)
- University Park Airport (SCE)
- Montgomery County Airpark Airport (GAI)
Frequently asked questions
Map To Nearby Hotels
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.