Cheap flights from DSM to MFR (Des Moines Intl. to Rogue Valley Intl.)

Earn rewards on top of your airline miles with Orbitz Rewards

Many airlines offer flexible change policies

Sign up to receive text alerts about your trip

Cheap Flights from DSM to MFR starting at $353 One Way, $480 Round Trip

Prices starting at $480 for return flights and $353 for one-way flights to Rogue Valley Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Sat, Aug 1 - Sat, Aug 8
DSM
Des Moines
MFR
Medford
$480 Roundtrip, found 1 day ago
$480
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Sat, Aug 1 from Des Moines to Medford, returning Sat, Aug 8, priced at $480 found 1 day ago
Wed, Aug 19 - Tue, Sep 1
DSM
Des Moines
MFR
Medford
$482 Roundtrip, found 1 day ago
$482
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Wed, Aug 19 from Des Moines to Medford, returning Tue, Sep 1, priced at $482 found 1 day ago
Sat, Feb 14 - Tue, Feb 24
DSM
Des Moines
MFR
Medford
$485 Roundtrip, found 5 days ago
$485
Roundtrip
found 5 days ago
Select Alaska Airlines flight, departing Sat, Feb 14 from Des Moines to Medford, returning Tue, Feb 24, priced at $485 found 5 days ago
Mon, Apr 27 - Mon, May 4
DSM
Des Moines
MFR
Medford
$497 Roundtrip, found 6 days ago
$497
Roundtrip
found 6 days ago
Select Alaska Airlines flight, departing Mon, Apr 27 from Des Moines to Medford, returning Mon, May 4, priced at $497 found 6 days ago
Sat, Aug 1 - Sat, Aug 8
DSM
Des Moines
MFR
Medford
$510 Roundtrip, found 1 day ago
$510
Roundtrip
found 1 day ago
Select Alaska Airlines flight, departing Sat, Aug 1 from Des Moines to Medford, returning Sat, Aug 8, priced at $510 found 1 day ago

Hotel Ideas near Rogue Valley Intl.

Airport Hotels near Rogue Valley Intl.

Rogue Regency Inn and Suites

Rogue Regency Inn and Suites

3 out of 5
2300 Biddle Rd Medford OR
$85 nightly
The price is $95 total per night from Jan 28 to Jan 29
$95 total
Jan 28 - Jan 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Medford. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,793 reviews)
staff good. room good but old. no complaints and would stay again.

Reviewed on Jan 22, 2026

Rogue Regency Inn and Suites
My Place Hotel-Medford OR

My Place Hotel-Medford OR

3 out of 5
580 Airport Rd Medford OR
$88 nightly
The price is $99 total per night from Feb 20 to Feb 21
$99 total
Feb 20 - Feb 21
Total with taxes and fees
Book a stay at this business-friendly hotel in Medford. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the ...
9/10 Wonderful! (1,542 reviews)
Nice clean rooms close to the airport

Reviewed on Jan 25, 2026

My Place Hotel-Medford OR
Springhill Suites By Marriott Medford Airport

Springhill Suites By Marriott Medford Airport

3 out of 5
3519 HEATHROW WAY Medford OR
$110 nightly
The price is $124 total per night from Feb 6 to Feb 7
$124 total
Feb 6 - Feb 7
Total with taxes and fees
Book a stay at this business-friendly hotel in Medford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,034 reviews)
Clean and quite....and great staff!

Reviewed on Jan 14, 2026

Springhill Suites By Marriott Medford Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Medford

Rogue Regency Inn and Suites

Rogue Regency Inn and Suites

3 out of 5
2300 Biddle Rd Medford OR
$85 nightly
The price is $95 total per night from Jan 28 to Jan 29
$95 total
Jan 28 - Jan 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Medford. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,793 reviews)
staff good. room good but old. no complaints and would stay again.

Reviewed on Jan 22, 2026

Rogue Regency Inn and Suites
Compass by Margaritaville in Medford

Compass by Margaritaville in Medford

4 out of 5
2399 S Pacific Hwy Medford OR
$164 nightly
The price is $183 total per night from Jan 28 to Jan 29
$183 total
Jan 28 - Jan 29
Total with taxes and fees
Book a stay at this golf hotel in Medford. Enjoy free breakfast, free parking, and a 24-hour fitness center. Our guests praise the breakfast and the pool in ...
9.6/10 Exceptional! (1,009 reviews)
Property was clean Staff very friendly and helpful. Only draw back was the water pressure in the shower. So bad!

Reviewed on Jan 26, 2026

Compass by Margaritaville in Medford
Motel 6 Medford, OR - North

Motel 6 Medford, OR - North

2 out of 5
2400 Biddle Rd Medford OR
$41 nightly
The price is $46 total per night from Feb 11 to Feb 12
$46 total
Feb 11 - Feb 12
Total with taxes and fees
Stay at this motel in Medford. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,089 reviews)
Clean room! Big bathroom Needs more pillows though..room only had two

Reviewed on Jan 18, 2026

Motel 6 Medford, OR - North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Medford Hotels With Airport Transportation

Inn at the Commons

Inn at the Commons

4 out of 5
200 N Riverside Ave Medford OR
Stay at this inn in Medford. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Children's Museum and Rogue Valley Growers and Crafters Market ...
Needs upkeeping and non-smoking rooms/area.
Our non-smoking room was in need of repair with peeling paints/molded bathroom. Both queen beds had strong smoking odor. 3 out of 4 times that we came out of the room, we ran into smokers congregating in the parking lot a few feet from our door.

Reviewed on Feb 9, 2021

Get rates
Inn at the Commons
Quality Inn & Suites Medford Airport

Quality Inn & Suites Medford Airport

2.5 out of 5
1950 Biddle Rd Medford OR
$70 nightly
The price is $79 total per night from Feb 25 to Feb 26
$79 total
Feb 25 - Feb 26
Total with taxes and fees
Book a stay at this spa hotel in Medford. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. ...
8.4/10 Very Good! (1,002 reviews)
Great stay! Clean room with updating flooring and tv. Bed was very comfy. Lots of parking right in front of our room.

Reviewed on Jan 25, 2026

Quality Inn & Suites Medford Airport
Rogue Regency Inn and Suites

Rogue Regency Inn and Suites

3 out of 5
2300 Biddle Rd Medford OR
$85 nightly
The price is $95 total per night from Jan 28 to Jan 29
$95 total
Jan 28 - Jan 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Medford. Enjoy free breakfast, free WiFi, and a free airport shuttle. Our guests praise the breakfast and the ...
8.8/10 Excellent! (2,793 reviews)
staff good. room good but old. no complaints and would stay again.

Reviewed on Jan 22, 2026

Rogue Regency Inn and Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Medford Hotels

Cedarwood Inn of Ashland

Cedarwood Inn of Ashland

2 out of 5
Siskiyou Blvd, 1801 Ashland OR
$75 nightly
The price is $84 total per night from Feb 19 to Feb 20
$84 total
Feb 19 - Feb 20
Total with taxes and fees
Book a stay at this business-friendly hotel in Ashland. Enjoy free WiFi, free parking, and a sauna. Our guests praise the helpful staff in our reviews. Popular ...
7.2/10 Good! (997 reviews)
We’ve stayed here twice. Nice place for reasonable price.

Reviewed on Nov 18, 2025

Cedarwood Inn of Ashland
Motel 6 Medford, OR - North

Motel 6 Medford, OR - North

2 out of 5
2400 Biddle Rd Medford OR
$41 nightly
The price is $46 total per night from Feb 11 to Feb 12
$46 total
Feb 11 - Feb 12
Total with taxes and fees
Stay at this motel in Medford. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
7.2/10 Good! (1,089 reviews)
Clean room! Big bathroom Needs more pillows though..room only had two

Reviewed on Jan 18, 2026

Motel 6 Medford, OR - North
Pine Tree Inn

Pine Tree Inn

2 out of 5
509 North Riverside Avenue Medford OR
$64 nightly
The price is $73 total per night from Jan 28 to Jan 29
$73 total
Jan 28 - Jan 29
Total with taxes and fees
Book a stay at this business-friendly motel in Medford. Enjoy free WiFi, free parking, and room service. Our guests praise the helpful staff in our reviews. ...
7.4/10 Good! (615 reviews)
Wasn’t bad at all

Reviewed on Nov 3, 2025

Pine Tree Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Medford

Ashland Hills Hotel & Suites

Ashland Hills Hotel & Suites

3 out of 5
2525 Ashland St Ashland OR
$106 nightly
The price is $118 total per night from Jan 28 to Jan 29
$118 total
Jan 28 - Jan 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Ashland. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the breakfast and the helpful ...
8.8/10 Excellent! (1,481 reviews)
Great location for highway travellers! Only 1 minute off the route. I didnt stay long, but it was a great spot to rest after driving for 14 hours. It felt retro and modern at the same time. Interesting vibe. It was quiet and clean.

Reviewed on Jan 24, 2026

Ashland Hills Hotel & Suites
Inn at the Commons

Inn at the Commons

4 out of 5
200 N Riverside Ave Medford OR
Stay at this inn in Medford. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Children's Museum and Rogue Valley Growers and Crafters Market ...
Needs upkeeping and non-smoking rooms/area.
Our non-smoking room was in need of repair with peeling paints/molded bathroom. Both queen beds had strong smoking odor. 3 out of 4 times that we came out of the room, we ran into smokers congregating in the parking lot a few feet from our door.

Reviewed on Feb 9, 2021

Get rates
Inn at the Commons
Plaza Inn & Suites at Ashland Creek

Plaza Inn & Suites at Ashland Creek

3 out of 5
98 Central Ave Ashland OR
$119 nightly
The price is $133 total per night from Jan 28 to Jan 29
$133 total
Jan 28 - Jan 29
Total with taxes and fees
Book a stay at this business-friendly hotel in Ashland. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.6/10 Excellent! (1,013 reviews)
Clean room, Quiet, Pet friendly

Reviewed on Jan 25, 2026

Plaza Inn & Suites at Ashland Creek
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

DSM to MFR Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

Are there non-stop flights from Des Moines Intl. Airport to Rogue Valley Intl. Airport (MFR)?
As you can't fly direct from DSM to Rogue Valley Intl. Airport (MFR) at the moment, a flight with just one stopover is your best option. United Airlines, American Airlines and Delta Air Lines are all reputable airlines that service this route.
What is the shortest flight from DSM to MFR?
The fastest you can fly from Des Moines Intl. Airport (DSM) to MFR is 5 hours and 23 minutes. Pack a few things in your carry-on to keep you amused, like that new best-seller or some Sudoku puzzles.
How many hours flight from Des Moines Intl. Airport to Rogue Valley Intl. Airport (MFR)?
It usually takes about 5 hours and 38 minutes to jet from DSM to MFR. Get through the flight by watching movies and listening to podcasts. Alternatively, use the time to catch up on some sleep.
What airlines have the most flights from Des Moines Intl. Airport to MFR?
For now, there are no airlines that operate direct flights from DSM to Medford Airport. Don't panic though! There are lots of single or multi-stop options available.

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.