$101 Cheap flight deals from Des Moines (DSM) to San Ysidro (SAN)
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This Weekend's Flight Deals from Des Moines to San Ysidro
This weekend's flight prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
Airfares from $101 One Way, $228 Round Trip from Des Moines to San Ysidro
Prices starting at $228 for return flights and $101 for one-way flights to San Ysidro were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.
San Ysidro economy flight packages
The Beau Downtown San Diego Gaslamp Quar
Apr 23 - Apr 27
Des Moines (DSM) to San Diego (SAN)
San Diego (SAN) to Des Moines (DSM)
Reviewed on Aug 28, 2025
The Sofia Hotel
Apr 23 - Apr 27
Des Moines (DSM) to San Diego (SAN)
San Diego (SAN) to Des Moines (DSM)
Reviewed on Jan 5, 2026
Margaritaville Hotel San Diego Gaslamp Quarter
Apr 23 - Apr 27
Des Moines (DSM) to San Diego (SAN)
San Diego (SAN) to Des Moines (DSM)
Reviewed on Oct 3, 2025
San Ysidro first class flight packages
Fairmont Grand Del Mar
May 6 - May 10
Des Moines (DSM) to San Diego (SAN)
Reviewed on Sep 26, 2024
Shore House at The Del, LXR Hotels & Resorts
May 6 - May 10
Des Moines (DSM) to San Diego (SAN)
Reviewed on Jul 22, 2024
More About Flying To San Ysidro from Des Moines
Route Information for Flights from Des Moines to San Ysidro
Origin Airport IATA Code | DSM |
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Destination Airport IATA Code | SAN |
Distance | |
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Des Moines to San Ysidro
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Cruising for a bargain deal
Regardless of your destination, we always provide you fantastic bargains for your trip, and that includes on hotels and even cruises. We offer budget air fares on flights from Des Moines to San Ysidro so you can reach your destination with more money in your pocket to spend.
Cheap Des Moines to San Ysidro flights that lead to rewards
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Quality combinations
If you require budget Des Moines to San Ysidro flights and a bargain hotel to go with it, Orbitz will wow you with the great combinations we can offer. The quality is always high and always a superb value.
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Flights from Des Moines
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Des Moines Airports
Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.
Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.
Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.