Cheap flights from SAF to DSM (Santa Fe Municipal to Des Moines Intl.)

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Cheap Flights from SAF to DSM starting at $246 One Way, Round Trip

Prices starting at for return flights and $246 for one-way flights to Des Moines Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply.

Hotel Ideas near Des Moines Intl.

Airport Hotels near Des Moines Intl.

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$66 nightly
The price is $74 total per night from Feb 1 to Feb 2
$74 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,727 reviews)
The room was clean and the receptionist was very friendly.

Reviewed on Jan 18, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$109 nightly
The price is $122 total per night from Jan 24 to Jan 25
$122 total
Jan 24 - Jan 25
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,000 reviews)
The entryway area was extremely clean when we arrived. The lady at the desk was courteous and knowledgeable. The breakfast was the standard motel breakfast. The desk help was mopping and vacuuming the entry way in the morning. Very nice.

Reviewed on Jan 19, 2026

Hampton Inn Des Moines-Airport
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr Des Moines IA
$61 nightly
The price is $69 total per night from Feb 1 to Feb 2
$69 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,003 reviews)
Clean room, smell clean when you walk in , staff very polite. Clean rooms, housekeepers daily.

Reviewed on Jan 19, 2026

Quality Inn & Suites Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Hotels In Des Moines

Hotel Fort Des Moines, Curio Collection by Hilton

Hotel Fort Des Moines, Curio Collection by Hilton

4.5 out of 5
1000 Walnut St Des Moines IA
$144 nightly
The price is $161 total per night from Feb 15 to Feb 16
$161 total
Feb 15 - Feb 16
Total with taxes and fees
Book a stay at this luxury hotel in Des Moines. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the clean rooms ...
9.4/10 Exceptional! (1,071 reviews)
Very nice hotel.

Reviewed on Jan 12, 2026

Hotel Fort Des Moines, Curio Collection by Hilton
Stoney Creek Hotel Des Moines - Johnston

Stoney Creek Hotel Des Moines - Johnston

2.5 out of 5
5291 Stoney Creek Court Johnston IA
$83 nightly
The price is $93 total per night from Jan 29 to Jan 30
$93 total
Jan 29 - Jan 30
Total with taxes and fees
Book a stay at this business-friendly hotel in Johnston. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
8.8/10 Excellent! (1,815 reviews)
Great Staff

Reviewed on Jan 20, 2026

Stoney Creek Hotel Des Moines - Johnston
Home2 Suites by Hilton Des Moines at Drake University

Home2 Suites by Hilton Des Moines at Drake University

3 out of 5
2650 University Ave. Des Moines IA
$89 nightly
The price is $100 total per night from Jan 27 to Jan 28
$100 total
Jan 27 - Jan 28
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
9.2/10 Wonderful! (1,004 reviews)
Clean modern rooms, hallways, and lobby. Loved not having an alarm clock in the room as many times they are pre set for the alarm from the last visitor. I loved how the hallway door had a barrier all the way down to the floor so you could not see the hallway light underneath it.

Reviewed on Jan 18, 2026

Home2 Suites by Hilton Des Moines at Drake University
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Des Moines Hotels With Airport Transportation

Days Inn & Suites by Wyndham Des Moines Airport

Days Inn & Suites by Wyndham Des Moines Airport

2 out of 5
1901 Hackley Ave Des Moines IA
$66 nightly
The price is $74 total per night from Feb 1 to Feb 2
$74 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
8.4/10 Very Good! (1,727 reviews)
The room was clean and the receptionist was very friendly.

Reviewed on Jan 18, 2026

Days Inn & Suites by Wyndham Des Moines Airport
Quality Inn & Suites Des Moines Airport

Quality Inn & Suites Des Moines Airport

2.5 out of 5
5231 Fleur Dr Des Moines IA
$61 nightly
The price is $69 total per night from Feb 1 to Feb 2
$69 total
Feb 1 - Feb 2
Total with taxes and fees
Book a stay at this business-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
7.2/10 Good! (1,003 reviews)
Clean room, smell clean when you walk in , staff very polite. Clean rooms, housekeepers daily.

Reviewed on Jan 19, 2026

Quality Inn & Suites Des Moines Airport
Hampton Inn Des Moines-Airport

Hampton Inn Des Moines-Airport

2.5 out of 5
5001 Fleur Dr Des Moines IA
$109 nightly
The price is $122 total per night from Jan 24 to Jan 25
$122 total
Jan 24 - Jan 25
Total with taxes and fees
Stay at this hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8.8/10 Excellent! (1,000 reviews)
The entryway area was extremely clean when we arrived. The lady at the desk was courteous and knowledgeable. The breakfast was the standard motel breakfast. The desk help was mopping and vacuuming the entry way in the morning. Very nice.

Reviewed on Jan 19, 2026

Hampton Inn Des Moines-Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Low Priced Des Moines Hotels

Motel 6 West Des Moines, IA

Motel 6 West Des Moines, IA

2 out of 5
7655 Office Plaza Dr N West Des Moines IA
$46 nightly
The price is $51 total per night from Feb 5 to Feb 6
$51 total
Feb 5 - Feb 6
Total with taxes and fees
Stay at this motel in West Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our ...
7.8/10 Good! (736 reviews)
Yes

Reviewed on Jan 11, 2026

Motel 6 West Des Moines, IA
Cozy Rest Motel

Cozy Rest Motel

2 out of 5
2316 Southeast 14th Street Des Moines IA
$71 nightly
The price is $80 total per night from Jan 25 to Jan 26
$80 total
Jan 25 - Jan 26
Total with taxes and fees
Stay at this motel in Des Moines. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews. Popular attractions ...
7.6/10 Good! (651 reviews)
This was a no frills place to stay but the room was nice and the front desk guy was friendly. If you are looking for a cheap but nice place to stay, check them out.

Reviewed on Sep 25, 2025

Cozy Rest Motel
Quality Inn

Quality Inn

2 out of 5
1258 8th St West Des Moines IA
$51 nightly
The price is $57 total per night from Feb 22 to Feb 23
$57 total
Feb 22 - Feb 23
Total with taxes and fees
Book a stay at this business-friendly hotel in West Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the clean rooms in our reviews. ...
6.8/10 (20 reviews)
Room was clean. Nice safe location The front desk person was friendly. Great budget hotel if you’re going to a concert at the Val air ballroom it’s walking distance. across the street You have gas station and a couple fast food options,. This will be my regular hotel for when I go see concerts at ...

Reviewed on Nov 19, 2025

Quality Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Family Friendly Hotels in Des Moines

Wildwood Lodge

Wildwood Lodge

3 out of 5
11431 Forest Ave Clive IA
$95 nightly
The price is $107 total per night from Jan 25 to Jan 26
$107 total
Jan 25 - Jan 26
Total with taxes and fees
Stay at this hotel in Clive. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.4/10 Exceptional! (1,216 reviews)
Great stay with our kids!

Reviewed on Jan 18, 2026

Wildwood Lodge
Ramada Tropics Resort & Conf Center by Wyndham Des Moines

Ramada Tropics Resort & Conf Center by Wyndham Des Moines

3 out of 5
5000 Merle Hay Rd Urbandale IA
$70 nightly
The price is $78 total per night from Jan 25 to Jan 26
$78 total
Jan 25 - Jan 26
Total with taxes and fees
Book a stay at this family-friendly hotel in Urbandale. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...
5.6/10 (689 reviews)

Families like: Kids pool, waterpark, game room, cribs

Travelers say...
Amenities

Reviewed on Jan 12, 2026

Ramada Tropics Resort & Conf Center by Wyndham Des Moines
Baymont by Wyndham Des Moines Airport

Baymont by Wyndham Des Moines Airport

2.5 out of 5
6221 Willow Creek Ave Des Moines IA
$89 nightly
The price is $100 total per night from Jan 24 to Jan 25
$100 total
Jan 24 - Jan 25
Total with taxes and fees
Book a stay at this family-friendly hotel in Des Moines. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the pool in our ...
9.2/10 Wonderful! (1,172 reviews)

Families like: Game room, cribs, rollaway beds, games and toys

Travelers say...
Very nice, comfortable accommodations. Would definitely stay again.

Reviewed on Jan 18, 2026

Baymont by Wyndham Des Moines Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

SAF to DSM Route Info

Origin Airport
Destination Airport
Number Of Airlines Serving
Distance
Shortest Flight Departure Time
Shortest Flight Departure Date

Frequently asked questions

What is the shortest flight from SAF to Des Moines Intl. Airport?
Jetting from Santa Fe Regional Airport to DSM will take a minimum of 3 hours and 50 minutes. Enjoy a wine and read a few magazines — this is the perfect opportunity to kick back and unwind.
How many hours flight from Santa Fe Municipal Airport (SAF) to Des Moines Intl. Airport (DSM)?
On average, flying from Santa Fe Municipal Airport (SAF) to DSM takes 4 hours and 1 minute. If you'd like to be as comfy as possible, think about upgrading your seat using air miles or cash.
What airlines have the most flights from Santa Fe Municipal Airport (SAF) to Des Moines Intl. Airport?
At the moment, you won't find any direct flights between Santa Fe and Des Moines. However, you will find flights with one or more stops. There's always a silver lining — use the break to stretch your legs or go in search of a nice meal!

Map To Nearby Hotels

Fare, taxes & fees: Fares include all taxes and fees, except baggage fees. Rates shown reflect fares found by other Orbitz users over the past 7 days. Due to rapidly changing airline prices & seat availability, these fares may no longer be available.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a $30 service fee charged by Orbitz. Additional airline charges may apply.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Lower fares may be available. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.